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Protein Ontology report - proto-oncogene tyrosine-protein kinase Src
PR:000027234 - http://purl.obolibrary.org/obo/PR_000027234
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000027234   
  PRO nameproto-oncogene tyrosine-protein kinase Src 
  Synonyms
PRO-Short-label: EXACT:SRC
Gene-based: RELATED:SRC1
Other: EXACT:p60-Src | pp60c-src | Proto-oncogene c-Src
  Definition"A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human SRC gene or a 1:1 ortholog thereof." [PMID:18789131, PRO:CNA] 
  PRO Categorygene 
  ParentPR:000002997 proto-oncogene SRC-like tyrosine-protein kinase
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence2                                                  Organism-Sequence 10                                        
         Modification1                                                  Organism-Modification 16                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2206
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
gene



PR:000027234

proto-oncogene tyrosine-protein kinase Src

SRC


"A proto-oncogene SRC-like tyrosine-protein kinase that is a translation product of the human SRC gene or a 1:1 ortholog thereof." [PMID:18789131, PRO:CNA]


organism-gene



PR:P00523

proto-oncogene tyrosine-protein kinase Src (chicken)

chick-SRC


"A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of chicken." [OMA:P00523, PRO:DNx]


organism-sequence



PR:P00523-1

proto-oncogene tyrosine-protein kinase Src isoform 1 (chicken)

chick-SRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00523-1." [PRO:DNx, UniProtKB:P00523]


organism-sequence



PR:P00523-2

proto-oncogene tyrosine-protein kinase Src isoform 2 (chicken)

chick-SRC/iso:2


"A proto-oncogene tyrosine-protein kinase Src (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P00523-2." [PRO:DNx, UniProtKB:P00523]


organism-gene



PR:P05480

proto-oncogene tyrosine-protein kinase Src (mouse)

mSRC


"A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of mouse." [OMA:P05480, PRO:DNx]


organism-sequence



PR:P05480-1

neuronal proto-oncogene tyrosine-protein kinase Src isoform 1 (mouse)

mSRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P05480-2

proto-oncogene tyrosine-protein kinase Src isoform m1 (mouse)

mSRC/iso:m1


"A proto-oncogene tyrosine-protein kinase Src (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05480-2." [PRO:DNx, UniProtKB:P05480]


organism-modification



PR:000037500

proto-oncogene tyrosine-protein kinase Src phosphorylated 1 (mouse)

mSRC/Phos:1


"A proto-oncogene tyrosine-protein kinase Src (mouse) that has been phosphorylated at the residue equivalent to Tyr-521 of the amino acid sequence represented by UniProtKB:P05480-2. UniProtKB:P05480, Tyr-521, MOD:00048." [PMID:23526378, PMID:2480346, PRO:HJD]


organism-modification



PR:000037501

proto-oncogene tyrosine-protein kinase Src phosphorylated 2 (mouse)

mSRC/Phos:2


"A proto-oncogene tyrosine-protein kinase Src (mouse) that has been phosphorylated at the residue equivalent to Tyr-418 of the amino acid sequence represented by UniProtKB:P05480-2. UniProtKB:P05480, Tyr-418, MOD:00048." [PMID:23526378, PMID:2480346, PRO:HJD]


organism-modification



PR:000037502

proto-oncogene tyrosine-protein kinase Src phosphorylated 3 (mouse)

mSRC/Phos:3


"A proto-oncogene tyrosine-protein kinase Src (mouse) that has been phosphorylated at the residues equivalent to Tyr-418 and Tyr-521 of the amino acid sequence represented by UniProtKB:P05480-2. UniProtKB:P05480, Tyr-418/Tyr-521, MOD:00048." [PMID:23526378, PMID:2480346, PRO:HJD]


organism-modification



PR:000049780

proto-oncogene tyrosine-protein kinase Src unphosphorylated 2 (mouse)

mSRC/UnPhos:2


"A proto-oncogene tyrosine-protein kinase Src (mouse) that lacks phosphorylation at the position equivalent to Tyr-418 of the amino acid sequence represented by UniProtKB:P05480-2. UniProtKB:P05480, Tyr-418, PR:000026291." [PMID:26764350, PRO:HJD]


organism-modification



PR:000049781

proto-oncogene tyrosine-protein kinase Src unphosphorylated 1 (mouse)

mSRC/UnPhos:1


"A proto-oncogene tyrosine-protein kinase Src (mouse) that lacks phosphorylation at the position equivalent to Tyr-521 of the amino acid sequence represented by UniProtKB:P05480-2. UniProtKB:P05480, Tyr-521, PR:000026291." [PMID:26764350, PRO:HJD]


organism-gene



PR:P12931

proto-oncogene tyrosine-protein kinase Src (human)

hSRC


"A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of human." [PRO:CNA, UniProtKB:P12931]


organism-sequence



PR:P12931-1

proto-oncogene tyrosine-protein kinase Src isoform 1 (human)

hSRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000063728

proto-oncogene tyrosine-protein kinase Src isoform 1, initiator methionine removed form (human)

hSRC/iso:1/InitMet-


"A proto-oncogene tyrosine-protein kinase Src isoform 1 (human) that has had the initiator methionine removed. UniProtKB:P12931-1, 2-536." [PRO:DNx, Reactome:R-HSA-354153, Reactome:R-HSA-65043]


organism-modification



PR:000027238

proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1 (human)

hSRC/iso:1/InitMet-/Phos:1


"A proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1 in human. UniProtKB:P12931-1, 2-536, Tyr-419, MOD:00048." [PMID:8789131, PRO:DAN, PRO:PD]


organism-sequence



PR:P12931-2

proto-oncogene tyrosine-protein kinase Src isoform 2 (human)

hSRC/iso:2


"A proto-oncogene tyrosine-protein kinase Src isoform 2 that is encoded in the genome of human." [PMID:1691439, PRO:CNA]


organism-sequence



PR:P12931-3

proto-oncogene tyrosine-protein kinase Src isoform h3 (human)

hSRC/iso:h3


"A proto-oncogene tyrosine-protein kinase Src (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12931-3." [PRO:DNx, UniProtKB:P12931]


organism-modification



PR:000045674

proto-oncogene tyrosine-protein kinase Src phosphorylated 1 (human)

hSRC/Phos:1


"A proto-oncogene tyrosine-protein kinase Src (human) that has been phosphorylated on the residue at the position equivalent to Ser-75 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, Ser-75, MOD:00046." [iPTMnet:P12931, PMID:10544291]


organism-modification



PR:000060310

proto-oncogene tyrosine-protein kinase Src, initiator methionine removed myristoylated and phosphorylated 1 (human)

hSRC/InitMet-/MyrPhos:1


"A proto-oncogene tyrosine-protein kinase Src (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 and phosphorylated on the residue at the position equivalent to Tyr-419 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, 2-536, Gly-2, MOD:00068|Tyr-419, MOD:00048." [PRO:DNx, Reactome:R-HSA-1810408]


organism-modification



PR:000061874

proto-oncogene tyrosine-protein kinase Src, initiator methionine removed phosphorylated 1 (human)

hSRC/InitMet-/Phos:1


"A proto-oncogene tyrosine-protein kinase Src (human) that has had the initiator methionine removed and that has been phosphorylated on the residue at the position equivalent to Tyr-419 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, 2-536, Tyr-419, MOD:00048." [PRO:DNx, Reactome:R-HSA-8937690]


organism-modification



PR:000063296

proto-oncogene tyrosine-protein kinase Src, initiator methionine removed myristoylated 1 (human)

hSRC/InitMet-/Myr:1


"A proto-oncogene tyrosine-protein kinase Src (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, 2-536, Gly-2, MOD:00068." [PRO:DNx, Reactome:R-HSA-8876922]


organism-modification



PR:000063550

proto-oncogene tyrosine-protein kinase Src, initiator methionine removed myristoylated and phosphorylated 2 (human)

hSRC/InitMet-/MyrPhos:2


"A proto-oncogene tyrosine-protein kinase Src (human) that has had the initiator methionine removed and that has been myristoylated on the residue at the position equivalent to Gly-2 and phosphorylated on the residue at the position equivalent to Tyr-530 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, 2-536, Gly-2, MOD:00068|Tyr-530, MOD:00048." [PRO:DNx, Reactome:R-HSA-377598]


organism-modification



PR:000068102

proto-oncogene tyrosine-protein kinase Src methylated 1 (human)

hSRC/Me:1


"A proto-oncogene tyrosine-protein kinase Src (human) that has been methylated on the residue at the position equivalent to Cys-403 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, Cys-403, MOD:00660." [IEDB_epitope:1021281, PRO:DNx]


organism-modification



PR:000074588

proto-oncogene tyrosine-protein kinase Src cysteinylated 1 (human)

hSRC/Cyst:1


"A proto-oncogene tyrosine-protein kinase Src (human) that has been cysteinylated on the residue at the position equivalent to Cys-403 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, Cys-403, MOD:00765." [IEDB_epitope:1307978, PRO:DNx]


organism-modification



PR:000079053

proto-oncogene tyrosine-protein kinase Src methylated 2 (human)

hSRC/Me:2


"A proto-oncogene tyrosine-protein kinase Src (human) that has been methylated on the residue at the position equivalent to Cys-241 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, Cys-241, MOD:00660." [IEDB_epitope:1017259, PRO:DNx]


organism-modification



PR:000080470

proto-oncogene tyrosine-protein kinase Src phosphorylated 2 (human)

hSRC/Phos:2


"A proto-oncogene tyrosine-protein kinase Src (human) that has been phosphorylated on the residue at the position equivalent to Ser-17 of the amino acid sequence represented by UniProtKB:P12931-1. Example: UniProtKB:P12931-1, Ser-17, MOD:00046." [IEDB_epitope:2148806, IEDB_epitope:2148810, PRO:DNx]


organism-gene



PR:Q1JPZ3

proto-oncogene tyrosine-protein kinase Src (zebrafish)

z-SRC


"A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of zebrafish." [OMA:Q1JPZ3, PRO:DNx]


organism-gene



PR:Q9WUD9

proto-oncogene tyrosine-protein kinase Src (rat)

rSRC


"A proto-oncogene tyrosine-protein kinase Src that is encoded in the genome of rat." [OMA:Q9WUD9, PRO:DNx]


organism-sequence



PR:Q9WUD9-1

proto-oncogene tyrosine-protein kinase Src isoform 1 (rat)

rSRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WUD9-1." [PRO:DNx, UniProtKB:Q9WUD9]


organism-sequence



PR:Q9WUD9-2

proto-oncogene tyrosine-protein kinase Src isoform r2 (rat)

rSRC/iso:r2


"A proto-oncogene tyrosine-protein kinase Src (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WUD9-2." [PRO:DNx, UniProtKB:Q9WUD9]


organism-sequence



PR:Q9WUD9-3

proto-oncogene tyrosine-protein kinase Src isoform r3 (rat)

rSRC/iso:r3


"A proto-oncogene tyrosine-protein kinase Src (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9WUD9-3." [PRO:DNx, UniProtKB:Q9WUD9]


sequence



PR:000027235

proto-oncogene tyrosine-protein kinase Src isoform 1

SRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12931-1 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P12931-1

proto-oncogene tyrosine-protein kinase Src isoform 1 (human)

hSRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src isoform 1 that is encoded in the genome of human." [PRO:CNA]


organism-modification



PR:000063728

proto-oncogene tyrosine-protein kinase Src isoform 1, initiator methionine removed form (human)

hSRC/iso:1/InitMet-


"A proto-oncogene tyrosine-protein kinase Src isoform 1 (human) that has had the initiator methionine removed. UniProtKB:P12931-1, 2-536." [PRO:DNx, Reactome:R-HSA-354153, Reactome:R-HSA-65043]


organism-modification



PR:000027238

proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1 (human)

hSRC/iso:1/InitMet-/Phos:1


"A proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1 in human. UniProtKB:P12931-1, 2-536, Tyr-419, MOD:00048." [PMID:8789131, PRO:DAN, PRO:PD]


modification



PR:000027237

proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1

SRC/iso:1/InitMet-/Phos:1


"A proto-oncogene tyrosine-protein kinase Src isoform 1 that has had the initiator methionine removed and that has been post-translationally modified to include a phosphotyrosine following irradiation. Example: UniProtKB:P12931-1, Tyr-419, MOD:00048." [PRO:CNA]


organism-modification



PR:000027238

proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1 (human)

hSRC/iso:1/InitMet-/Phos:1


"A proto-oncogene tyrosine-protein kinase Src isoform 1 initiator methionine removed phosphorylated 1 in human. UniProtKB:P12931-1, 2-536, Tyr-419, MOD:00048." [PMID:8789131, PRO:DAN, PRO:PD]


sequence



PR:000027239

proto-oncogene tyrosine-protein kinase Src isoform 2

SRC/iso:2


"A proto-oncogene tyrosine-protein kinase Src that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12931-2 or a 1:1 ortholog thereof." [PRO:CNA]


organism-sequence



PR:P05480-1

neuronal proto-oncogene tyrosine-protein kinase Src isoform 1 (mouse)

mSRC/iso:1


"A proto-oncogene tyrosine-protein kinase Src isoform 2 that is encoded in the genome of mouse." [PRO:CNA]


organism-sequence



PR:P12931-2

proto-oncogene tyrosine-protein kinase Src isoform 2 (human)

hSRC/iso:2


"A proto-oncogene tyrosine-protein kinase Src isoform 2 that is encoded in the genome of human." [PMID:1691439, PRO:CNA]