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Protein Ontology report - 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1
PR:000012578 - http://purl.obolibrary.org/obo/PR_000012578
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000012578   
  PRO name6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 
  Synonyms
PRO-Short-label: EXACT:PFKFB1
Gene-based: RELATED:F6PK | PFRX
Other: EXACT:6PF-2-K/Fru-2,6-P2ase 1 | 6PF-2-K/Fru-2,6-P2ase liver isozyme | PFK/FBPase 1
  Definition"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase that is a translation product of the human PFKFB1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000029977 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence1                                                  Organism-Sequence 6                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000012578

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1

PFKFB1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase that is a translation product of the human PFKFB1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P07953

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (rat)

rPFKFB1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 that is encoded in the genome of rat." [OMA:P07953, PRO:DNx]


organism-sequence



PR:P07953-1

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 (rat)

rPFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P07953-2

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform r2 (rat)

rPFKFB1/iso:r2


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07953-2." [PRO:DNx, UniProtKB:P07953]


organism-gene



PR:P16118

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (human)

hPFKFB1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P16118-1

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 (human)

hPFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P16118-2

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform h2 (human)

hPFKFB1/iso:h2


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16118-2." [PRO:DNx, UniProtKB:P16118]


organism-modification



PR:000042034

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed form (human)

hPFKFB1/InitMet-


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (human) that has had the initiator methionine removed. Example: UniProtKB:P16118-1, 2-471." [PRO:DAN]


Yes
organism-modification



PR:000026776

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed phosphorylated 1 (human)

hPFKFB1/InitMet-/Phos:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed phosphorylated 1 in human. Example: UniProtKB:P16118-1, 2-471, Ser-33, MOD:00046." [PRO:DAN, Reactome:R-HSA-163749]


Yes
organism-gene



PR:P70266

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (mouse)

mPFKFB1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 that is encoded in the genome of mouse." [OMA:P70266, PRO:DNx]


organism-sequence



PR:P70266-1

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 (mouse)

mPFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P70266-2

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform m2 (mouse)

mPFKFB1/iso:m2


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70266-2." [PRO:DNx, UniProtKB:P70266]


sequence



PR:000038947

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1

PFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P16118-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P07953-1

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 (rat)

rPFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:P16118-1

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 (human)

hPFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P70266-1

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 (mouse)

mPFKFB1/iso:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000026774

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed phosphorylated form

PFKFB1/InitMet-/PhosRes+


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 that has had the initiator methionine removed and that includes at least one phosphorylated residue." [PRO:DAN]


modification



PR:000026775

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed phosphorylated 1

PFKFB1/InitMet-/Phos:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Ser-33 of the amino acid sequence represented by UniProtKB:P16118-1. Example: UniProtKB:P16118-1, 2-471, Ser-33, MOD:00046." [PRO:DAN]


organism-modification



PR:000026776

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed phosphorylated 1 (human)

hPFKFB1/InitMet-/Phos:1


"A 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1, initiator methionine removed phosphorylated 1 in human. Example: UniProtKB:P16118-1, 2-471, Ser-33, MOD:00046." [PRO:DAN, Reactome:R-HSA-163749]


Yes
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PFKFB1 forms found in complexes   

PFKFB1 Component
Complexes
PR:000026776 hPFKFB1/InitMet-/Phos:1 PR:000026777 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase complex, phosphorylated form (human)
PR:000042034 hPFKFB1/InitMet- PR:000026767 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase complex (human)