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Protein Ontology report - spindle assembly checkpoint component MAD3 phosphorylated 2
PR:000035502 - http://purl.obolibrary.org/obo/PR_000035502
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035502   
  PRO namespindle assembly checkpoint component MAD3 phosphorylated 2 
  Synonyms
PRO-Short-label: EXACT:MAD3/Phos:2
  Definition"A spindle assembly checkpoint component MAD3 that has been phosphorylated during spindle checkpoint activation on residues equivalent to Ser-303 and Ser-337 of the amino acid sequence represented by UniProtKB:P47074. Example: UniProtKB:P47074, Ser-303/Ser-337, MOD:00046." [PMID:17504936, PRO:KER] 
  PRO Categorymodification 
  ParentPR:000035499 spindle assembly checkpoint component MAD3
PR:000037070 phosphoprotein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000035502
spindle assembly checkpoint component MAD3 phosphorylated 2
MAD3/Phos:2
"A spindle assembly checkpoint component MAD3 that has been phosphorylated during spindle checkpoint activation on residues equivalent to Ser-303 and Ser-337 of the amino acid sequence represented by UniProtKB:P47074. Example: UniProtKB:P47074, Ser-303/Ser-337, MOD:00046." [PMID:17504936, PRO:KER]

organism-modification


PR:000035503
spindle assembly checkpoint component MAD3 phosphorylated 2 (yeast)
yMAD3/Phos:2
"A spindle assembly checkpoint component MAD3 phosphorylated 2 in yeast. Phosphorylation is necessary for normal response to a lack of kinetochore tension but not for response to lack of microtubule binding to kinetochores. In addition to the phosphorylation annotated, this form might also be phosphorylated on Ser-10 and Ser-486. UniProtKB:P47074, Ser-303/Ser-337, MOD:00046." [PMID:17504936, PRO:KER]
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035503 yMAD3/Phos:2
UniProtKB:P47074, Ser-303/Ser-337, MOD:00046		 acts_upstream_of_or_withinincreased GO:0031577 spindle checkpoint signaling relative to PR:000035506 yMAD3 unphosphorylated PMID:17504936