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Protein Ontology report - tumor protein 63 isoform 2
PR:000035584 - http://purl.obolibrary.org/obo/PR_000035584
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035584   
  PRO nametumor protein 63 isoform 2 
  Synonyms
PRO-Short-label: EXACT:TP63/iso:2
Other: EXACT:p63 DeltaN-alpha
  Definition"A tumor protein 63 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O88898-2 or a 1:1 ortholog thereof. This form is produced by alternative promoter usage." [PMID:9703973, PMID:9774969, PRO:HJD] 
  PRO Categorysequence 
  ParentPR:000016567 tumor protein 63
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000035584 tumor protein 63 isoform 2
TP63/iso:2

organism-sequence


PR:O88898-2 tumor protein 63 isoform 2 (mouse)
mTP63/iso:2
Yes
organism-sequence


PR:Q9H3D4-2 tumor protein 63 isoform 2 (human)
hTP63/iso:2

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:O88898-2 mTP63/iso:2 acts_upstream_of_or_withinGO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3623698; PMID:16618808
GO:0000122 negative regulation of transcription by RNA polymerase II MGI_ref:3623698; PMID:16618808
GO:0002064 epithelial cell development MGI_ref:3761221; PMID:16601749
GO:0008544 epidermis development MGI_ref:3761221; PMID:16601749
GO:0043616 keratinocyte proliferation MGI_ref:3761221; PMID:16601749
GO:0045617 negative regulation of keratinocyte differentiation MGI_ref:3623698; PMID:16618808
GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3794467; PMID:18326838
GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3794467; PMID:18326838
GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3794467; PMID:18326838
GO:0045944 positive regulation of transcription by RNA polymerase II MGI_ref:3794467; PMID:18326838
enablesGO:0003682 chromatin binding MGI_ref:3761221; PMID:16601749
GO:0043565 sequence-specific DNA binding MGI_ref:3794467; PMID:18326838
GO:0043565 sequence-specific DNA binding MGI_ref:3794467; PMID:18326838
located_inGO:0005634 nucleus MGI_ref:3761221; PMID:16601749