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Protein Ontology report - traf3:ticam1:ticam2:activated TLR4 complex
PR:000028681 - http://purl.obolibrary.org/obo/PR_000028681
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000028681   
  PRO nametraf3:ticam1:ticam2:activated TLR4 complex 
  Synonyms
Other: EXACT:TRAF3:TRIF:TRAM:activated TLR4
  Definition"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1 and TRAF3." [PMID:16306937, Reactome:R-HSA-2201339] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000028681
traf3:ticam1:ticam2:activated TLR4 complex
TICAM1/PhosRes+
"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1 and TRAF3." [PMID:16306937, Reactome:R-HSA-2201339]

organism-complex


PR:000028683
traf3:ticam1:ticam2:activated TLR4 complex (mouse)
TICAM1/PhosRes+
"A traf3:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of mouse." [PMID:16306937]
Yes
organism-complex


PR:000036022
traf3:ticam1:ticam2:activated TLR4 complex (human)
BTBD7/iso:3
"A traf3:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [PMID:16306936, PMID:16306937, Reactome:R-HSA-2201339]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000028683 TICAM1/PhosRes+ acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:16306937
GO:0034142 toll-like receptor 4 signaling pathway PMID:16306937
PR:000036022 BTBD7/iso:3 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_124037
enablesGO:0004842 ubiquitin-protein transferase activity Reactome:REACT_124037
located_inGO:0010008 endosome membrane Reactome:REACT_124037