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Protein Ontology report - creatine kinase
PR:000029971 - http://purl.obolibrary.org/obo/PR_000029971
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000029971   
  PRO namecreatine kinase 
  Synonyms
PRO-Short-label: EXACT:fam:CK
  Definition"A protein that contains a single ATP:guanido phosphotransferase N-terminal domain (Pfam:PF02807) followed by a single ATP:guanido phosphotransferase C-terminal catalytic domain (Pfam:PF00217)." [PRO:DAN] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 1                                        
         Gene4                                                  Organism-Gene 14                                        
         Sequence3                                                  Organism-Sequence 13                                        
         Modification5                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000029971

creatine kinase

fam:CK


"A protein that contains a single ATP:guanido phosphotransferase N-terminal domain (Pfam:PF02807) followed by a single ATP:guanido phosphotransferase C-terminal catalytic domain (Pfam:PF00217)." [PRO:DAN]


gene



PR:000005513

creatine kinase B-type

CKB


"A creatine kinase that is a translation product of the human CKB gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P05122

creatine kinase B-type (chicken)

chick-CKB


"A creatine kinase B-type that is encoded in the genome of chicken." [OMA:P05122, PRO:DNx]


organism-sequence



PR:P05122-1

creatine kinase B-type isoform Bb-CK-1 (chicken)

chick-CKB/iso:Bb-CK-1


"A creatine kinase B-type (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05122-1." [PRO:DNx, UniProtKB:P05122]


organism-sequence



PR:P05122-2

creatine kinase B-type isoform Ba-CK (chicken)

chick-CKB/iso:Ba-CK


"A creatine kinase B-type (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05122-2." [PRO:DNx, UniProtKB:P05122]


organism-sequence



PR:P05122-3

creatine kinase B-type isoform Bb-CK-2 (chicken)

chick-CKB/iso:Bb-CK-2


"A creatine kinase B-type (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05122-3." [PRO:DNx, UniProtKB:P05122]


organism-sequence



PR:P05122-4

creatine kinase B-type isoform Bb-CK-3 (chicken)

chick-CKB/iso:Bb-CK-3


"A creatine kinase B-type (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05122-4." [PRO:DNx, UniProtKB:P05122]


organism-sequence



PR:P05122-5

creatine kinase B-type isoform Bb-CK-4 (chicken)

chick-CKB/iso:Bb-CK-4


"A creatine kinase B-type (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P05122-5." [PRO:DNx, UniProtKB:P05122]


organism-gene



PR:P07335

creatine kinase B-type (rat)

rCKB


"A creatine kinase B-type that is encoded in the genome of rat." [OMA:P07335, PRO:DNx]


organism-gene



PR:P12277

creatine kinase B-type (human)

hCKB


"A creatine kinase B-type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12277]


organism-sequence



PR:P12277-1

creatine kinase B-type isoform 1 (human)

hCKB/iso:1


"A creatine kinase B-type isoform 1 that is encoded in the genome of human." [PRO:HJD]


Yes
organism-modification



PR:000046727

creatine kinase B-type, initiator methionine removed form (human)

hCKB/InitMet-


"A creatine kinase B-type (human) that has had the initiator methionine removed. UniProtKB:P12277, 2-381." [PRO:DNx, Reactome:R-HSA-200355]


organism-gene



PR:Q04447

creatine kinase B-type (mouse)

mCKB


"A creatine kinase B-type that is encoded in the genome of mouse." [OMA:Q04447, PRO:DNx]


organism-sequence



PR:Q04447-1

creatine kinase B-type isoform 1 (mouse)

mCKB/iso:1


"A creatine kinase B-type isoform 1 that is encoded in the genome of mouse." [PMID:1740343, PRO:HJD]


Yes
organism-modification



PR:000027162

creatine kinase B-type isoform 1 nitrated 1 (mouse)

mCKB/iso:1/Nitro:1


"A creatine kinase B-type isoform 1 nitrated 1 in mouse. UniProtKB:Q04447-1, Tyr-269, MOD:01786." [PMID:16800626, PRO:HJD]


organism-modification



PR:000027164

creatine kinase B-type isoform 1 phosphorylated 1 (mouse)

mCKB/iso:1/Phos:1


"A creatine kinase B-type isoform 1 phosphorylated 1 in mouse. UniProtKB:Q04447-1, Ser-164, MOD:00046." [PMID:15648052, PRO:HJD]


sequence



PR:000027159

creatine kinase B-type isoform 1

CKB/iso:1


"A creatine kinase B-type that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04447-1 or a 1:1 ortholog thereof." [PMID:1740343, PRO:HJD]


Yes
organism-sequence



PR:P12277-1

creatine kinase B-type isoform 1 (human)

hCKB/iso:1


"A creatine kinase B-type isoform 1 that is encoded in the genome of human." [PRO:HJD]


Yes
organism-sequence



PR:Q04447-1

creatine kinase B-type isoform 1 (mouse)

mCKB/iso:1


"A creatine kinase B-type isoform 1 that is encoded in the genome of mouse." [PMID:1740343, PRO:HJD]


Yes
organism-modification



PR:000027162

creatine kinase B-type isoform 1 nitrated 1 (mouse)

mCKB/iso:1/Nitro:1


"A creatine kinase B-type isoform 1 nitrated 1 in mouse. UniProtKB:Q04447-1, Tyr-269, MOD:01786." [PMID:16800626, PRO:HJD]


organism-modification



PR:000027164

creatine kinase B-type isoform 1 phosphorylated 1 (mouse)

mCKB/iso:1/Phos:1


"A creatine kinase B-type isoform 1 phosphorylated 1 in mouse. UniProtKB:Q04447-1, Ser-164, MOD:00046." [PMID:15648052, PRO:HJD]


modification



PR:000027161

creatine kinase B-type isoform 1 nitrated 1

CKB/iso:1/Nitro:1


"A creatine kinase B-type isoform 1 that has been nitrated at a residue equivalent to Tyr-269 of the amino acid sequence represented by UniProtKB:Q04447-1. Example: UniProtKB:Q04447-1, Tyr-269, MOD:01786." [PMID:16800626, PRO:DAN, PRO:HJD]


organism-modification



PR:000027162

creatine kinase B-type isoform 1 nitrated 1 (mouse)

mCKB/iso:1/Nitro:1


"A creatine kinase B-type isoform 1 nitrated 1 in mouse. UniProtKB:Q04447-1, Tyr-269, MOD:01786." [PMID:16800626, PRO:HJD]


modification



PR:000027163

creatine kinase B-type isoform 1 phosphorylated 1

CKB/iso:1/Phos:1


"A creatine kinase B-type isoform 1 that has been post-translationally modified to include a phosphoserine residue. Example: UniProtKB:Q04447-1, Ser-164, MOD:00046." [PRO:CNA]


organism-modification



PR:000027164

creatine kinase B-type isoform 1 phosphorylated 1 (mouse)

mCKB/iso:1/Phos:1


"A creatine kinase B-type isoform 1 phosphorylated 1 in mouse. UniProtKB:Q04447-1, Ser-164, MOD:00046." [PMID:15648052, PRO:HJD]


modification



PR:000019356

creatine kinase B-type, initiator methionine removed form

CKB/InitMet-


"A creatine kinase B-type that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000046727

creatine kinase B-type, initiator methionine removed form (human)

hCKB/InitMet-


"A creatine kinase B-type (human) that has had the initiator methionine removed. UniProtKB:P12277, 2-381." [PRO:DNx, Reactome:R-HSA-200355]


gene



PR:000005515

creatine kinase M-type

CKM


"A creatine kinase that is a translation product of the human CKM gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P00563

creatine kinase M-type (rabbit)

rabbit-CKM


"A creatine kinase M-type that is encoded in the genome of rabbit." [OMA:P00563, PRO:DNx]


organism-gene



PR:P06732

creatine kinase M-type (human)

hCKM


"A creatine kinase M-type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P06732]


organism-sequence



PR:P06732-1

creatine kinase M-type isoform 1 (human)

hCKM/iso:1


"A creatine kinase M-type isoform 1 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-gene



PR:P07310

creatine kinase M-type (mouse)

mCKM


"A creatine kinase M-type that is encoded in the genome of mouse." [OMA:P07310, PRO:DNx]


organism-sequence



PR:P07310-1

creatine kinase M-type isoform 1 (mouse)

mCKM/iso:1


"A creatine kinase M-type isoform 1 that is encoded in the genome of mouse." [PMID:3003372, PRO:HJD]


Yes
sequence



PR:000027157

creatine kinase M-type isoform 1

CKM/iso:1


"A creatine kinase M-type that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P07310-1 or a 1:1 ortholog thereof." [PRO:CNA]


Yes
organism-sequence



PR:P06732-1

creatine kinase M-type isoform 1 (human)

hCKM/iso:1


"A creatine kinase M-type isoform 1 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-sequence



PR:P07310-1

creatine kinase M-type isoform 1 (mouse)

mCKM/iso:1


"A creatine kinase M-type isoform 1 that is encoded in the genome of mouse." [PMID:3003372, PRO:HJD]


Yes
gene



PR:000005516

creatine kinase U-type, mitochondrial

CKMT1


"A creatine kinase that is a translation product of the human CKMT1A or CKMT1B genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]


organism-gene



PR:P12532

creatine kinase U-type, mitochondrial (human)

hCKMT1


"A creatine kinase U-type, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12532]


organism-sequence



PR:P12532-1

creatine kinase U-type, mitochondrial isoform 1 (human)

hCKMT1/iso:1


"A creatine kinase U-type, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12532-1." [PRO:DNx, UniProtKB:P12532]


organism-sequence



PR:P12532-2

creatine kinase U-type, mitochondrial isoform 2 (human)

hCKMT1/iso:2


"A creatine kinase U-type, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12532-2." [PRO:DNx, UniProtKB:P12532]


organism-modification



PR:000050104

creatine kinase U-type, mitochondrial, transit peptide removed form (human)

hCKMT1/TransPep-


"A creatine kinase U-type, mitochondrial, transit peptide removed form in human. UniProtKB:P12532, 40-417." [PRO:DAN]


Yes
organism-gene



PR:P25809

creatine kinase U-type, mitochondrial (rat)

rCKMT1


"A creatine kinase U-type, mitochondrial that is encoded in the genome of rat." [OMA:P25809, PRO:DNx]


organism-gene



PR:P30275

creatine kinase U-type, mitochondrial (mouse)

mCKMT1


"A creatine kinase U-type, mitochondrial that is encoded in the genome of mouse." [OMA:P30275, PRO:DNx]


modification



PR:000019358

creatine kinase U-type, mitochondrial, transit peptide removed form

CKMT1/TransPep-


"A creatine kinase U-type, mitochondrial that has had the transit peptide removed." [PRO:DNx]


Yes
organism-modification



PR:000050104

creatine kinase U-type, mitochondrial, transit peptide removed form (human)

hCKMT1/TransPep-


"A creatine kinase U-type, mitochondrial, transit peptide removed form in human. UniProtKB:P12532, 40-417." [PRO:DAN]


Yes
gene



PR:000005517

creatine kinase S-type, mitochondrial

CKMT2


"A creatine kinase that is a translation product of the human CKMT2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P09605

creatine kinase S-type, mitochondrial (rat)

rCKMT2


"A creatine kinase S-type, mitochondrial that is encoded in the genome of rat." [OMA:P09605, PRO:DNx]


organism-gene



PR:P11009

creatine kinase S-type, mitochondrial (chicken)

chick-CKMT2


"A creatine kinase S-type, mitochondrial that is encoded in the genome of chicken." [OMA:P11009, PRO:DNx]


organism-gene



PR:P17540

creatine kinase S-type, mitochondrial (human)

hCKMT2


"A creatine kinase S-type, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17540]


organism-sequence



PR:P17540-1

creatine kinase S-type, mitochondrial isoform 1 (human)

hCKMT2/iso:1


"A creatine kinase S-type, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000046728

creatine kinase S-type, mitochondrial, transit peptide removed form (human)

hCKMT2/TransPep-


"A creatine kinase S-type, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P17540, 40-419." [PRO:DNx, Reactome:R-HSA-200325]


Yes
organism-gene



PR:Q6P8J7

creatine kinase S-type, mitochondrial (mouse)

mCKMT2


"A creatine kinase S-type, mitochondrial that is encoded in the genome of mouse." [OMA:Q6P8J7, PRO:DNx]


organism-sequence



PR:Q6P8J7-1

creatine kinase S-type, mitochondrial isoform 1 (mouse)

mCKMT2/iso:1


"A creatine kinase S-type, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


sequence



PR:000038980

creatine kinase S-type, mitochondrial isoform 1

CKMT2/iso:1


"A creatine kinase S-type, mitochondrial that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P17540-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P17540-1

creatine kinase S-type, mitochondrial isoform 1 (human)

hCKMT2/iso:1


"A creatine kinase S-type, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-sequence



PR:Q6P8J7-1

creatine kinase S-type, mitochondrial isoform 1 (mouse)

mCKMT2/iso:1


"A creatine kinase S-type, mitochondrial isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


modification



PR:000019360

creatine kinase S-type, mitochondrial, transit peptide removed form

CKMT2/TransPep-


"A creatine kinase S-type, mitochondrial that has had the transit peptide removed." [PRO:DNx]


Yes
organism-modification



PR:000046728

creatine kinase S-type, mitochondrial, transit peptide removed form (human)

hCKMT2/TransPep-


"A creatine kinase S-type, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P17540, 40-419." [PRO:DNx, Reactome:R-HSA-200325]


Yes
organism-family



PR:000050097

creatine kinase (human)

fam:hCK


"A creatine kinase that is encoded in the genome of human." [PRO:DAN]


Yes
organism-gene



PR:P06732

creatine kinase M-type (human)

hCKM


"A creatine kinase M-type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P06732]


organism-sequence



PR:P06732-1

creatine kinase M-type isoform 1 (human)

hCKM/iso:1


"A creatine kinase M-type isoform 1 that is encoded in the genome of human." [PRO:CNA]


Yes
organism-gene



PR:P12277

creatine kinase B-type (human)

hCKB


"A creatine kinase B-type that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12277]


organism-sequence



PR:P12277-1

creatine kinase B-type isoform 1 (human)

hCKB/iso:1


"A creatine kinase B-type isoform 1 that is encoded in the genome of human." [PRO:HJD]


Yes
organism-modification



PR:000046727

creatine kinase B-type, initiator methionine removed form (human)

hCKB/InitMet-


"A creatine kinase B-type (human) that has had the initiator methionine removed. UniProtKB:P12277, 2-381." [PRO:DNx, Reactome:R-HSA-200355]


organism-gene



PR:P12532

creatine kinase U-type, mitochondrial (human)

hCKMT1


"A creatine kinase U-type, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P12532]


organism-sequence



PR:P12532-1

creatine kinase U-type, mitochondrial isoform 1 (human)

hCKMT1/iso:1


"A creatine kinase U-type, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12532-1." [PRO:DNx, UniProtKB:P12532]


organism-sequence



PR:P12532-2

creatine kinase U-type, mitochondrial isoform 2 (human)

hCKMT1/iso:2


"A creatine kinase U-type, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P12532-2." [PRO:DNx, UniProtKB:P12532]


organism-modification



PR:000050104

creatine kinase U-type, mitochondrial, transit peptide removed form (human)

hCKMT1/TransPep-


"A creatine kinase U-type, mitochondrial, transit peptide removed form in human. UniProtKB:P12532, 40-417." [PRO:DAN]


Yes
organism-gene



PR:P17540

creatine kinase S-type, mitochondrial (human)

hCKMT2


"A creatine kinase S-type, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:P17540]


organism-sequence



PR:P17540-1

creatine kinase S-type, mitochondrial isoform 1 (human)

hCKMT2/iso:1


"A creatine kinase S-type, mitochondrial isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000046728

creatine kinase S-type, mitochondrial, transit peptide removed form (human)

hCKMT2/TransPep-


"A creatine kinase S-type, mitochondrial (human) that has had the transit peptide removed. UniProtKB:P17540, 40-419." [PRO:DNx, Reactome:R-HSA-200325]


Yes
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fam:CK forms found in complexes   

fam:CK Component
Complexes
PR:000019358 CKMT1/TransPep- PR:000050030 mitochondrial creatine kinase complex, U-type
PR:000019360 CKMT2/TransPep- PR:000050031 mitochondrial creatine kinase complex, S-type
PR:000027157 CKM/iso:1 PR:000027245 cytosolic creatine kinase complex, M-type
PR:000027247 cytosolic creatine kinase complex, MB-type
PR:000027159 CKB/iso:1 PR:000027243 cytosolic creatine kinase complex, B-type
PR:000027247 cytosolic creatine kinase complex, MB-type
PR:000046728 hCKMT2/TransPep- PR:000050358 mitochondrial creatine kinase complex, S-type (human)
PR:000050097 fam:hCK PR:000050361 creatine kinase complex (human)
PR:000050104 hCKMT1/TransPep- PR:000050357 mitochondrial creatine kinase complex, U-type (human)
PR:P06732ZDASHZ1 hCKM/iso:1 PR:000050355 cytosolic creatine kinase complex, M-type (human)
PR:000050356 cytosolic creatine kinase complex, MB-type (human)
PR:P07310ZDASHZ1 mCKM/iso:1 PR:000027246 cytosolic creatine kinase complex, M-type (mouse)
PR:000027248 cytosolic creatine kinase complex, MB-type (mouse)
PR:P12277ZDASHZ1 hCKB/iso:1 PR:000050354 cytosolic creatine kinase complex, B-type (human)
PR:000050356 cytosolic creatine kinase complex, MB-type (human)
PR:Q04447ZDASHZ1 mCKB/iso:1 PR:000027244 cytosolic creatine kinase complex, B-type (mouse)
PR:000027248 cytosolic creatine kinase complex, MB-type (mouse)