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Protein Ontology report - cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3
PR:000025751 - http://purl.obolibrary.org/obo/PR_000025751
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000025751   
  PRO namecyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 
  Synonyms
PRO-Short-label: EXACT:CDKN1B/iso:1/Phos:3
Other: RELATED:p27 phosphorylated form
  Definition"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain, and phosphorylated by CDK2 on a Thr residue in the C-terminal region. Phosphorylation by CDK2 promotes degradation by the SCF-Skp2 ubiquitin-proteasome pathway. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA, PRO:DAN] 
  PRO Categorymodification 
  ParentPR:000003093 cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
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PRO ID
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Definition
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modification


PR:000025751
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3
CDKN1B/iso:1/Phos:3
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain, and phosphorylated by CDK2 on a Thr residue in the C-terminal region. Phosphorylation by CDK2 promotes degradation by the SCF-Skp2 ubiquitin-proteasome pathway. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA, PRO:DAN]

organism-modification


PR:000025752
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 (human)
hCDKN1B/iso:1/Phos:3
"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 in human. UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA]