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Protein Ontology report - sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
PR:000022016 - http://purl.obolibrary.org/obo/PR_000022016
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / PAF
  PRO ID
PR:000022016   
  PRO namesphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 
  Synonyms
PRO-Short-label: EXACT:DEGS2/iso:1
  Definition"A sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8R2F2-1 or a 1:1 ortholog thereof." [PMID:11937514, PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000006414 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000022016 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1
DEGS2/iso:1
Yes
organism-sequence


PR:Q6QHC5-1 sphingolipid Delta(4)-desaturase/C4-monooxygenase DES2 isoform 1 (human)
hDEGS2/iso:1

organism-sequence


PR:Q8R2F2-1 sphingolipid Delta(4)-desaturase/C4-hydroxylase DES2 isoform 1 (mouse)
mDEGS2/iso:1
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0006667 sphinganine metabolic processPR:000022016 DEGS2/iso:1 MGI_ref:3694278; PMID:16571104
PR:Q8R2F2-1 mDEGS2/iso:1 MGI_ref:3694278; PMID:16571104
GO:0046513 ceramide biosynthetic processPR:000022016 DEGS2/iso:1 MGI_ref:3694278; PMID:16571104
PR:Q8R2F2-1 mDEGS2/iso:1 MGI_ref:3694278; PMID:16571104

Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0102772 sphingolipid C4-monooxygenase activityPR:000022016 DEGS2/iso:1 MGI_ref:3694278; PMID:16571104
PR:000022016 DEGS2/iso:1 MGI_ref:3694278; PMID:16571104
PR:Q8R2F2-1 mDEGS2/iso:1 MGI_ref:3056825; PMID:15474011
PR:Q8R2F2-1 mDEGS2/iso:1 MGI_ref:3056825; PMID:15474011
PR:Q8R2F2-1 mDEGS2/iso:1 MGI_ref:3056825; PMID:15474011
PR:Q8R2F2-1 mDEGS2/iso:1 MGI_ref:3056825; PMID:15474011