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Protein Ontology report - smad2 isoform Long phosphorylated 2 (human) PR:000025935 - http://purl.obolibrary.org/obo/PR_000025935        Complex   Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000025935      PRO name smad2 isoform Long phosphorylated 2 (human)    Synonyms PRO-Short-label: EXACT: hSMAD2/iso:Long/Phos:2 PRO-proteoform-std: NARROW: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046   Definition "A smad2 isoform Long phosphorylated 2 in human. This form is phosphorylated at the N-terminal Px[ST]P motif, multiple Ser and/or Thr residues in the linker region and the SSxS C-terminal motif. Example: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046." [PMID:12193595]    Comment Kinase=("MAPK3"; PR:000026189; Thr-8/Thr-220/Ser-245/Ser-250/Ser-255). Kinase=("TGFBR1"; PR:000025963; Ser-465/Ser-467).    PRO Category organism-modification    Parent PR:000000651 smad2 isoform Long phosphorylated 2 PR:Q15796 mothers against decapentaplegic homolog 2 (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top hSMAD2/iso:Long/Phos:2 forms found in complexes    hSMAD2/iso:Long/Phos:2 Component Complexes PR:000025935 hSMAD2/iso:Long/Phos:2 PR:000025946 smad2-smad4 protein complex 3 (human) Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000025935 hSMAD2/iso:Long/Phos:2 Example: UniProtKB:Q15796-1, Thr-8/Thr-220, MOD:00047|Ser-245/Ser-250/Ser-255/Ser-465/Ser-467, MOD:00046 acts_upstream_of_or_within GO:0006355 regulation of DNA-templated transcription PMID:12193595 GO:0007165 signal transduction PMID:12193595 GO:0060395 SMAD protein signal transduction PMID:12193595 enables GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific PMID:12193595 GO:0003712 transcription coregulator activity PMID:12193595 GO:0046332 SMAD binding PMID:12193595 located_in GO:0005634 nucleus PMID:12193595; PMID:17074053