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family
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PR:000021990 |
dual specificity mitogen-activated protein kinase kinase 3/6
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DLEC2/iso:1/SigPep-/GlycoRes+
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"A protein that is a gene product level of the MAP2K3 or the MAP2K6 gene. Members of this class activate phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively." [PIRSF:PIRSF501132]
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gene
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PR:000003282 |
dual specificity mitogen-activated protein kinase kinase 6
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MAP2K6
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"A dual specificity mitogen-activated protein kinase kinase 3/6 that is a translation product of the human MAP2K6 gene or a 1:1 ortholog thereof." [TLR:AMM]
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Yes |
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organism-gene
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PR:P52564 |
dual specificity mitogen-activated protein kinase kinase 6 (human)
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hMAP2K6
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"A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of human." [TLR:AMM, UniProtKB:P52564]
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organism-sequence
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PR:P52564-1 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 (human)
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hMAP2K6/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:P52564-2 |
dual specificity mitogen-activated protein kinase kinase 6 isoform h2 (human)
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hMAP2K6/iso:h2
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"A dual specificity mitogen-activated protein kinase kinase 6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52564-2." [PRO:DNx, UniProtKB:P52564]
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organism-modification
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PR:000045822 |
dual specificity mitogen-activated protein kinase kinase 6 phosphorylated 1 (human)
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hMAP2K6/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 6 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-219 of the amino acid sequence represented by UniProtKB:P52564-1. Example: UniProtKB:P52564-1, Tyr-219, MOD:00048." [iPTMnet:P52564, PMID:17854274]
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organism-modification
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PR:000048299 |
dual specificity mitogen-activated protein kinase kinase 6 phosphorylated 2 (human)
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hMAP2K6/Phos:2
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"A dual specificity mitogen-activated protein kinase kinase 6 (human) that has been phosphorylated on the residue at the position equivalent to Ser-207, and phosphothreonine at position 211 of the amino acid sequence represented by UniProtKB:P52564. UniProtKB:P52564, Ser-207, MOD:00046|Thr-211, MOD:00047." [PRO:DNx, Reactome:R-HSA-206255, Reactome:R-HSA-450258]
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organism-modification
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PR:000068145 |
dual specificity mitogen-activated protein kinase kinase 6 deaminated 1 (human)
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hMAP2K6/Deam:1
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"A dual specificity mitogen-activated protein kinase kinase 6 (human) that has been deaminated on the residue at the position equivalent to Gln-310 of the amino acid sequence represented by UniProtKB:P52564-1. Example: UniProtKB:P52564-1, Gln-310, MOD:00685." [IEDB_epitope:929050, PRO:DNx]
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organism-gene
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PR:P70236 |
dual specificity mitogen-activated protein kinase kinase 6 (mouse)
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mMAP2K6
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"A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of mouse." [OMA:P70236, PRO:DNx]
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organism-sequence
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PR:P70236-1 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 (mouse)
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mMAP2K6/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-gene
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PR:Q9DGE0 |
dual specificity mitogen-activated protein kinase kinase 6 (zebrafish)
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z-MAP2K6
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"A dual specificity mitogen-activated protein kinase kinase 6 that is encoded in the genome of zebrafish." [TLR:AMM]
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sequence
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PR:000021979 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1
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MAP2K6/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 6 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52564-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:P52564-1 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 (human)
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hMAP2K6/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:P70236-1 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 (mouse)
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mMAP2K6/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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modification
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PR:000021980 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 unmodified form
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MAP2K6/iso:1/UnMod
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:CNA]
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Yes |
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modification
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PR:000021992 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 phosphorylated form
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MAP2K6/iso:1/PhosRes+
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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Yes |
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modification
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PR:000021981 |
dual specificity mitogen-activated protein kinase kinase 6 isoform 1 phosphorylated 1
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MAP2K6/iso:1/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 6 isoform 1 phosphorylated form in which the phosphorylation occurs in the activation loop by ubiquitinated TAK1. Example: UniProtKB:P52564-1, Ser-207, MOD:00046|Thr-211, MOD:00047." [PMID:11460167, TLR:AMM]
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gene
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PR:000003284 |
dual specificity mitogen-activated protein kinase kinase 3
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MAP2K3
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"A dual specificity mitogen-activated protein kinase kinase 3/6 that is a translation product of the human MAP2K3 gene or a 1:1 ortholog thereof." [TLR:AMM]
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organism-gene
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PR:O09110 |
dual specificity mitogen-activated protein kinase kinase 3 (mouse)
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mMAP2K3
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"A dual specificity mitogen-activated protein kinase kinase 3 that is encoded in the genome of mouse." [OMA:O09110, PRO:DNx]
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organism-sequence
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PR:O09110-1 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse)
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mMAP2K3/iso:2
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 1 that is encoded in the genome of mouse." [TLR:AMM]
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organism-modification
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PR:000049826 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (mouse)
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mMAP2K3/iso:2/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse) that has been phosphorylated at Ser-218. UniProtKB:O09110-1, Ser-218, MOD:00046." [PMID:21183079, PRO:HJD]
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organism-modification
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PR:000049827 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 2 (mouse)
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mMAP2K3/iso:2/Phos:2
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse) that has been phosphorylated at Ser-218 and Thr-222. UniProtKB:O09110-1, Ser-218, MOD:00046|Thr-222, MOD:00047." [PMID:21183079, PRO:HJD]
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organism-sequence
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PR:O09110-2 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 1 (mouse)
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mMAP2K3/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-gene
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PR:P46734 |
dual specificity mitogen-activated protein kinase kinase 3 (human)
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hMAP2K3
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"A dual specificity mitogen-activated protein kinase kinase 3 that is encoded in the genome of human." [TLR:AMM, UniProtKB:P46734]
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organism-sequence
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PR:P46734-1 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 3 (human)
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hMAP2K3/iso:3
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 1 that is encoded in the genome of human." [TLR:AMM]
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organism-sequence
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PR:P46734-2 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 1 (human)
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hMAP2K3/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000036646 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (human)
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hMAP2K3/iso:2/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 in human. UniProtKB:P46734-2, Ser-189, MOD:00046|Thr-193, MOD:00047." [PMID:8622669, PRO:CNA]
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Yes |
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organism-sequence
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PR:P46734-3 |
dual specificity mitogen-activated protein kinase kinase 3 isoform h2 (human)
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hMAP2K3/iso:h2
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"A dual specificity mitogen-activated protein kinase kinase 3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46734-3." [PRO:DNx, UniProtKB:P46734]
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organism-modification
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PR:000048297 |
dual specificity mitogen-activated protein kinase kinase 3 phosphorylated 1 (human)
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hMAP2K3/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 3 (human) that has been phosphorylated on the residue at the position equivalent to Ser-218, and phosphothreonine at position 222 of the amino acid sequence represented by UniProtKB:P46734. UniProtKB:P46734, Ser-218, MOD:00046|Thr-222, MOD:00047." [PRO:DNx, Reactome:R-HSA-167955, Reactome:R-HSA-450229]
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organism-modification
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PR:000075054 |
dual specificity mitogen-activated protein kinase kinase 3 cysteinylated 1 (human)
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hMAP2K3/Cyst:1
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"A dual specificity mitogen-activated protein kinase kinase 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-227 of the amino acid sequence represented by UniProtKB:P46734-1. Example: UniProtKB:P46734-1, Cys-227, MOD:00765." [IEDB_epitope:928198, PRO:DNx]
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organism-gene
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PR:Q5ZL06 |
uncharacterized protein, MAP2K3 translation product (chicken)
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chick-MAP2K3
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"A dual specificity mitogen-activated protein kinase kinase 3 that is encoded in the genome of chicken." [PRO:DAN]
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sequence
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PR:000021942 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 1
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MAP2K3/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46734-1 or a 1:1 ortholog thereof." [PMID:8900184, TLR:AMM, UniProtKB:P46734-1]
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organism-sequence
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PR:O09110-1 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse)
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mMAP2K3/iso:2
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 1 that is encoded in the genome of mouse." [TLR:AMM]
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organism-modification
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PR:000049826 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (mouse)
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mMAP2K3/iso:2/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse) that has been phosphorylated at Ser-218. UniProtKB:O09110-1, Ser-218, MOD:00046." [PMID:21183079, PRO:HJD]
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organism-modification
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PR:000049827 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 2 (mouse)
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mMAP2K3/iso:2/Phos:2
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 (mouse) that has been phosphorylated at Ser-218 and Thr-222. UniProtKB:O09110-1, Ser-218, MOD:00046|Thr-222, MOD:00047." [PMID:21183079, PRO:HJD]
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organism-sequence
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PR:P46734-1 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 3 (human)
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hMAP2K3/iso:3
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 1 that is encoded in the genome of human." [TLR:AMM]
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sequence
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PR:000021944 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2
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MAP2K3/iso:2
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"A dual specificity mitogen-activated protein kinase kinase 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46734-2 or a 1:1 ortholog thereof." [PMID:7839144, PRO:CNA]
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organism-sequence
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PR:O09110-2 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 1 (mouse)
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mMAP2K3/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-sequence
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PR:P46734-2 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 1 (human)
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hMAP2K3/iso:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000036646 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (human)
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hMAP2K3/iso:2/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 in human. UniProtKB:P46734-2, Ser-189, MOD:00046|Thr-193, MOD:00047." [PMID:8622669, PRO:CNA]
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Yes |
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modification
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PR:000021991 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated form
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MAP2K3/iso:2/PhosRes+
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000021946 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1
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MAP2K3/iso:2/Phos:1
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"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated form that has been activated by dual phosphorylation on threonine and tyrosine residues. Example: UniProtKB:P46734-2, Ser-189, MOD:00046|Thr-193, MOD:00047." [PMID:7839144, PMID:8622669, TLR:AMM]
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organism-modification
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PR:000036646 |
dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 (human)
|
hMAP2K3/iso:2/Phos:1
|
"A dual specificity mitogen-activated protein kinase kinase 3 isoform 2 phosphorylated 1 in human. UniProtKB:P46734-2, Ser-189, MOD:00046|Thr-193, MOD:00047." [PMID:8622669, PRO:CNA]
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Yes |
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