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Protein Ontology report - cGMP-specific 3',5'-cyclic phosphodiesterase
PR:000012477 - http://purl.obolibrary.org/obo/PR_000012477
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000012477   
  PRO namecGMP-specific 3',5'-cyclic phosphodiesterase 
  Synonyms
PRO-Short-label: EXACT:PDE5A
Gene-based: RELATED:PDE5
Other: EXACT:CGB-PDE | cGMP-binding cGMP-specific phosphodiesterase
  Definition"A GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase that is a translation product of the human PDE5A gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000050164 GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1304
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012477

cGMP-specific 3',5'-cyclic phosphodiesterase

PDE5A


"A GAF-containing cyclic nucleotide-dependent 3',5'-cyclic phosphodiesterase that is a translation product of the human PDE5A gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O54735

cGMP-specific 3',5'-cyclic phosphodiesterase (rat)

rPDE5A


"A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:O54735-1

cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 (rat)

rPDE5A/iso:PDE5A2


"A cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:O54735-2

cGMP-specific 3',5'-cyclic phosphodiesterase isoform rPDE5A1 (rat)

rPDE5A/iso:rPDE5A1


"A cGMP-specific 3',5'-cyclic phosphodiesterase (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O54735-2." [PRO:DNx, UniProtKB:O54735]


organism-gene



PR:O76074

cGMP-specific 3',5'-cyclic phosphodiesterase (human)

hPDE5A


"A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of human." [PRO:DNx, UniProtKB:O76074]


organism-sequence



PR:O76074-1

cGMP-specific 3',5'-cyclic phosphodiesterase isoform hPDE5A1 (human)

hPDE5A/iso:hPDE5A1


"A cGMP-specific 3',5'-cyclic phosphodiesterase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76074-1." [PRO:DNx, UniProtKB:O76074]


organism-sequence



PR:O76074-2

cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 (human)

hPDE5A/iso:PDE5A2


"A cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000045614

cGMP-specific 3',5'-cyclic phosphodiesterase phosphorylated 1 (human)

hPDE5A/Phos:1


"A cGMP-specific 3',5'-cyclic phosphodiesterase (human) that has been phosphorylated on the residue at the position equivalent to Ser-102 of the amino acid sequence represented by UniProtKB:O76074-1. Example: UniProtKB:O76074-1, Ser-102, MOD:00046." [iPTMnet:O76074, PMID:16690614]


organism-modification



PR:000084927

cGMP-specific 3',5'-cyclic phosphodiesterase methylated 1 (human)

hPDE5A/Me:1


"A cGMP-specific 3',5'-cyclic phosphodiesterase (human) that has been methylated on the residue at the position equivalent to Cys-689 of the amino acid sequence represented by UniProtKB:O76074-1. Example: UniProtKB:O76074-1, Cys-689, MOD:00660." [IEDB_epitope:1017961, PRO:DNx]


organism-gene



PR:Q28156

cGMP-specific 3',5'-cyclic phosphodiesterase (cow)

cow-PDE5A


"A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of cow." [OMA:Q28156, PRO:DNx]


organism-gene



PR:Q8CG03

cGMP-specific 3',5'-cyclic phosphodiesterase (mouse)

mPDE5A


"A cGMP-specific 3',5'-cyclic phosphodiesterase that is encoded in the genome of mouse." [OMA:Q8CG03, PRO:DNx]


sequence



PR:000038430

cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2

PDE5A/iso:PDE5A2


"A cGMP-specific 3',5'-cyclic phosphodiesterase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O76074-2 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:O54735-1

cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 (rat)

rPDE5A/iso:PDE5A2


"A cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:O76074-2

cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 (human)

hPDE5A/iso:PDE5A2


"A cGMP-specific 3',5'-cyclic phosphodiesterase isoform PDE5A2 that is encoded in the genome of human." [PRO:DNx]