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Protein Ontology report - serine/threonine-protein kinase 4
PR:000015757 - http://purl.obolibrary.org/obo/PR_000015757
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000015757   
  PRO nameserine/threonine-protein kinase 4 
  Synonyms
PRO-Short-label: EXACT:STK4
Gene-based: RELATED:KRS2 | MST1
Other: EXACT:mammalian STE20-like protein kinase 1 | MST-1 | serine/threonine-protein kinase Krs-2 | STE20-like kinase MST1
  Definition"A protein that is a translation product of the human STK4 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2225
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000015757

serine/threonine-protein kinase 4

STK4


"A protein that is a translation product of the human STK4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q13043

serine/threonine-protein kinase 4 (human)

hSTK4


"A serine/threonine-protein kinase 4 that is encoded in the genome of human." [PMID:20171103, PRO:KER]

Yes

organism-sequence



PR:Q13043-1

serine/threonine-protein kinase 4 isoform 1 (human)

hSTK4/iso:1


"A serine/threonine-protein kinase 4 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q13043-2

serine/threonine-protein kinase 4 isoform h2 (human)

hSTK4/iso:h2


"A serine/threonine-protein kinase 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13043-2." [PRO:DNx, UniProtKB:Q13043]


organism-modification



PR:000035909

serine/threonine-protein kinase 4 37kDa subunit (human)

hSTK4/Clv:37kDa


"A serine/threonine-protein kinase 4 37kDa subunit in human. Example: UniProtKB:Q13043-1, 1-326, Thr-183, MOD:00047." [PMID:11278283, PMID:9545236, Reactome:R-HSA-2028682]


organism-modification



PR:000049369

serine/threonine-protein kinase 4 phosphorylated 1 (human)

hSTK4/Phos:1


"A serine/threonine-protein kinase 4 (human) that has been phosphorylated on the residue at the position equivalent to Thr-183 of the amino acid sequence represented by UniProtKB:Q13043. UniProtKB:Q13043, Thr-183, MOD:00047." [PRO:DNx, Reactome:R-HSA-2028258]


organism-modification



PR:000071027

serine/threonine-protein kinase 4 hydroxylated 1 (human)

hSTK4/Hy:1


"A serine/threonine-protein kinase 4 (human) that has been hydroxylated on the residue at the position equivalent to Trp-99 of the amino acid sequence represented by UniProtKB:Q13043-1. Example: UniProtKB:Q13043-1, Trp-99, MOD:01622." [IEDB_epitope:1322667, PRO:DNx]


organism-gene



PR:Q5ZJK4

serine/threonine-protein kinase 4 (chicken)

chick-STK4


"A serine/threonine-protein kinase 4 that is encoded in the genome of chicken." [OMA:Q5ZJK4, PRO:DNx]


organism-gene



PR:Q9C562

CBL-interacting serine/threonine-protein kinase 10 (Arabidopsis thaliana)

At-STK4


"A serine/threonine-protein kinase 4 that is encoded in the genome of Arabidopsis thaliana." [OMA:Q9C562, PRO:DNx]


organism-gene



PR:Q9JI11

serine/threonine-protein kinase 4 (mouse)

mSTK4


"A serine/threonine-protein kinase 4 that is encoded in the genome of mouse." [OMA:Q9JI11, PRO:DNx]


organism-sequence



PR:Q9JI11-1

serine/threonine-protein kinase 4 isoform 1 (mouse)

mSTK4/iso:1


"A serine/threonine-protein kinase 4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q9NB31

serine/threonine-protein kinase cst-1 (worm)

STK4 (worm)


"A serine/threonine-protein kinase 4 that is encoded in the genome of worm." [PRO:DNx]


organism-sequence



PR:Q9NB31-1

serine/threonine-protein kinase cst-1 isoform b (worm)

STK4/iso:b (worm)


"A serine/threonine-protein kinase cst-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NB31-1." [PRO:DNx, UniProtKB:Q9NB31]


organism-sequence



PR:Q9NB31-2

serine/threonine-protein kinase cst-1 isoform a (worm)

STK4/iso:a (worm)


"A serine/threonine-protein kinase cst-1 (worm) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NB31-2." [PRO:DNx, UniProtKB:Q9NB31]


sequence



PR:000040388

serine/threonine-protein kinase 4 isoform 1

STK4/iso:1


"A serine/threonine-protein kinase 4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13043-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:Q13043-1

serine/threonine-protein kinase 4 isoform 1 (human)

hSTK4/iso:1


"A serine/threonine-protein kinase 4 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q9JI11-1

serine/threonine-protein kinase 4 isoform 1 (mouse)

mSTK4/iso:1


"A serine/threonine-protein kinase 4 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000035908

serine/threonine-protein kinase 4 37kDa subunit

STK4/Clv:37kDa


"A serine/threonine-protein kinase 4 that has been processed by proteolytic cleavage and phosphorylated at a residue equivalent to Thr-183 of the amino acid sequence represented by UniProtKB:Q13043. Example: UniProtKB:Q13043, 1-326, Thr-183, MOD:00047." [PMID:11278283, PMID:9545236, PRO:DAN, Reactome:R-HSA-2028682]


organism-modification



PR:000035909

serine/threonine-protein kinase 4 37kDa subunit (human)

hSTK4/Clv:37kDa


"A serine/threonine-protein kinase 4 37kDa subunit in human. Example: UniProtKB:Q13043-1, 1-326, Thr-183, MOD:00047." [PMID:11278283, PMID:9545236, Reactome:R-HSA-2028682]


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q13043 hSTK4 acts_upstream_of_or_withinGO:0006469 negative regulation of protein kinase activity PMID:20171103
GO:0008608 attachment of spindle microtubules to kinetochore PMID:20171103
GO:0032092 positive regulation of protein binding PMID:20171103
GO:0051310 metaphase chromosome alignment PMID:20171103
enablesGO:0005515 protein binding with PR:Q96GD4 AIK2 PMID:20171103