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Protein Ontology report - disrupted in schizophrenia 1 protein isoform 1
PR:000035601 - http://purl.obolibrary.org/obo/PR_000035601
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000035601   
  PRO namedisrupted in schizophrenia 1 protein isoform 1 
  Synonyms
PRO-Short-label: EXACT:DISC1/iso:1
  Definition"A disrupted in schizophrenia 1 protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q811T9-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000006494 disrupted in schizophrenia 1 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification2                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000035601 disrupted in schizophrenia 1 protein isoform 1
DISC1/iso:1

organism-sequence


PR:Q811T9-1 disrupted in schizophrenia 1 protein isoform 1 (mouse)
mDISC1/iso:1

organism-modification


PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)
mDISC1/iso:1/Phos:1
Yes
organism-modification


PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)
mDISC1/iso:1/PhosRes-
Yes
modification


PR:000035600 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1
DISC1/iso:1/Phos:1

organism-modification


PR:000035602 disrupted in schizophrenia 1 protein isoform 1 phosphorylated 1 (mouse)
mDISC1/iso:1/Phos:1
Yes
modification


PR:000035653 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form
DISC1/iso:1/PhosRes-

organism-modification


PR:000035654 disrupted in schizophrenia 1 protein isoform 1 unphosphorylated form (mouse)
mDISC1/iso:1/PhosRes-
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035602 mDISC1/iso:1/Phos:1
UniProtKB:Q811T9-1, Ser-710, MOD:00046		 acts_upstream_of_or_withinGO:0008104 intracellular protein localization MGI_ref:5002731; PMID:21471969
enablesGO:0005515 protein binding with PR:Q3V3N7 Bardet-Biedl syndrome 1 protein homolog (mouse) MGI_ref:5002731; PMID:21471969
located_inGO:0005813 centrosome MGI_ref:5002731; PMID:21471969
PR:000035654 mDISC1/iso:1/PhosRes- acts_upstream_of_or_withinGO:0060070 canonical Wnt signaling pathway MGI_ref:5002731; PMID:21471969
enablesGO:0005515 protein binding with PR:Q9WV60 GSK-3 beta (mouse) MGI_ref:5002731; PMID:21471969