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Protein Ontology report - TAK1 kinase complex
PR:000027077 - http://purl.obolibrary.org/obo/PR_000027077
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027077   
  PRO nameTAK1 kinase complex 
  Synonyms
Other: RELATED:TAK1-TAB1-TAB2-TAB3
  Definition"A protein-containing complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunit)." [PMID:16410796, PMID:17496917, PMID:18021073, PRO:CNA] 
  CommentRequested GO term. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex2                                                  Organism-Complex 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000027077 TAK1 kinase complex
hGATA1/iso:1/PhosSumo:1

Yes
complex


PR:000027078 TRIKA2 complex
hGATA1/iso:1/PhosSumo:1

organism-complex


PR:000027105 TRIKA2 complex (mouse)
fam:hTAB2-hTAB3

organism-complex


PR:000027102 TAK1 kinase complex (mouse)
fam:mTAB2-mTAB3

organism-complex


PR:000035730 TAK1 kinase complex (human)
Ubiq
Yes
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hGATA1/iso:1/PhosSumo:1 forms found in complexes   

hGATA1/iso:1/PhosSumo:1 Component
 Complexes
PR:000027077 hGATA1/iso:1/PhosSumo:1 PR:000027079 TAK1 kinase-MKK6 complex
PR:000027080 TAK1 kinase-MKK6 complex 1
PR:000027081 TAK1 kinase-MKK6 complex 2
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035730 Ubiq acts_upstream_of_or_withinGO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_25222
GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
GO:0038095 Fc-epsilon receptor signaling pathway Reactome:REACT_163936