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Protein Ontology report - thymidylate synthase
PR:000016876 - http://purl.obolibrary.org/obo/PR_000016876
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000016876   
  PRO namethymidylate synthase 
  Synonyms
PRO-Short-label: EXACT:TYMS
Gene-based: RELATED:OK/SW-cl.29 | TS
Other: EXACT:TSase
RELATED:thyA
  Definition"A protein that is a translation product of the human TYMS gene or a 1:1 ortholog thereof." [PRO:DNx] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 9                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2642
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000016876

thymidylate synthase

TYMS


"A protein that is a translation product of the human TYMS gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O76511

thymidylate synthase (fruit fly)

fly-TYMS


"A thymidylate synthase that is encoded in the genome of fruit fly." [OMA:O76511, PRO:DNx]


organism-gene



PR:P04818

thymidylate synthase (human)

hTYMS


"A thymidylate synthase that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04818]


organism-sequence



PR:P04818-1

thymidylate synthase isoform h1 (human)

hTYMS/iso:h1


"A thymidylate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04818-1." [PRO:DNx, UniProtKB:P04818]


organism-sequence



PR:P04818-2

thymidylate synthase isoform h2 (human)

hTYMS/iso:h2


"A thymidylate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04818-2." [PRO:DNx, UniProtKB:P04818]


organism-sequence



PR:P04818-3

thymidylate synthase isoform h3 (human)

hTYMS/iso:h3


"A thymidylate synthase (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04818-3." [PRO:DNx, UniProtKB:P04818]


organism-modification



PR:000049572

thymidylate synthase, initiator methionine removed form (human)

hTYMS/InitMet-


"A thymidylate synthase (human) that has had the initiator methionine removed. UniProtKB:P04818, 2-313." [PRO:DNx, Reactome:R-HSA-73518]


organism-modification



PR:000068615

thymidylate synthase cysteinylated 1 (human)

hTYMS/Cyst:1


"A thymidylate synthase (human) that has been cysteinylated on the residue at the position equivalent to Cys-210 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Cys-210, MOD:00765." [IEDB_epitope:635461, IEDB_epitope:930974, PRO:DNx]


organism-modification



PR:000070866

thymidylate synthase deaminated 1 (human)

hTYMS/Deam:1


"A thymidylate synthase (human) that has been deaminated on the residue at the position equivalent to Gln-32 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Gln-32, MOD:00685." [IEDB_epitope:1568587, IEDB_epitope:2142445, PRO:DNx]


organism-modification



PR:000072157

thymidylate synthase glutathionylated 1 (human)

hTYMS/SGlt:1


"A thymidylate synthase (human) that has been glutathionylated on the residue at the position equivalent to Cys-210 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Cys-210, MOD:00234." [IEDB_epitope:422611, PRO:DNx]


organism-modification



PR:000072478

thymidylate synthase methylated 1 (human)

hTYMS/Me:1


"A thymidylate synthase (human) that has been methylated on the residue at the position equivalent to Cys-195 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Cys-195, MOD:00660." [IEDB_epitope:1032851, PRO:DNx]


organism-modification



PR:000073812

thymidylate synthase methylated 2 (human)

hTYMS/Me:2


"A thymidylate synthase (human) that has been methylated on the residue at the position equivalent to Cys-210 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Cys-210, MOD:00660." [IEDB_epitope:1008566, IEDB_epitope:1036167, IEDB_epitope:1059921, PRO:DNx]


organism-modification



PR:000079354

thymidylate synthase cysteinylated 2 (human)

hTYMS/Cyst:2


"A thymidylate synthase (human) that has been cysteinylated on the residue at the position equivalent to Cys-43 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Cys-43, MOD:00765." [IEDB_epitope:1572160, IEDB_epitope:1572161, PRO:DNx]


organism-modification



PR:000080079

thymidylate synthase methylated 3 (human)

hTYMS/Me:3


"A thymidylate synthase (human) that has been methylated on the residue at the position equivalent to Cys-199 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Cys-199, MOD:00660." [IEDB_epitope:1004188, PRO:DNx]


organism-modification



PR:000084679

thymidylate synthase deaminated 2 (human)

hTYMS/Deam:2


"A thymidylate synthase (human) that has been deaminated on the residue at the position equivalent to Gln-36 of the amino acid sequence represented by UniProtKB:P04818-1. Example: UniProtKB:P04818-1, Gln-36, MOD:00685." [IEDB_epitope:1323692, PRO:DNx]


organism-gene



PR:P06785

thymidylate synthase (yeast)

yTYMS


"A thymidylate synthase that is encoded in the genome of yeast." [OMA:P06785, PRO:DNx]


organism-gene



PR:P07607

thymidylate synthase (mouse)

mTYMS


"A thymidylate synthase that is encoded in the genome of mouse." [OMA:P07607, PRO:DNx]


organism-sequence



PR:P07607-1

thymidylate synthase isoform 1 (mouse)

mTYMS/iso:1


"A thymidylate synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:P0A884

thymidylate synthase (Escherichia coli K-12)

Ec-TYMS


"A thymidylate synthase that is encoded in the genome of Escherichia coli K-12." [OMA:P0A884, PRO:DNx]


organism-gene



PR:P12461

thymidylate synthase (Candida albicans SC5314)

Calb-TYMS


"A thymidylate synthase that is encoded in the genome of Candida albicans SC5314." [OMA:P12461, PRO:DAN]


organism-gene



PR:P45352

thymidylate synthase (rat)

rTYMS


"A thymidylate synthase that is encoded in the genome of rat." [OMA:P45352, PRO:DNx]


organism-sequence



PR:P45352-1

thymidylate synthase isoform 1 (rat)

rTYMS/iso:1


"A thymidylate synthase isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q2FYK5

thymidylate synthase (Staphylococcus aureus subsp. aureus NCTC 8325)

TYMS (STAA8)


"A thymidylate synthase that is encoded in the genome of Staphylococcus aureus subsp. aureus NCTC 8325." [OMA:Q2FYK5, PRO:DNx]


organism-gene



PR:Q9UTI7

probable thymidylate synthase (Schizosaccharomyces pombe 972h-)

Spom972h-TYMS


"A thymidylate synthase that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PANTHER:PTHR11549:SF2, PRO:DNx]


sequence



PR:000038714

thymidylate synthase isoform 1

TYMS/iso:1


"A thymidylate synthase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07607-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P07607-1

thymidylate synthase isoform 1 (mouse)

mTYMS/iso:1


"A thymidylate synthase isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P45352-1

thymidylate synthase isoform 1 (rat)

rTYMS/iso:1


"A thymidylate synthase isoform 1 that is encoded in the genome of rat." [PRO:DNx]


modification



PR:000021763

thymidylate synthase, initiator methionine removed form

TYMS/InitMet-


"A thymidylate synthase that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000049572

thymidylate synthase, initiator methionine removed form (human)

hTYMS/InitMet-


"A thymidylate synthase (human) that has had the initiator methionine removed. UniProtKB:P04818, 2-313." [PRO:DNx, Reactome:R-HSA-73518]