back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - TGF-beta 1 sequence variant R218H, signal peptide removed form (human)
PR:000021907 - http://purl.obolibrary.org/obo/PR_000021907
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000021907   
  PRO nameTGF-beta 1 sequence variant R218H, signal peptide removed form (human) 
  Synonyms
PRO-Short-label: EXACT:hTGFB1/var:R218H/SigPep-
PRO-proteoform-std: EXACT:UniProtKB:P01137, 30-390, Arg-218, CHEBI:29979
Other: EXACT:TGF-beta 1 sequence variant 4, signal peptide removed form (human)
  Definition"A TGF-beta 1 sequence variant R218H (human) that has had the signal peptide removed. UniProtKB:P01137, 30-390, Arg-218, CHEBI:29979." [PRO:DAN] 
  PRO Categoryorganism-modification 
  ParentPR:000000401 TGF-beta 1 sequence variant R218H (human)
PR:000049430 transforming growth factor beta-1, signal peptide removed form (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-modification


PR:000021907 TGF-beta 1 sequence variant R218H, signal peptide removed form (human)
hTGFB1/var:R218H/SigPep-

organism-modification


PR:000000627 TGF-beta 1 sequence variant R218H cleaved 1 (human)
hTGFB1/var:R218H/Clv:1
Yes
organism-modification


PR:000000628 TGF-beta 1 sequence variant R218H cleaved 2 (human)
hTGFB1/var:R218H/Clv:2
Yes
Back to top
Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000000627 hTGFB1/var:R218H/Clv:1 PMID:11278244

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005160 transforming growth factor beta receptor bindingPR:000000627 hTGFB1/var:R218H/Clv:1 PMID:11278244
GO:0008083 growth factor activityPR:000000627 hTGFB1/var:R218H/Clv:1 PMID:12493741; PMID:12843182
GO:0042803 protein homodimerization activityPR:000000627 hTGFB1/var:R218H/Clv:1 PMID:11278244

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005615 extracellular spacePR:000000627 hTGFB1/var:R218H/Clv:1 PMID:11278244
SO:0001561 polypeptide_partial_loss_of_functionPR:000000628 hTGFB1/var:R218H/Clv:2 PMID:11278244
SO:0001601 conformational_change_variantPR:000000628 hTGFB1/var:R218H/Clv:2 PMID:11278244