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Protein Ontology report - retinoic acid receptor RXR-alpha
PR:000014372 - http://purl.obolibrary.org/obo/PR_000014372
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000014372   
  PRO nameretinoic acid receptor RXR-alpha 
  Synonyms
PRO-Short-label: EXACT:RXRA
Gene-based: RELATED:NR2B1
Other: EXACT:nuclear receptor subfamily 2 group B member 1 | retinoid X receptor alpha
  Definition"A protein that is a translation product of the human RXRA gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:610
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000014372

retinoic acid receptor RXR-alpha

RXRA


"A protein that is a translation product of the human RXRA gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P19793

retinoic acid receptor RXR-alpha (human)

hRXRA


"A retinoic acid receptor RXR-alpha that is encoded in the genome of human." [PRO:DNx, UniProtKB:P19793]


organism-sequence



PR:P19793-1

retinoic acid receptor RXR-alpha isoform 1 (human)

hRXRA/iso:1


"A retinoic acid receptor RXR-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19793-1." [PRO:DNx, UniProtKB:P19793]


organism-sequence



PR:P19793-2

retinoic acid receptor RXR-alpha isoform h2 (human)

hRXRA/iso:h2


"A retinoic acid receptor RXR-alpha (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P19793-2." [PRO:DNx, UniProtKB:P19793]


organism-modification



PR:000045705

retinoic acid receptor RXR-alpha phosphorylated 1 (human)

hRXRA/Phos:1


"A retinoic acid receptor RXR-alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-260 of the amino acid sequence represented by UniProtKB:P19793-1. Example: UniProtKB:P19793-1, Ser-260, MOD:00046." [iPTMnet:P19793, PMID:10377179]


organism-modification



PR:000049146

retinoic acid receptor RXR-alpha phosphorylated 2 (human)

hRXRA/Phos:2


"A retinoic acid receptor RXR-alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-21 of the amino acid sequence represented by UniProtKB:P19793. UniProtKB:P19793, Ser-21, MOD:00046." [PRO:DNx, Reactome:R-HSA-5334811]


organism-modification



PR:000064658

retinoic acid receptor RXR-alpha sumoylated 1 (human)

hRXRA/Sumo:1


"A retinoic acid receptor RXR-alpha (human) that has been sumoylated on the residue at the position equivalent to Lys-108 of the amino acid sequence represented by UniProtKB:P19793-1. Example: UniProtKB:P19793-1, Lys-108, MOD:01149." [PRO:DNx, Reactome:R-HSA-4341130]


organism-modification



PR:000078553

retinoic acid receptor RXR-alpha phosphorylated 3 (human)

hRXRA/Phos:3


"A retinoic acid receptor RXR-alpha (human) that has been phosphorylated on the residue at the position equivalent to Ser-88 of the amino acid sequence represented by UniProtKB:P19793-1. Example: UniProtKB:P19793-1, Ser-88, MOD:00046." [IEDB_epitope:1373893, PRO:DNx]


organism-gene



PR:P28700

retinoic acid receptor RXR-alpha (mouse)

mRXRA


"A retinoic acid receptor RXR-alpha that is encoded in the genome of mouse." [OMA:P28700, PRO:DNx]


organism-sequence



PR:P28700-1

retinoic acid receptor RXR-alpha isoform 1 (mouse)

mRXRA/iso:1


"A retinoic acid receptor RXR-alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28700-1." [PMID:1312497, PMID:8954108, PRO:KRC, UniProtKB:P28700]

Yes

organism-sequence



PR:Q6LC96

retinoic acid receptor RXR-alpha isoform 2 (mouse)

mRXRA/iso:2


"A retinoic acid receptor RXR-alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6LC96." [PMID:8954108, PRO:KRC]

Yes

organism-gene



PR:Q05343

retinoic acid receptor RXR-alpha (rat)

rRXRA


"A retinoic acid receptor RXR-alpha that is encoded in the genome of rat." [OMA:Q05343, PRO:DNx]


organism-gene



PR:Q90415

retinoic acid receptor RXR-alpha-B (zebrafish)

z-RXRA


"A retinoic acid receptor RXR-alpha that is encoded in the genome of zebrafish." [PRO:DNx]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P28700-1 mRXRA/iso:1 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:85343; PMID:8954108
PR:Q6LC96 mRXRA/iso:2 acts_upstream_of_or_withinGO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:85343; PMID:8954108