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Protein Ontology report - DNA polymerase beta
PR:000012962 - http://purl.obolibrary.org/obo/PR_000012962
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000012962   
  PRO nameDNA polymerase beta 
  Synonyms
PRO-Short-label: EXACT:POLB
Other: EXACT:5'-deoxyribose-phosphate lyase | 5'-dRP lyase | AP lyase
  Definition"A protein that is a translation product of the human POLB gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 1                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000012962 DNA polymerase beta
POLB

organism-gene


PR:P06746 DNA polymerase beta (human)
hPOLB

organism-sequence


PR:P06746-1 DNA polymerase beta isoform 1 (human)
hPOLB/iso:1

organism-modification


PR:000028604 DNA polymerase beta acetylated 1 (human)
hPOLB/Ac:1
Yes
organism-modification


PR:000045373 DNA polymerase beta unacetylated 1 (human)
hPOLB/UnAc:1
Yes
organism-modification


PR:000048840 DNA polymerase beta, initiator methionine removed ubiquitinated form (human)
hPOLB/InitMet-/UbiqLys+

organism-gene


PR:P06766 DNA polymerase beta (rat)
rPOLB

organism-gene


PR:Q6DRD3 DNA polymerase beta (zebrafish)
z-POLB

organism-gene


PR:Q8K409 DNA polymerase beta (mouse)
mPOLB

organism-gene


PR:Q9FNY4 DNA polymerase lambda (Arabidopsis thaliana)
At-POLB

sequence


PR:000028601 DNA polymerase beta isoform 1
POLB/iso:1

organism-sequence


PR:P06746-1 DNA polymerase beta isoform 1 (human)
hPOLB/iso:1

modification


PR:000028603 DNA polymerase beta acetylated 1
POLB/Ac:1

organism-modification


PR:000028604 DNA polymerase beta acetylated 1 (human)
hPOLB/Ac:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000028604 hPOLB/Ac:1
UniProtKB:P06746, Lys-72, MOD:00064		 enablesdecreased GO:0016829 lyase activity relative to PR:000045373 DNA polymerase beta unmodified form (human) PMID:12453427
PR:000045373 hPOLB/UnAc:1
UniProtKB:P06746, Lys-72, PR:000026291		 acts_upstream_of_or_withinGO:0006284 base-excision repair PMID:12453427
enablesGO:0016829 lyase activity PMID:12453427