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Protein Ontology report - prostaglandin G/H synthase 2
PR:000013428 - http://purl.obolibrary.org/obo/PR_000013428
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000013428   
  PRO nameprostaglandin G/H synthase 2 
  Synonyms
PRO-Short-label: EXACT:PTGS2
Gene-based: RELATED:COX2 | Pghs-b | Tis10
Other: EXACT:COX-2 | cyclooxygenase-2 | glucocorticoid-regulated inflammatory cyclooxygenase | gripghs | macrophage activation-associated marker protein P71/73 | PES-2 | PGH synthase 2 | PGHS-2 | PHS II | prostaglandin H2 synthase 2 | prostaglandin-endoperoxide synthase 2 | TIS10 protein
  Definition"A protein that is a translation product of the human PTGS2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 6                                        
         Sequence1                                                  Organism-Sequence 3                                        
         Modification1                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:1376
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000013428

prostaglandin G/H synthase 2

PTGS2


"A protein that is a translation product of the human PTGS2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O62698

prostaglandin G/H synthase 2 (cow)

cow-PTGS2


"A prostaglandin G/H synthase 2 that is encoded in the genome of cow." [OMA:O62698, PRO:DNx]


organism-gene



PR:P27607

prostaglandin G/H synthase 2 (chicken)

chick-PTGS2


"A prostaglandin G/H synthase 2 that is encoded in the genome of chicken." [OMA:P27607, PRO:DNx]


organism-gene



PR:P35354

prostaglandin G/H synthase 2 (human)

hPTGS2


"A prostaglandin G/H synthase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P35354]


organism-sequence



PR:P35354-1

prostaglandin G/H synthase 2 isoform 1 (human)

hPTGS2/iso:1


"A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000048946

prostaglandin G/H synthase 2, signal peptide removed form (human)

hPTGS2/SigPep-


"A prostaglandin G/H synthase 2 (human) that has had the signal peptide removed. UniProtKB:P35354, 18-604." [PRO:DNx, Reactome:R-HSA-61605]


organism-modification



PR:000061609

prostaglandin G/H synthase 2, signal peptide removed acetylated 1 (human)

hPTGS2/SigPep-/Ac:1


"A prostaglandin G/H synthase 2 (human) that has had the signal peptide removed and that has been acetylated on the residue at the position equivalent to Ser-516 of the amino acid sequence represented by UniProtKB:P35354. UniProtKB:P35354, 18-604, Ser-516, MOD:00369." [PRO:DNx, Reactome:R-HSA-2161824]


organism-modification



PR:000056384

prostaglandin G/H synthase 2 N-glycosylated 1 (human)

hPTGS2/NGlyco:1


"A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-130 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P35354-1, Asn-130, MOD:00160~GNO:G25079LO." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000056385

prostaglandin G/H synthase 2 N-glycosylated 2 (human)

hPTGS2/NGlyco:2


"A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-130 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G46503DX. Example: UniProtKB:P35354-1, Asn-130, MOD:00160~GNO:G46503DX." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000056386

prostaglandin G/H synthase 2 N-glycosylated 3 (human)

hPTGS2/NGlyco:3


"A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-53 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G01650EU. Example: UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G01650EU." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000056387

prostaglandin G/H synthase 2 N-glycosylated 4 (human)

hPTGS2/NGlyco:4


"A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-53 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G25079LO. Example: UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G25079LO." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000056388

prostaglandin G/H synthase 2 N-glycosylated 5 (human)

hPTGS2/NGlyco:5


"A prostaglandin G/H synthase 2 (human) that has been N-glycosylated at the residue equivalent to Asn-53 of the amino acid sequence represented by UniProtKB:P35354-1, in which the glycan composition is represented by GlyTouCan:G46503DX. Example: UniProtKB:P35354-1, Asn-53, MOD:00160~GNO:G46503DX." [GlyGen:P35354-1, PMID:29741879, PRO:DNx]


organism-modification



PR:000067737

prostaglandin G/H synthase 2 deaminated 1 (human)

hPTGS2/Deam:1


"A prostaglandin G/H synthase 2 (human) that has been deaminated on the residue at the position equivalent to Asn-396 of the amino acid sequence represented by UniProtKB:P35354. UniProtKB:P35354, Asn-396, MOD:00684." [IEDB_epitope:1978385, PRO:DNx]


organism-gene



PR:P35355

prostaglandin G/H synthase 2 (rat)

rPTGS2


"A prostaglandin G/H synthase 2 that is encoded in the genome of rat." [OMA:P35355, PRO:DNx]


organism-sequence



PR:P35355-1

prostaglandin G/H synthase 2 isoform 1 (rat)

rPTGS2/iso:1


"A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:P79208

prostaglandin G/H synthase 2 (sheep)

sheep-PTGS2


"A prostaglandin G/H synthase 2 that is encoded in the genome of sheep." [OMA:P79208, PRO:DNx]


organism-gene



PR:Q05769

prostaglandin G/H synthase 2 (mouse)

mPTGS2


"A prostaglandin G/H synthase 2 that is encoded in the genome of mouse." [OMA:Q05769, PRO:DNx]


organism-sequence



PR:Q05769-1

prostaglandin G/H synthase 2 isoform 1 (mouse)

mPTGS2/iso:1


"A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000058516

prostaglandin G/H synthase 2 N-glycosylated 1 (mouse)

mPTGS2/NGlyco:1


"A prostaglandin G/H synthase 2 (mouse) that has been N-glycosylated at the residue equivalent to Asn-130 of the amino acid sequence represented by UniProtKB:Q05769-1, in which the glycan structure is represented by GlyTouCan:G62768NK. Example: UniProtKB:Q05769-1, Asn-130, MOD:00160~GNO:G62768NK." [GlyGen:Q05769-1, PMID:11258925, PRO:DNx]


sequence



PR:000039332

prostaglandin G/H synthase 2 isoform 1

PTGS2/iso:1


"A prostaglandin G/H synthase 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35354-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P35354-1

prostaglandin G/H synthase 2 isoform 1 (human)

hPTGS2/iso:1


"A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P35355-1

prostaglandin G/H synthase 2 isoform 1 (rat)

rPTGS2/iso:1


"A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q05769-1

prostaglandin G/H synthase 2 isoform 1 (mouse)

mPTGS2/iso:1


"A prostaglandin G/H synthase 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000021167

prostaglandin G/H synthase 2, signal peptide removed form

PTGS2/SigPep-


"A prostaglandin G/H synthase 2 that has had the signal peptide removed." [PRO:DNx]


organism-modification



PR:000048946

prostaglandin G/H synthase 2, signal peptide removed form (human)

hPTGS2/SigPep-


"A prostaglandin G/H synthase 2 (human) that has had the signal peptide removed. UniProtKB:P35354, 18-604." [PRO:DNx, Reactome:R-HSA-61605]


organism-modification



PR:000061609

prostaglandin G/H synthase 2, signal peptide removed acetylated 1 (human)

hPTGS2/SigPep-/Ac:1


"A prostaglandin G/H synthase 2 (human) that has had the signal peptide removed and that has been acetylated on the residue at the position equivalent to Ser-516 of the amino acid sequence represented by UniProtKB:P35354. UniProtKB:P35354, 18-604, Ser-516, MOD:00369." [PRO:DNx, Reactome:R-HSA-2161824]