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Protein Ontology report - tuberin
PR:000016709 - http://purl.obolibrary.org/obo/PR_000016709
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000016709   
  PRO nametuberin 
  Synonyms
PRO-Short-label: EXACT:TSC2
Gene-based: RELATED:TSC4
Other: EXACT:tuberous sclerosis 2 protein | tuberous sclerosis 2 protein homolog
  Definition"A protein that is a translation product of the human TSC2 gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence1                                                  Organism-Sequence 20                                        
         Modification0                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000016709
tuberin
TSC2
"A protein that is a translation product of the human TSC2 gene or a 1:1 ortholog thereof." [PRO:DNx]

organism-gene


PR:P49815
tuberin (human)
hTSC2
"A tuberin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-1
tuberin isoform 1 (human)
hTSC2/iso:1
"A tuberin isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-2
tuberin isoform h2 (human)
hTSC2/iso:h2
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-2." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-3
tuberin isoform h3 (human)
hTSC2/iso:h3
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-3." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-4
tuberin isoform h4 (human)
hTSC2/iso:h4
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-4." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-5
tuberin isoform h5 (human)
hTSC2/iso:h5
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-5." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-6
tuberin isoform h6 (human)
hTSC2/iso:h6
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-6." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-7
tuberin isoform h7 (human)
hTSC2/iso:h7
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-7." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:P49815-8
tuberin isoform h8 (human)
hTSC2/iso:h8
"A tuberin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-8." [PRO:DNx, UniProtKB:P49815]

organism-modification


PR:000045806
tuberin phosphorylated 1 (human)
hTSC2/Phos:1
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Tyr-1571 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Tyr-1571, MOD:00048." [iPTMnet:P49815, PMID:11290735]

organism-modification


PR:000049554
tuberin phosphorylated 2 (human)
hTSC2/Phos:2
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Ser-1387 of the amino acid sequence represented by UniProtKB:P49815. UniProtKB:P49815, Ser-1387, MOD:00046." [PRO:DNx, Reactome:R-HSA-3132769]

organism-modification


PR:000049555
tuberin phosphorylated 3 (human)
hTSC2/Phos:3
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Ser-939, and phosphothreonine at position 1462 of the amino acid sequence represented by UniProtKB:P49815. UniProtKB:P49815, Ser-939, MOD:00046|Thr-1462, MOD:00047." [PRO:DNx, Reactome:R-HSA-199484]

organism-modification


PR:000049556
tuberin phosphorylated 4 (human)
hTSC2/Phos:4
"A tuberin (human) that has been post-translationally modified to include phosphoserine at positions 939 and 1130, and phosphothreonine at position 1462 of the amino acid sequence represented by UniProtKB:P49815. UniProtKB:P49815, Ser-939/Ser-1130, MOD:00046|Thr-1462, MOD:00047." [PRO:DNx, Reactome:R-HSA-165164]

organism-modification


PR:000069359
tuberin phosphorylated 5 (human)
hTSC2/Phos:5
"A tuberin (human) that has been phosphorylated on the residue at the position equivalent to Thr-1059 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Thr-1059, MOD:00047." [IEDB_epitope:2148836, PRO:DNx]

organism-modification


PR:000073763
tuberin cysteinylated 1 (human)
hTSC2/Cyst:1
"A tuberin (human) that has been cysteinylated on the residue at the position equivalent to Cys-65 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-65, MOD:00765." [IEDB_epitope:776947, PRO:DNx]

organism-modification


PR:000079487
tuberin methylated 1 (human)
hTSC2/Me:1
"A tuberin (human) that has been methylated on the residue at the position equivalent to Cys-1755 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-1755, MOD:00660." [IEDB_epitope:1045055, PRO:DNx]

organism-modification


PR:000081087
tuberin cysteinylated 2 (human)
hTSC2/Cyst:2
"A tuberin (human) that has been cysteinylated on the residue at the position equivalent to Cys-227 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-227, MOD:00765." [IEDB_epitope:1585125, PRO:DNx]

organism-modification


PR:000082494
tuberin methylated 2 (human)
hTSC2/Me:2
"A tuberin (human) that has been methylated on the residue at the position equivalent to Cys-65 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Cys-65, MOD:00660." [IEDB_epitope:1043823, PRO:DNx]

organism-modification


PR:000082517
tuberin deaminated 1 (human)
hTSC2/Deam:1
"A tuberin (human) that has been deaminated on the residue at the position equivalent to Gln-572 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Gln-572, MOD:00685." [IEDB_epitope:1341913, PRO:DNx]

organism-modification


PR:000083425
tuberin deaminated 2 (human)
hTSC2/Deam:2
"A tuberin (human) that has been deaminated on the residue at the position equivalent to Gln-220 of the amino acid sequence represented by UniProtKB:P49815-1. Example: UniProtKB:P49815-1, Gln-220, MOD:00685." [IEDB_epitope:1976063, PRO:DNx]

organism-gene


PR:P49816
tuberin (rat)
rTSC2
"A tuberin that is encoded in the genome of rat." [OMA:P49816, PRO:DNx]

organism-sequence


PR:P49816-1
tuberin isoform r1 (rat)
rTSC2/iso:r1
"A tuberin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49816-1." [PRO:DNx, UniProtKB:P49816]

organism-sequence


PR:P49816-2
tuberin isoform r2 (rat)
rTSC2/iso:r2
"A tuberin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49816-2." [PRO:DNx, UniProtKB:P49816]

organism-sequence


PR:P49816-3
tuberin isoform r3 (rat)
rTSC2/iso:r3
"A tuberin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49816-3." [PRO:DNx, UniProtKB:P49816]

organism-sequence


PR:P49816-4
tuberin isoform r4 (rat)
rTSC2/iso:r4
"A tuberin (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49816-4." [PRO:DNx, UniProtKB:P49816]

organism-gene


PR:Q61037
tuberin (mouse)
mTSC2
"A tuberin that is encoded in the genome of mouse." [OMA:Q61037, PRO:DNx]

organism-sequence


PR:Q3UHB2
tuberin isoform 1 (mouse)
mTSC2/iso:1
"A tuberin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]

organism-sequence


PR:Q61037-1
tuberin isoform G (mouse)
mTSC2/iso:G
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-1." [PMID:777431, PRO:HJD, UniProtKB:Q61037]

organism-sequence


PR:Q61037-2
tuberin isoform A (mouse)
mTSC2/iso:A
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-2." [PMID:8777431, PRO:HJD, UniProtKB:Q61037]

organism-sequence


PR:Q61037-3
tuberin isoform B (mouse)
mTSC2/iso:B
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-3." [PMID:8777431, PRO:HJD, UniProtKB:Q61037]

organism-sequence


PR:Q61037-4
tuberin isoform C (mouse)
mTSC2/iso:C
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-4." [PMID:8777431, PRO:HJD, UniProtKB:Q61037]

organism-sequence


PR:Q61037-5
tuberin isoform D (mouse)
mTSC2/iso:D
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-5." [PMID:8777431, PRO:HJD, UniProtKB:Q61037]

organism-sequence


PR:Q61037-6
tuberin isoform E (mouse)
mTSC2/iso:E
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-6." [PMID:8777431, PRO:HJD, UniProtKB:Q61037]

organism-sequence


PR:Q61037-7
tuberin isoform F (mouse)
mTSC2/iso:F
"A tuberin (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q61037-7." [PMID:8777431, PRO:HJD, UniProtKB:Q61037]

organism-gene


PR:Q9UUG9
tuberous sclerosis 2 protein homolog (Schizosaccharomyces pombe 972h-)
Spom972h-TSC2
"A tuberin that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR10063:SF1, PRO:DNx]

sequence


PR:000026792
tuberin isoform 1
TSC2/iso:1
"A tuberin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P49815-1 or a 1:1 ortholog thereof." [PRO:CNA]

organism-sequence


PR:P49815-1
tuberin isoform 1 (human)
hTSC2/iso:1
"A tuberin isoform 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P49815]

organism-sequence


PR:Q3UHB2
tuberin isoform 1 (mouse)
mTSC2/iso:1
"A tuberin isoform 1 that is encoded in the genome of mouse." [PRO:CNA]