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Protein Ontology report - thrombopoietin
PR:000016318 - http://purl.obolibrary.org/obo/PR_000016318
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000016318   
  PRO namethrombopoietin 
  Synonyms
PRO-Short-label: EXACT:THPO
Gene-based: RELATED:MGDF
Other: EXACT:C-mpl ligand | megakaryocyte colony-stimulating factor | megakaryocyte growth and development factor | ML | myeloproliferative leukemia virus oncogene ligand
  Definition"A protein that is a translation product of the human THPO gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence0                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000016318
thrombopoietin
THPO
"A protein that is a translation product of the human THPO gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P40225
thrombopoietin (human)
hTHPO
"A thrombopoietin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P40225]

organism-sequence


PR:P40225-1
thrombopoietin isoform h1 (human)
hTHPO/iso:h1
"A thrombopoietin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40225-1." [PRO:DNx, UniProtKB:P40225]

organism-sequence


PR:P40225-2
thrombopoietin isoform h2 (human)
hTHPO/iso:h2
"A thrombopoietin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40225-2." [PRO:DNx, UniProtKB:P40225]

organism-sequence


PR:P40225-3
thrombopoietin isoform h3 (human)
hTHPO/iso:h3
"A thrombopoietin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40225-3." [PRO:DNx, UniProtKB:P40225]

organism-modification


PR:000049443
thrombopoietin, signal peptide removed form (human)
hTHPO/SigPep-
"A thrombopoietin (human) that has had the signal peptide removed. UniProtKB:P40225, 22-353." [PRO:DNx, Reactome:R-HSA-443917]

organism-modification


PR:000056500
thrombopoietin N-glycosylated 1 (human)
hTHPO/NGlyco:1
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G00227RN. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G00227RN." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056501
thrombopoietin N-glycosylated 2 (human)
hTHPO/NGlyco:2
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G00800WJ. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G00800WJ." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056502
thrombopoietin N-glycosylated 3 (human)
hTHPO/NGlyco:3
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G01817YC. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G01817YC." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056503
thrombopoietin N-glycosylated 4 (human)
hTHPO/NGlyco:4
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G14389GM. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G14389GM." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056504
thrombopoietin N-glycosylated 5 (human)
hTHPO/NGlyco:5
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G16265MV. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G16265MV." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056505
thrombopoietin N-glycosylated 6 (human)
hTHPO/NGlyco:6
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G17689DH. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G17689DH." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056506
thrombopoietin N-glycosylated 7 (human)
hTHPO/NGlyco:7
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G44444MB. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G44444MB." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056507
thrombopoietin N-glycosylated 8 (human)
hTHPO/NGlyco:8
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G47058MH. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G47058MH." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056508
thrombopoietin N-glycosylated 9 (human)
hTHPO/NGlyco:9
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G56501FP. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G56501FP." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056509
thrombopoietin N-glycosylated 10 (human)
hTHPO/NGlyco:10
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G57789QC. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G57789QC." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056510
thrombopoietin N-glycosylated 11 (human)
hTHPO/NGlyco:11
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G90352XZ. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G90352XZ." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-modification


PR:000056511
thrombopoietin N-glycosylated 12 (human)
hTHPO/NGlyco:12
"A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G94531EZ. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G94531EZ." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]

organism-gene


PR:P40226
thrombopoietin (mouse)
mTHPO
"A thrombopoietin that is encoded in the genome of mouse." [OMA:P40226, PRO:DNx]

organism-sequence


PR:P40226-1
thrombopoietin isoform m1 (mouse)
mTHPO/iso:m1
"A thrombopoietin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40226-1." [PRO:DNx, UniProtKB:P40226]

organism-sequence


PR:P40226-2
thrombopoietin isoform m2 (mouse)
mTHPO/iso:m2
"A thrombopoietin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40226-2." [PRO:DNx, UniProtKB:P40226]

organism-gene


PR:P49745
thrombopoietin (rat)
rTHPO
"A thrombopoietin that is encoded in the genome of rat." [OMA:P49745, PRO:DNx]

organism-gene


PR:Q6IYE9
thrombopoietin (chicken)
chick-THPO
"A thrombopoietin that is encoded in the genome of chicken." [PANTHER:PTHR10560:SF0, PRO:DNx]

modification


PR:000021665
thrombopoietin, signal peptide removed form
THPO/SigPep-
"A thrombopoietin that has had the signal peptide removed." [PRO:DNx]

organism-modification


PR:000049443
thrombopoietin, signal peptide removed form (human)
hTHPO/SigPep-
"A thrombopoietin (human) that has had the signal peptide removed. UniProtKB:P40225, 22-353." [PRO:DNx, Reactome:R-HSA-443917]