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Protein Ontology report - phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1
PR:000028747 -
http://purl.obolibrary.org/obo/PR_000028747
Protein Forms
Ontology Information
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PRO ID
PR:000028747
PRO name
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1
Synonyms
PRO-Short-label
:
EXACT:
PTEN/iso:1
Definition
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:P60484-1
or a 1:1 ortholog thereof." [
PMID:18757404
, PRO:PD]
PRO Category
sequence
Parent
PR:000028746
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
2
Organism-Modification
2
Term Hierarchy
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OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000028747
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1
PTEN/iso:1
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P60484-1 or a 1:1 ortholog thereof." [PMID:18757404, PRO:PD]
organism-sequence
PR:P60484-1
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 (human)
hPTEN/iso:1
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 that is encoded in the genome of human." [PRO:PD]
organism-modification
PR:000028750
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1 (human)
hPTEN/iso:1/Ac:1
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1 in human. Acetylation within the PDZ domain alters PTEN interaction with PDZ domain-containing proteins, and thus may modulate PTEN function. UniProtKB:P60484-1, Lys-402, MOD:00064." [PMID:18757404, PRO:PD]
organism-modification
PR:000028805
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 (human)
hPTEN/iso:1/Ac:2
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 in human. UniProtKB:P60484-1, Lys-125/Lys-128, MOD:00064." [PMID:16829519, PRO:PD]
modification
PR:000028749
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1
PTEN/iso:1/Ac:1
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 that has been acetylated on a Lys residue located within the PDZ domain-binding motif at the C-terminus. Example: UniProtKB:P60484-1, Lys-402, MOD:00064." [PMID:18757404, PRO:PD]
organism-modification
PR:000028750
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1 (human)
hPTEN/iso:1/Ac:1
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 1 in human. Acetylation within the PDZ domain alters PTEN interaction with PDZ domain-containing proteins, and thus may modulate PTEN function. UniProtKB:P60484-1, Lys-402, MOD:00064." [PMID:18757404, PRO:PD]
modification
PR:000028804
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2
PTEN/iso:1/Ac:2
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 that has been acetylated on Lys residues located within the catalytic core domain. Example: UniProtKB:P60484-1, Lys-125/Lys-128, MOD:00064." [PMID:10619020, PRO:PD]
organism-modification
PR:000028805
phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 (human)
hPTEN/iso:1/Ac:2
"A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform 1 acetylated 2 in human. UniProtKB:P60484-1, Lys-125/Lys-128, MOD:00064." [PMID:16829519, PRO:PD]
