back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - receptor-interacting serine/threonine-protein kinase 3
PR:000014024 - http://purl.obolibrary.org/obo/PR_000014024
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000014024   
  PRO namereceptor-interacting serine/threonine-protein kinase 3 
  Synonyms
PRO-Short-label: EXACT:RIPK3
Gene-based: RELATED:RIP3
Other: EXACT:receptor-interacting protein 3 | RIP-3 | RIP-like protein kinase 3
  Definition"A protein that is a translation product of the human RIPK3 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Related Cross References

  Db identifiers
IUPHARobj:2191
Back to top
Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000014024

receptor-interacting serine/threonine-protein kinase 3

RIPK3


"A protein that is a translation product of the human RIPK3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q1PDW3

receptor-like kinase LIP1 (Arabidopsis thaliana)

At-RIPK3


"A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q1PDW3, PRO:DNx]


organism-gene



PR:Q9QZL0

receptor-interacting serine/threonine-protein kinase 3 (mouse)

mRIPK3


"A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of mouse." [OMA:Q9QZL0, PRO:DNx]


organism-gene



PR:Q9Y572

receptor-interacting serine/threonine-protein kinase 3 (human)

hRIPK3


"A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of human." [PRO:CNA, Reactome:R-HSA-450328]

Yes

Yes
organism-sequence



PR:Q9Y572-1

receptor-interacting serine/threonine-protein kinase 3 isoform h1 (human)

hRIPK3/iso:h1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y572-1." [PRO:DNx, UniProtKB:Q9Y572]


organism-sequence



PR:Q9Y572-2

receptor-interacting serine/threonine-protein kinase 3 isoform h2 (human)

hRIPK3/iso:h2


"A receptor-interacting serine/threonine-protein kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y572-2." [PRO:DNx, UniProtKB:Q9Y572]


organism-sequence



PR:Q9Y572-3

receptor-interacting serine/threonine-protein kinase 3 isoform h3 (human)

hRIPK3/iso:h3


"A receptor-interacting serine/threonine-protein kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y572-3." [PRO:DNx, UniProtKB:Q9Y572]


organism-modification



PR:000049047

receptor-interacting serine/threonine-protein kinase 3 phosphorylated 1 (human)

hRIPK3/Phos:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been post-translationally modified to include phosphoserine at positions 199 and 227 of the amino acid sequence represented by UniProtKB:Q9Y572. UniProtKB:Q9Y572, Ser-199/Ser-227, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218873]


organism-modification



PR:000064444

receptor-interacting serine/threonine-protein kinase 3 ubiquitinated 1 (human)

hRIPK3/Ubiq:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been ubiquitinated on the residues at the positions equivalent to Lys-55 and Lys-363 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Lys-55/Lys-363, MOD:01148." [PRO:DNx, Reactome:R-HSA-9688825]


organism-modification



PR:000064690

receptor-interacting serine/threonine-protein kinase 3 phosphorylated and ubiquitinated 1 (human)

hRIPK3/PhosUbiq:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been phosphorylated on the residues at the positions equivalent to Ser-199 and Ser-227 and ubiquitinated on the residue at the position equivalent to Lys-363 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Ser-199/Ser-227, MOD:00046|Lys-363, MOD:01148." [PRO:DNx, Reactome:R-HSA-9686933]


organism-modification



PR:000064837

receptor-interacting serine/threonine-protein kinase 3 ubiquitinated 2 (human)

hRIPK3/Ubiq:2


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been ubiquitinated on the residues at the positions equivalent to Lys-197, Lys-302, and Lys-364 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Lys-197/Lys-302/Lys-364, MOD:01148." [PRO:DNx, Reactome:R-HSA-9794180]


organism-modification



PR:000064845

receptor-interacting serine/threonine-protein kinase 3 O-glycosylated 1 (human)

hRIPK3/OGlyco:1


"A receptor-interacting serine/threonine-protein kinase 3 (human) that has been O-glycosylated on the residue at the position equivalent to Thr-467 of the amino acid sequence represented by UniProtKB:Q9Y572-1. Example: UniProtKB:Q9Y572-1, Thr-467, MOD:00005." [PRO:DNx, Reactome:R-HSA-9687819]


organism-gene



PR:Q9Z2P5

receptor-interacting serine/threonine-protein kinase 3 (rat)

rRIPK3


"A receptor-interacting serine/threonine-protein kinase 3 that is encoded in the genome of rat." [OMA:Q9Z2P5, PRO:DNx]


Back to top
RIPK3 forms found in complexes   

RIPK3 Component
Complexes
PR:Q9Y572 hRIPK3 PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
PR:000037332 rip3:ticam1:activated TLR3 complex (human)
PR:000037336 rip1:rip3:ticam1:activated TLR3 complex (human)
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q9Y572 hRIPK3 located_inGO:0005737 cytoplasm Reactome:REACT_22021