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Protein Ontology report - pUbtraf6:ticam1:ticam2:activated TLR4 complex
PR:000028705 - http://purl.obolibrary.org/obo/PR_000028705
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000028705   
  PRO namepUbtraf6:ticam1:ticam2:activated TLR4 complex 
  Synonyms
Other: RELATED:activated TLR4:TRAM:TRIF:K63-pUb-TRAF6
  Definition"A traf6:ticam1:ticam2:activated TLR4 complex in which TRAF6 is polyubiquitinated. Ubiquitin is attached to TRAF6 through an isopeptide bond between the C-terminus of ubiquitin and the epsilon-amino group of a Lys residue in the target protein." [Reactome:R-HSA-936965] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentPR:000028679 traf6:ticam1:ticam2:activated TLR4 complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000028705
pUbtraf6:ticam1:ticam2:activated TLR4 complex
hIRF7/UnMod
"A traf6:ticam1:ticam2:activated TLR4 complex in which TRAF6 is polyubiquitinated. Ubiquitin is attached to TRAF6 through an isopeptide bond between the C-terminus of ubiquitin and the epsilon-amino group of a Lys residue in the target protein." [Reactome:R-HSA-936965]

organism-complex


PR:000035715
pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
hTRAF6/K63polyUbiq:1
"A pUbtraf6:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [PRO:DAN, Reactome:R-HSA-936965]
Yes
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0002756 MyD88-independent toll-like receptor signaling pathwayPR:000035715 hTRAF6/K63polyUbiq:1 Reactome:REACT_6809

Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0010008 endosome membranePR:000035715 hTRAF6/K63polyUbiq:1 Reactome:REACT_25867