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Protein Ontology report - protein kinase C beta type, initiator methionine removed form
PR:000018783 - http://purl.obolibrary.org/obo/PR_000018783
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000018783   
  PRO nameprotein kinase C beta type, initiator methionine removed form 
  Synonyms
PRO-Short-label: EXACT:PRKCB/InitMet-
  Definition"A protein kinase C beta type that has had the initiator methionine removed." [PRO:DNx] 
  PRO Categorymodification 
  ParentPR:000003059 protein kinase C beta type
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 7                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000018783
protein kinase C beta type, initiator methionine removed form
PRKCB/InitMet-
"A protein kinase C beta type that has had the initiator methionine removed." [PRO:DNx]

organism-modification


PR:000048913
protein kinase C beta type, initiator methionine removed form (human)
hPRKCB/InitMet-
"A protein kinase C beta type (human) that has had the initiator methionine removed. UniProtKB:P05771, 2-671." [PRO:DNx, Reactome:R-HSA-156467, Reactome:R-HSA-58198]

organism-modification


PR:000048914
protein kinase C beta type, initiator methionine removed phosphorylated 1 (human)
hPRKCB/InitMet-/Phos:1
"A protein kinase C beta type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the amino acid sequence represented by UniProtKB:P05771. UniProtKB:P05771, 2-671, Thr-500, MOD:00047." [PRO:DNx, Reactome:R-HSA-5218728]

organism-modification


PR:000048915
protein kinase C beta type, initiator methionine removed phosphorylated 2 (human)
hPRKCB/InitMet-/Phos:2
"A protein kinase C beta type (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at positions 500 and 642, and phosphoserine at position 661 of the amino acid sequence represented by UniProtKB:P05771. UniProtKB:P05771, 2-671, Thr-500/Thr-642, MOD:00047|Ser-661, MOD:00046." [PRO:DNx, Reactome:R-HSA-5218706, Reactome:R-HSA-5223294]

organism-modification


PR:000049853
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049854
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 1 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:1
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and lacks a phosphothreonine at position 500. UniProtKB:P05771-2, 2-673, Thr-500, PR:000026291." [PMID:8749392, PRO:KER]

organism-modification


PR:000049855
protein kinase C beta type isoform Beta-II, initiator methionine removed phosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/Phos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500 of the activation loop, and phosphothreonine at position 641 and phosphoserine at position 660 of the Pkinase_C domain (Pfam:PF00433). UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046." [PMID:8749392, PRO:KER]
Yes
organism-modification


PR:000049856
protein kinase C beta type isoform Beta-II, initiator methionine removed unphosphorylated 2 (human)
hPRKCB/iso:Beta-II/InitMet-/UnPhos:2
"A protein kinase C beta type isoform Beta-II (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphothreonine at position 500,a phosphothreonine at position 641 and a phosphoserine at position 660. UniProtKB:P05771-2, 2-673, Thr-500/Thr-641/Ser-660, PR:000026291." [PMID:8749392, PRO:KER]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000049853 hPRKCB/iso:Beta-II/InitMet-/Phos:1
UniProtKB:P05771-2, 2-673, Thr-500, MOD:00047		 enablesincreased GO:0004674 protein serine/threonine kinase activity relative to PR:000049854 hPRKCB/iso:Beta-II/InitMet-/UnPhos:1 PMID:8749392
located_inGO:0005737 cytoplasm PMID:9756933
GO:0005886 plasma membrane PMID:9756933
PR:000049855 hPRKCB/iso:Beta-II/InitMet-/Phos:2
UniProtKB:P05771-2, 2-673, Thr-500/Thr-641, MOD:00047|Ser-660, MOD:00046		 acts_upstream_of_or_withinincreased GO:0006468 protein phosphorylation relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:8749392
enablesincreased GO:0001786 phosphatidylserine binding relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9218480
increased GO:0005509 calcium ion binding relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9218480
located_inincreased GO:0005737 cytoplasm relative to PR:000049856 hPRKCB/iso:Beta-II/InitMet-/UnPhos:2 PMID:9756933