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Protein Ontology report - triggering receptor expressed on myeloid cells 2
PR:000016626 - http://purl.obolibrary.org/obo/PR_000016626
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000016626   
  PRO nametriggering receptor expressed on myeloid cells 2 
  Synonyms
PRO-Short-label: EXACT:TREM2
Gene-based: RELATED:Trem2a | Trem2b | Trem2c
Other: EXACT:TREM-2 | triggering receptor expressed on monocytes 2
  Definition"A protein that is a translation product of the human TREM2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 2                                        
         Sequence0                                                  Organism-Sequence 56                                        
         Modification0                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000016626 triggering receptor expressed on myeloid cells 2
TREM2

organism-gene


PR:Q99NH8 triggering receptor expressed on myeloid cells 2 (mouse)
mTREM2

organism-sequence


PR:Q99NH8-1 triggering receptor expressed on myeloid cells 2 isoform m1 (mouse)
mTREM2/iso:m1

organism-sequence


PR:Q99NH8-2 triggering receptor expressed on myeloid cells 2 isoform m2 (mouse)
mTREM2/iso:m2

organism-gene


PR:Q9NZC2 triggering receptor expressed on myeloid cells 2 (human)
hTREM2

organism-sequence


PR:000036989 triggering receptor expressed on myeloid cells 2 sequence variant (human)
hTREM2/var+

organism-sequence


PR:000044564 triggering receptor expressed on myeloid cells 2 sequence variant A105T (human)
hTREM2/var:A105T

organism-sequence


PR:000044565 triggering receptor expressed on myeloid cells 2 sequence variant A105V (human)
hTREM2/var:A105V

organism-sequence


PR:000044566 triggering receptor expressed on myeloid cells 2 sequence variant A130S (human)
hTREM2/var:A130S

organism-sequence


PR:000044567 triggering receptor expressed on myeloid cells 2 sequence variant A192T (human)
hTREM2/var:A192T

organism-sequence


PR:000044568 triggering receptor expressed on myeloid cells 2 sequence variant A196T (human)
hTREM2/var:A196T

organism-sequence


PR:000044569 triggering receptor expressed on myeloid cells 2 sequence variant A28V (human)
hTREM2/var:A28V

organism-sequence


PR:000044570 triggering receptor expressed on myeloid cells 2 sequence variant D134G (human)
hTREM2/var:D134G
Yes
organism-sequence


PR:000044571 triggering receptor expressed on myeloid cells 2 sequence variant D39E (human)
hTREM2/var:D39E

organism-sequence


PR:000044572 triggering receptor expressed on myeloid cells 2 sequence variant D39G (human)
hTREM2/var:D39G

organism-sequence


PR:000044573 triggering receptor expressed on myeloid cells 2 sequence variant D86V (human)
hTREM2/var:D86V

organism-sequence


PR:000044574 triggering receptor expressed on myeloid cells 2 sequence variant D87N (human)
hTREM2/var:D87N

organism-sequence


PR:000044576 triggering receptor expressed on myeloid cells 2 sequence variant E151K (human)
hTREM2/var:E151K

organism-sequence


PR:000044577 triggering receptor expressed on myeloid cells 2 sequence variant G17E (human)
hTREM2/var:G17E

organism-sequence


PR:000044578 triggering receptor expressed on myeloid cells 2 sequence variant G45E (human)
hTREM2/var:G45E

organism-sequence


PR:000044579 triggering receptor expressed on myeloid cells 2 sequence variant G58A (human)
hTREM2/var:G58A

organism-sequence


PR:000044580 triggering receptor expressed on myeloid cells 2 sequence variant H157Y (human)
hTREM2/var:H157Y

organism-sequence


PR:000044581 triggering receptor expressed on myeloid cells 2 sequence variant H215Q (human)
hTREM2/var:H215Q

organism-sequence


PR:000044582 triggering receptor expressed on myeloid cells 2 sequence variant H43Y (human)
hTREM2/var:H43Y

organism-sequence


PR:000044583 triggering receptor expressed on myeloid cells 2 sequence variant K186N (human)
hTREM2/var:K186N
Yes
organism-sequence


PR:000044584 triggering receptor expressed on myeloid cells 2 sequence variant L211P (human)
hTREM2/var:L211P

organism-sequence


PR:000044585 triggering receptor expressed on myeloid cells 2 sequence variant L72V (human)
hTREM2/var:L72V

organism-sequence


PR:000044587 triggering receptor expressed on myeloid cells 2 sequence variant N68K (human)
hTREM2/var:N68K

organism-sequence


PR:000044589 triggering receptor expressed on myeloid cells 2 sequence variant R136Q (human)
hTREM2/var:R136Q

organism-sequence


PR:000044590 triggering receptor expressed on myeloid cells 2 sequence variant R136W (human)
hTREM2/var:R136W

organism-sequence


PR:000044591 triggering receptor expressed on myeloid cells 2 sequence variant R47C (human)
hTREM2/var:R47C

organism-sequence


PR:000044592 triggering receptor expressed on myeloid cells 2 sequence variant R47H (human)
hTREM2/var:R47H

organism-sequence


PR:000044593 triggering receptor expressed on myeloid cells 2 sequence variant R52H (human)
hTREM2/var:R52H

organism-sequence


PR:000044594 triggering receptor expressed on myeloid cells 2 sequence variant R62C (human)
hTREM2/var:R62C

organism-sequence


PR:000044595 triggering receptor expressed on myeloid cells 2 sequence variant R62H (human)
hTREM2/var:R62H

organism-sequence


PR:000044596 triggering receptor expressed on myeloid cells 2 sequence variant R98W (human)
hTREM2/var:R98W

organism-sequence


PR:000044597 triggering receptor expressed on myeloid cells 2 sequence variant S116C (human)
hTREM2/var:S116C

organism-sequence


PR:000044598 triggering receptor expressed on myeloid cells 2 sequence variant S162R (human)
hTREM2/var:S162R

organism-sequence


PR:000044599 triggering receptor expressed on myeloid cells 2 sequence variant S16F (human)
hTREM2/var:S16F

organism-sequence


PR:000044600 triggering receptor expressed on myeloid cells 2 sequence variant S31F (human)
hTREM2/var:S31F

organism-sequence


PR:000044601 triggering receptor expressed on myeloid cells 2 sequence variant T223I (human)
hTREM2/var:T223I

organism-sequence


PR:000044602 triggering receptor expressed on myeloid cells 2 sequence variant T66M (human)
hTREM2/var:T66M

organism-sequence


PR:000044603 triggering receptor expressed on myeloid cells 2 sequence variant T96K (human)
hTREM2/var:T96K

organism-sequence


PR:000044604 triggering receptor expressed on myeloid cells 2 sequence variant V126G (human)
hTREM2/var:V126G
Yes
organism-sequence


PR:000044605 triggering receptor expressed on myeloid cells 2 sequence variant V27M (human)
hTREM2/var:V27M

organism-sequence


PR:000044606 triggering receptor expressed on myeloid cells 2 sequence variant W198* (human)
hTREM2/var:W198*

organism-sequence


PR:000044607 triggering receptor expressed on myeloid cells 2 sequence variant W44* (human)
hTREM2/var:W44*
Yes
organism-sequence


PR:000044608 triggering receptor expressed on myeloid cells 2 sequence variant W50C (human)
hTREM2/var:W50C
Yes
organism-sequence


PR:000044609 triggering receptor expressed on myeloid cells 2 sequence variant W78* (human)
hTREM2/var:W78*
Yes
organism-sequence


PR:000044610 triggering receptor expressed on myeloid cells 2 sequence variant Y38C (human)
hTREM2/var:Y38C

organism-sequence


PR:000044613 triggering receptor expressed on myeloid cells 2 isoform h2 sequence variant W191* (human)
hTREM2/iso:h2/var:W191*

organism-sequence


PR:000044614 triggering receptor expressed on myeloid cells 2 isoform h2 sequence variant E202D (human)
hTREM2/iso:h2/var:E202D

organism-sequence


PR:000044615 triggering receptor expressed on myeloid cells 2 isoform h2 sequence variant G219C (human)
hTREM2/iso:h2/var:G219C

organism-sequence


PR:000044616 triggering receptor expressed on myeloid cells 2 isoform h2 sequence variant L205P (human)
hTREM2/iso:h2/var:L205P

organism-sequence


PR:000044617 triggering receptor expressed on myeloid cells 2 isoform h2 sequence variant S183C (human)
hTREM2/iso:h2/var:S183C

organism-sequence


PR:000044618 triggering receptor expressed on myeloid cells 2 isoform h2 sequence variant W200C (human)
hTREM2/iso:h2/var:W200C

organism-sequence


PR:Q9NZC2-1 triggering receptor expressed on myeloid cells 2 isoform h1 (human)
hTREM2/iso:h1

organism-sequence


PR:Q9NZC2-2 triggering receptor expressed on myeloid cells 2 isoform h2 (human)
hTREM2/iso:h2

organism-sequence


PR:Q9NZC2-3 triggering receptor expressed on myeloid cells 2 isoform h3 (human)
hTREM2/iso:h3

organism-modification


PR:000049538 triggering receptor expressed on myeloid cells 2, signal peptide removed form (human)
hTREM2/SigPep-

organism-modification


PR:000085300 triggering receptor expressed on myeloid cells 2 deaminated 1 (human)
hTREM2/Deam:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000044570 hTREM2/var:D134G
Example: UniProtKB:Q9NZC2-1, Asp-134, CHEBI:29947		 associated_with_disease_progressionDO:0090112 Nasu-Hakola disease Alzforum:trem2-d134g
PR:000044583 hTREM2/var:K186N
Example: UniProtKB:Q9NZC2-1, Lys-186, CHEBI:50347		 associated_with_disease_progressionDO:0090112 Nasu-Hakola disease Alzforum:trem2-k186n
PR:000044604 hTREM2/var:V126G
Example: UniProtKB:Q9NZC2-1, Val-126, CHEBI:29947		 associated_with_disease_progressionDO:0090112 Nasu-Hakola disease Alzforum:trem2-v126g
PR:000044607 hTREM2/var:W44*
UniProtKB:Q9NZC2, 1-43		 associated_with_disease_progressionDO:0090112 Nasu-Hakola disease Alzforum:trem2-w44x
PR:000044608 hTREM2/var:W50C
UniProtKB:Q9NZC2, Trp-50, CHEBI:29950		 associated_with_disease_progressionDO:0090112 Nasu-Hakola disease Alzforum:trem2-w50c
PR:000044609 hTREM2/var:W78*
UniProtKB:Q9NZC2, 1-77		 associated_with_disease_progressionDO:0090112 Nasu-Hakola disease Alzforum:trem2-w78x