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Protein Ontology report - PRNP gene translation product (human)
PR:000030020 - http://purl.obolibrary.org/obo/PR_000030020
 
  Protein Forms      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000030020   
  PRO namePRNP gene translation product (human) 
  Synonyms
PRO-Short-label: EXACT:hPRNP
Other: NARROW:ALTPRP (human) | AltPrP (human)
  Definition"A major prion protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:F7VJQ1
  PRO Categoryorganism-gene 
  ParentPR:000001886 major prion protein
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:9449 PRNP (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:000030020

PRNP gene translation product (human)

hPRNP


"A major prion protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:F7VJQ1]


organism-sequence



PR:F7VJQ1-1

alternative prion protein (human)

hPRNP/iso:AltPrP


"A PRNP gene translation product (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F7VJQ1-1." [PRO:DNx, UniProtKB:F7VJQ1]


organism-seqgroup



PR:P04156

major prion protein (human)

hPRNP/iso:major


"A PRNP gene translation product (human) that is encoded by the major prion protein open reading frame, as opposed to the alternate reading frame." [PRO:DAN]


organism-sequence



PR:P04156-1

major prion protein isoform 1 (human)

hPRNP/iso:1


"A major prion protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04156-1." [PRO:DNx, UniProtKB:P04156]


organism-modification



PR:000053314

major prion protein N-glycosylated 1 (human)

hPRNP/NGlyco:1


"A major prion protein (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P04156-1, in which the glycan composition is represented by GlyTouCan:G25987BV. Example: UniProtKB:P04156-1, Asn-197, MOD:00160~GNO:G25987BV." [GlyGen:P04156-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000053315

major prion protein N-glycosylated 2 (human)

hPRNP/NGlyco:2


"A major prion protein (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P04156-1, in which the glycan composition is represented by GlyTouCan:G59937CP. Example: UniProtKB:P04156-1, Asn-197, MOD:00160~GNO:G59937CP." [GlyGen:P04156-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000053316

major prion protein N-glycosylated 3 (human)

hPRNP/NGlyco:3


"A major prion protein (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P04156-1, in which the glycan composition is represented by GlyTouCan:G88725PI. Example: UniProtKB:P04156-1, Asn-197, MOD:00160~GNO:G88725PI." [GlyGen:P04156-1, PMID:29671580, PRO:DNx]


organism-modification



PR:000069910

major prion protein, mature form (human)

hPRNP/iso:major/mature


"A major prion protein (human) that has had the signal peptide and propeptide removed. Example: UniProtKB:P04156-1, 23-230." [PRO:DNx, Reactome:R-HSA-375060, Reactome:R-HSA-9617597]


organism-modification



PR:000077836

major prion protein deaminated 1 (human)

hPRNP/iso:major/Deam:1


"A major prion protein (human) that has been deaminated on the residue at the position equivalent to Asn-108 of the amino acid sequence represented by UniProtKB:P04156-1. Example: UniProtKB:P04156-1, Asn-108, MOD:00684." [IEDB_epitope:995223, PRO:DNx]