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Protein Ontology report - translation initiation factor 2 subunit 3/gamma
PR:000026089 - http://purl.obolibrary.org/obo/PR_000026089
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000026089   
  PRO nametranslation initiation factor 2 subunit 3/gamma 
  Definition"A protein that is composed of an N-terminal copy of the Elongation factor Tu GTP binding domain (Pfam:PF00009), followed by a copy of the Elongation factor Tu domain 2 (Pfam:PF03144), and a copy of the Initiation factor eIF2 gamma, C terminal (Pfam:PF09173) domain." [PMID:11927566, PRO:CNA] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene2                                                  Organism-Gene 11                                        
         Sequence1                                                  Organism-Sequence 5                                        
         Modification1                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF003021
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000026089

translation initiation factor 2 subunit 3/gamma

CRHR2/iso:iv-beta


"A protein that is composed of an N-terminal copy of the Elongation factor Tu GTP binding domain (Pfam:PF00009), followed by a copy of the Elongation factor Tu domain 2 (Pfam:PF03144), and a copy of the Initiation factor eIF2 gamma, C terminal (Pfam:PF09173) domain." [PMID:11927566, PRO:CNA]


gene



PR:000007287

eukaryotic translation initiation factor 2 subunit 3, Y-linked

Eif2s3y


"A translation initiation factor 2 subunit 3/gamma that is a translation product of the mouse Eif2s3y gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:C9WPN6

eukaryotic translation initiation factor 2 subunit 3, Y-linked (rat)

rEif2s3y


"A eukaryotic translation initiation factor 2 subunit 3, Y-linked that is encoded in the genome of rat." [OMA:C9WPN6, PRO:DNx]


organism-gene



PR:P32481

eukaryotic translation initiation factor 2 subunit gamma (yeast)

yEif2s3y


"A eukaryotic translation initiation factor 2 subunit 3, Y-linked that is encoded in the genome of yeast." [PRO:CNA]


organism-gene



PR:Q9Z0N2

eukaryotic translation initiation factor 2 subunit 3, Y-linked (mouse)

mEif2s3y


"A eukaryotic translation initiation factor 2 subunit 3, Y-linked that is encoded in the genome of mouse." [PRO:HJD]


Yes
organism-modification



PR:000078102

eukaryotic translation initiation factor 2 subunit 3, Y-linked cysteinylated 1 (mouse)

mEif2s3y/Cyst:1


"A eukaryotic translation initiation factor 2 subunit 3, Y-linked (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-236 of the amino acid sequence represented by UniProtKB:Q9Z0N2. UniProtKB:Q9Z0N2, Cys-236, MOD:00765." [IEDB_epitope:1003948, PRO:DNx]


gene



PR:000026090

eukaryotic translation initiation factor 2 subunit 3, X-linked

Eif2s3x


"A translation initiation factor 2 subunit 3/gamma that is a translation product of the mouse Eif2s3x gene or a 1:1 ortholog thereof." [PRO:CNA]


organism-gene



PR:F1QGW6

eukaryotic translation initiation factor 2 subunit 3 (zebrafish)

z-Eif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of zebrafish." [PRO:CNA]


organism-gene



PR:P41091

eukaryotic translation initiation factor 2 subunit 3 (human)

hEIF2S3


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of human." [OMA:P41091, PRO:DNx]


organism-sequence



PR:P41091-1

eukaryotic translation initiation factor 2 subunit 3 isoform 1 (human)

hEIF2S3/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000047268

eukaryotic translation initiation factor 2 subunit 3, initiator methionine removed form (human)

hEIF2S3/InitMet-


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has had the initiator methionine removed. UniProtKB:P41091, 2-472." [PRO:DNx, Reactome:R-HSA-72514]


organism-modification



PR:000067907

eukaryotic translation initiation factor 2 subunit 3 cysteinylated 1 (human)

hEIF2S3/Cyst:1


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-236 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Cys-236, MOD:00765." [IEDB_epitope:1003948, IEDB_epitope:638813, PRO:DNx]


organism-modification



PR:000073251

eukaryotic translation initiation factor 2 subunit 3 deaminated 1 (human)

hEIF2S3/Deam:1


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been deaminated on the residue at the position equivalent to Gln-212 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Gln-212, MOD:00685." [IEDB_epitope:1568954, PRO:DNx]


organism-modification



PR:000074374

eukaryotic translation initiation factor 2 subunit 3 deaminated 2 (human)

hEIF2S3/Deam:2


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been deaminated on the residue at the position equivalent to Gln-206 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Gln-206, MOD:00685." [IEDB_epitope:1568953, PRO:DNx]


organism-modification



PR:000074494

eukaryotic translation initiation factor 2 subunit 3 methylated 1 (human)

hEIF2S3/Me:1


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been methylated on the residue at the position equivalent to Cys-236 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Cys-236, MOD:00660." [IEDB_epitope:1003947, IEDB_epitope:1003949, IEDB_epitope:1056834, IEDB_epitope:1059770, PRO:DNx]


organism-modification



PR:000077455

eukaryotic translation initiation factor 2 subunit 3 methylated 2 (human)

hEIF2S3/Me:2


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been methylated on the residue at the position equivalent to Cys-348 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Cys-348, MOD:00660." [IEDB_epitope:1020140, PRO:DNx]


organism-modification



PR:000080027

eukaryotic translation initiation factor 2 subunit 3 cysteinylated 2 (human)

hEIF2S3/Cyst:2


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-135 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Cys-135, MOD:00765." [IEDB_epitope:1013737, IEDB_epitope:631496, PRO:DNx]


organism-modification



PR:000084567

eukaryotic translation initiation factor 2 subunit 3 methylated 3 (human)

hEIF2S3/Me:3


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has been methylated on the residue at the position equivalent to Cys-135 of the amino acid sequence represented by UniProtKB:P41091. UniProtKB:P41091, Cys-135, MOD:00660." [IEDB_epitope:1013738, IEDB_epitope:1013739, PRO:DNx]


organism-gene



PR:P81795

eukaryotic translation initiation factor 2 subunit 3, X-linked (rat)

rEif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of rat." [OMA:P81795, PRO:DNx]


organism-sequence



PR:P81795-1

eukaryotic translation initiation factor 2 subunit 3 isoform 1 (rat)

rEif2s3x/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q09130

eukaryotic translation initiation factor 2 subunit gamma (Schizosaccharomyces pombe 972h-)

Spom972h-Eif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:CNA]


organism-gene



PR:Q24208

eukaryotic translation initiation factor 2 subunit 3 (fruit fly)

fly-Eif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of fruit fly." [PRO:CNA]


organism-sequence



PR:Q24208-1

eukaryotic translation initiation factor 2 subunit 3 isoform B (fruit fly)

fly-Eif2s3x/iso:B


"A eukaryotic translation initiation factor 2 subunit 3 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q24208-1." [PRO:DNx, UniProtKB:Q24208]


organism-sequence



PR:Q24208-2

eukaryotic translation initiation factor 2 subunit 3 isoform C (fruit fly)

fly-Eif2s3x/iso:C


"A eukaryotic translation initiation factor 2 subunit 3 (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q24208-2." [PRO:DNx, UniProtKB:Q24208]


organism-gene



PR:Q54XD8

eukaryotic translation initiation factor 2 subunit 3 (Dictyostelium discoideum)

Dicty-Eif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of Dictyostelium discoideum." [PRO:CNA]


organism-gene



PR:Q5ZMS3

eukaryotic translation initiation factor 2 subunit 3 (chicken)

chick-Eif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of chicken." [PRO:CNA]


organism-gene



PR:Q9Z0N1

eukaryotic translation initiation factor 2 subunit 3, X-linked (mouse)

mEif2s3x


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is encoded in the genome of mouse." [PRO:HJD]


Yes
organism-sequence



PR:Q9Z0N1-1

eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 (mouse)

mEif2s3x/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000039407

eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1

Eif2s3x/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P41091-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P41091-1

eukaryotic translation initiation factor 2 subunit 3 isoform 1 (human)

hEIF2S3/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:P81795-1

eukaryotic translation initiation factor 2 subunit 3 isoform 1 (rat)

rEif2s3x/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 that is encoded in the genome of rat." [PRO:DNx]


organism-sequence



PR:Q9Z0N1-1

eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 (mouse)

mEif2s3x/iso:1


"A eukaryotic translation initiation factor 2 subunit 3, X-linked isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000026557

eukaryotic translation initiation factor 2 subunit 3, X-linked, initiator methionine removed form

Eif2s3x/InitMet-


"A eukaryotic translation initiation factor 2 subunit 3, X-linked that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000047268

eukaryotic translation initiation factor 2 subunit 3, initiator methionine removed form (human)

hEIF2S3/InitMet-


"A eukaryotic translation initiation factor 2 subunit 3 (human) that has had the initiator methionine removed. UniProtKB:P41091, 2-472." [PRO:DNx, Reactome:R-HSA-72514]


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CRHR2/iso:iv-beta forms found in complexes   

CRHR2/iso:iv-beta Component
Complexes
PR:Q9Z0N1 mEif2s3x PR:000026828 eukaryotic translation initiation factor 2 complex 1 (mouse)
PR:Q9Z0N2 mEif2s3y PR:000026829 eukaryotic translation initiation factor 2 complex 2 (mouse)