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Protein Ontology report - nuclear receptor coactivator 3 isoform 1
PR:000027689 - http://purl.obolibrary.org/obo/PR_000027689
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027689   
  PRO namenuclear receptor coactivator 3 isoform 1 
  Synonyms
PRO-Short-label: EXACT:NCOA3/iso:1
  Definition"A nuclear receptor coactivator 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Q9-1 or a 1:1 ortholog thereof." [PMID:18922467, PMID:21577200, PRO:PD] 
  PRO Categorysequence 
  ParentPR:000011042 nuclear receptor coactivator 3
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification6                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000027689
nuclear receptor coactivator 3 isoform 1
NCOA3/iso:1
"A nuclear receptor coactivator 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9Y6Q9-1 or a 1:1 ortholog thereof." [PMID:18922467, PMID:21577200, PRO:PD]

organism-sequence


PR:Q9Y6Q9-1
nuclear receptor coactivator 3 isoform 1 (human)
hNCOA3/iso:1
"A nuclear receptor coactivator 3 isoform 1 that is encoded in the genome of human." [PRO:PD]

organism-modification


PR:000027692
nuclear receptor coactivator 3 isoform 1 phosphorylated 1 (human)
hNCOA3/iso:1/Phos:1
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046." [PMID:18922467, PMID:21577200, PRO:PD]
Yes
organism-modification


PR:000027694
nuclear receptor coactivator 3 isoform 1 phosphorylated 2 (human)
hNCOA3/iso:1/Phos:2
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 2 in human. UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046." [PMID:19339517, PRO:PD]
Yes
organism-modification


PR:000027696
nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human)
hNCOA3/iso:1/Phos:3
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 3 in human. UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048." [PMID:18765637, PRO:PD]
Yes
organism-modification


PR:000027698
nuclear receptor coactivator 3 isoform 1 phosphorylated 4 (human)
hNCOA3/iso:1/Phos:4
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 4 in human. UniProtKB:Q9Y6Q9-1, Ser-857, MOD:00046." [PMID:15383283, PRO:PD]

organism-modification


PR:000027885
nuclear receptor coactivator 3 isoform 1 acetylated 1 (human)
hNCOA3/iso:1/Ac:1
"A nuclear receptor coactivator 3 isoform 1 acetylated 1 in human. UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064." [PMID:10490106, PRO:PD]
Yes
organism-modification


PR:000027887
nuclear receptor coactivator 3 isoform 1 acetylated 2 (human)
hNCOA3/iso:1/Ac:2
"A nuclear receptor coactivator 3 isoform 1 acetylated 2 in human. UniProtKB:Q9Y6Q9-1, Lys-687, MOD:00064." [PMID:19608861, PRO:PD]

modification


PR:000027691
nuclear receptor coactivator 3 isoform 1 phosphorylated 1
NCOA3/iso:1/Phos:1
"A nuclear receptor coactivator 3 isoform 1 that has been phosphorylated on Ser residues by Casein kinase I. Example: UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046." [PMID:18922467, PMID:21577200, PRO:PD]

organism-modification


PR:000027692
nuclear receptor coactivator 3 isoform 1 phosphorylated 1 (human)
hNCOA3/iso:1/Phos:1
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 1 in human. UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046." [PMID:18922467, PMID:21577200, PRO:PD]
Yes
modification


PR:000027693
nuclear receptor coactivator 3 isoform 1 phosphorylated 2
NCOA3/iso:1/Phos:2
"A nuclear receptor coactivator 3 isoform 1 that has been phosphorylated on a Ser residue within the RID domain. Example: UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046." [PMID:19339517, PRO:PD]

organism-modification


PR:000027694
nuclear receptor coactivator 3 isoform 1 phosphorylated 2 (human)
hNCOA3/iso:1/Phos:2
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 2 in human. UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046." [PMID:19339517, PRO:PD]
Yes
modification


PR:000027695
nuclear receptor coactivator 3 isoform 1 phosphorylated 3
NCOA3/iso:1/Phos:3
"A nuclear receptor coactivator 3 isoform 1 that has been phosphorylated on a C-terminal Tyr residue after the Gln rich region. Example: UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048." [PMID:18765637, PRO:PD]

organism-modification


PR:000027696
nuclear receptor coactivator 3 isoform 1 phosphorylated 3 (human)
hNCOA3/iso:1/Phos:3
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 3 in human. UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048." [PMID:18765637, PRO:PD]
Yes
modification


PR:000027697
nuclear receptor coactivator 3 isoform 1 phosphorylated 4
NCOA3/iso:1/Phos:4
"A nuclear receptor coactivator 3 isoform 1 that has been phosphorylated on the residue at the position equivalent to Ser-857 of the amino acid sequence represented by UniProtKB:Q9Y6Q9-1. Example: UniProtKB:Q9Y6Q9-1, Ser-857, MOD:00046." [PMID:15383283, PRO:PD]

organism-modification


PR:000027698
nuclear receptor coactivator 3 isoform 1 phosphorylated 4 (human)
hNCOA3/iso:1/Phos:4
"A nuclear receptor coactivator 3 isoform 1 phosphorylated 4 in human. UniProtKB:Q9Y6Q9-1, Ser-857, MOD:00046." [PMID:15383283, PRO:PD]

modification


PR:000027884
nuclear receptor coactivator 3 isoform 1 acetylated 1
NCOA3/iso:1/Ac:1
"A nuclear receptor coactivator 3 isoform 1 that is acetylated on the Lys residues at -1 and -2 positions of the first LxxLL motif (conserved sequence KKLLQLL). Example: UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064." [PMID:10490106, PRO:PD]

organism-modification


PR:000027885
nuclear receptor coactivator 3 isoform 1 acetylated 1 (human)
hNCOA3/iso:1/Ac:1
"A nuclear receptor coactivator 3 isoform 1 acetylated 1 in human. UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064." [PMID:10490106, PRO:PD]
Yes
modification


PR:000027886
nuclear receptor coactivator 3 isoform 1 acetylated 2
NCOA3/iso:1/Ac:2
"A nuclear receptor coactivator 3 isoform 1 that is acetylated on the Lys residue within the second LxxLL motif (conserved sequence LHKLL). Example: UniProtKB:Q9Y6Q9-1, Lys-687, MOD:00064." [PMID:19608861, PRO:PD]

organism-modification


PR:000027887
nuclear receptor coactivator 3 isoform 1 acetylated 2 (human)
hNCOA3/iso:1/Ac:2
"A nuclear receptor coactivator 3 isoform 1 acetylated 2 in human. UniProtKB:Q9Y6Q9-1, Lys-687, MOD:00064." [PMID:19608861, PRO:PD]

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027692 hNCOA3/iso:1/Phos:1
UniProtKB:Q9Y6Q9-1, Ser-101/Ser-102, MOD:00046		 enablesGO:0005515 protein binding with PR:O43791 HIB homolog 1 (human) PMID:21577200
PR:000027694 hNCOA3/iso:1/Phos:2
UniProtKB:Q9Y6Q9-1, Ser-601, MOD:00046		 acts_upstream_of_or_withinGO:0003713 transcription coactivator activity PMID:19339517
enablesGO:0003713 transcription coactivator activity PMID:19339517
PR:000027696 hNCOA3/iso:1/Phos:3
UniProtKB:Q9Y6Q9-1, Tyr-1357, MOD:00048		 acts_upstream_of_or_withinGO:0003713 transcription coactivator activity PMID:18765637
enablesGO:0030331 nuclear estrogen receptor binding with PR:000007204 ER PMID:18765637
GO:0035035 histone acetyltransferase binding PMID:18765637
PR:000027885 hNCOA3/iso:1/Ac:1
UniProtKB:Q9Y6Q9-1, Lys-619/Lys-620, MOD:00064		 enablesNOT GO:0016922 nuclear receptor binding PMID:10490106