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Protein Ontology report - TP53-binding protein 1
PR:000016558 - http://purl.obolibrary.org/obo/PR_000016558
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000016558   
  PRO nameTP53-binding protein 1 
  Synonyms
PRO-Short-label: EXACT:TP53BP1
Gene-based: RELATED:Trp53bp1
Other: EXACT:53BP1 | p53-binding protein 1 | p53BP1 | tumor suppressor p53-binding protein 1
  Definition"A protein that is a translation product of the human TP53BP1 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence0                                                  Organism-Sequence 6                                        
         Modification0                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000016558

TP53-binding protein 1

TP53BP1


"A protein that is a translation product of the human TP53BP1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:000029999

DNA repair protein crb2 (Schizosaccharomyces pombe)

Spom-crb2


"A TP53-binding protein 1 that is encoded in the genome of Schizosaccharomyces pombe." [PRO:DAN]


organism-gene



PR:P87074

DNA repair protein crb2 (Schizosaccharomyces pombe 972h-)

Spom972h-TP53BP1


"A TP53-binding protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]


organism-modification



PR:000037316

DNA repair protein crb2 phosphorylated 1 (Schizosaccharomyces pombe)

Spom-TP53BP1/Phos:1


"A DNA repair protein crb2 (Schizosaccharomyces pombe) that is phosphorylated on two Thr residues in CDK consensus TP motifs, and a Thr in the motif VPETV. Example: UniProtKB:P87074, Thr-187/Thr-215/Thr-235, MOD:00047." [PMID:24074952, PomBase:AL]


Yes
organism-modification



PR:000037503

DNA repair protein crb2 phosphorylated 2 (Schizosaccharomyces pombe)

Spom-rhp9/Phos:2


"A DNA repair protein crb2 (Schizosaccharomyces pombe) that is phosphorylated at two conserved SQ/TQ motifs in the N-terminal region. Example: UniProtKB:P87074, Thr-73, MOD:00047|Ser-80, MOD:00046." [PMID:22792081, PomBase:MAH]


organism-gene



PR:P70399

TP53-binding protein 1 (mouse)

mTP53BP1


"A TP53-binding protein 1 that is encoded in the genome of mouse." [OMA:P70399, PRO:DNx]


organism-sequence



PR:P70399-1

TP53-binding protein 1 isoform m1 (mouse)

mTP53BP1/iso:m1


"A TP53-binding protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70399-1." [PRO:DNx, UniProtKB:P70399]


organism-sequence



PR:P70399-5

TP53-binding protein 1 isoform m2 (mouse)

mTP53BP1/iso:m2


"A TP53-binding protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70399-5." [PRO:DNx, UniProtKB:P70399]


organism-sequence



PR:P70399-6

TP53-binding protein 1 isoform m3 (mouse)

mTP53BP1/iso:m3


"A TP53-binding protein 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P70399-6." [PRO:DNx, UniProtKB:P70399]


organism-gene



PR:P87074

DNA repair protein crb2 (Schizosaccharomyces pombe 972h-)

Spom972h-TP53BP1


"A TP53-binding protein 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]


organism-gene



PR:Q12888

TP53-binding protein 1 (human)

hTP53BP1


"A TP53-binding protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q12888]


organism-sequence



PR:Q12888-1

TP53-binding protein 1 isoform h1 (human)

hTP53BP1/iso:h1


"A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-1." [PRO:DNx, UniProtKB:Q12888]


organism-sequence



PR:Q12888-2

TP53-binding protein 1 isoform h2 (human)

hTP53BP1/iso:h2


"A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-2." [PRO:DNx, UniProtKB:Q12888]


organism-sequence



PR:Q12888-3

TP53-binding protein 1 isoform h3 (human)

hTP53BP1/iso:h3


"A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-3." [PRO:DNx, UniProtKB:Q12888]


organism-modification



PR:000045893

TP53-binding protein 1 phosphorylated 1 (human)

hTP53BP1/Phos:1


"A TP53-binding protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-1219 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Ser-1219, MOD:00046." [iPTMnet:Q12888, PMID:18996087]


organism-modification



PR:000049527

TP53-binding protein 1 phosphorylated 2 (human)

hTP53BP1/Phos:2


"A TP53-binding protein 1 (human) that has been post-translationally modified to include phosphoserine at positions 25 and 1778 of the amino acid sequence represented by UniProtKB:Q12888. UniProtKB:Q12888, Ser-25/Ser-1778, MOD:00046." [PRO:DNx, Reactome:R-HSA-5683418]


organism-modification



PR:000049528

TP53-binding protein 1 sumoylated form (human)

hTP53BP1/SumoLys+


"A TP53-binding protein 1 (human) that includes at least one sumoylated lysine. UniProtKB:Q12888, MOD:01149." [PRO:DNx, Reactome:R-HSA-2997591]


organism-modification



PR:000066677

TP53-binding protein 1 citrullinated 1 (human)

hTP53BP1/Cit:1


"A TP53-binding protein 1 (human) that has been citrullinated on the residue at the position equivalent to Arg-1956 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Arg-1956, MOD:00219." [IEDB_epitope:1816365, PRO:DNx]


organism-modification



PR:000069180

TP53-binding protein 1 methylated 1 (human)

hTP53BP1/Me:1


"A TP53-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-1796 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Cys-1796, MOD:00660." [IEDB_epitope:1035082, PRO:DNx]


organism-modification



PR:000069634

TP53-binding protein 1 methylated 2 (human)

hTP53BP1/Me:2


"A TP53-binding protein 1 (human) that has been methylated on the residue at the position equivalent to Cys-1825 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Cys-1825, MOD:00660." [IEDB_epitope:1021484, PRO:DNx]


organism-modification



PR:000073045

TP53-binding protein 1 deaminated 1 (human)

hTP53BP1/Deam:1


"A TP53-binding protein 1 (human) that has been deaminated on the residue at the position equivalent to Asn-683 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Asn-683, MOD:00684." [IEDB_epitope:1991799, PRO:DNx]


organism-modification



PR:000073493

TP53-binding protein 1 deaminated 2 (human)

hTP53BP1/Deam:2


"A TP53-binding protein 1 (human) that has been deaminated on the residue at the position equivalent to Asn-115 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Asn-115, MOD:00684." [IEDB_epitope:1362599, PRO:DNx]


organism-modification



PR:000083519

TP53-binding protein 1 deaminated 3 (human)

hTP53BP1/Deam:3


"A TP53-binding protein 1 (human) that has been deaminated on the residue at the position equivalent to Gln-1180 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Gln-1180, MOD:00685." [IEDB_epitope:1991824, PRO:DNx]


organism-gene



PR:Q7JKP6

protein hsr-9 (worm)

TP53BP1 (worm)


"A TP53-binding protein 1 that is encoded in the genome of worm." [PANTHER:PTHR15321:SF0, PRO:DNx]


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TP53BP1 forms found in complexes   

TP53BP1 Component
Complexes
PR:000037316 Spom-TP53BP1/Phos:1 PR:000037317 Crb2 dimer (Schizosaccharomyces pombe)