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RACE-PRO
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Protein Ontology report - presenilin-2 isoform PS2short
PR:000036857 -
http://purl.obolibrary.org/obo/PR_000036857
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000036857
PRO name
presenilin-2 isoform PS2short
Synonyms
PRO-Short-label
:
EXACT:
PSEN2/iso:PS2short
Definition
"A presenilin-2 that is a translation product of some mRNA produced by alternative promoter usage, giving rise to a protein with the amino acid sequence represented by residues 298 to 448 in
UniProtKB:Q61144
or a 1:1 ortholog thereof." [
PMID:9353287
, PRO:CNA]
PRO Category
sequence
Parent
PR:000013345
presenilin-2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
1
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000036857
presenilin-2 isoform PS2short
PSEN2/iso:PS2short
"A presenilin-2 that is a translation product of some mRNA produced by alternative promoter usage, giving rise to a protein with the amino acid sequence represented by residues 298 to 448 in UniProtKB:Q61144 or a 1:1 ortholog thereof." [PMID:9353287, PRO:CNA]
organism-sequence
PR:000036858
presenilin-2 isoform PS2short (mouse)
mPSEN2/iso:PS2short
"A presenilin-2 isoform PS2short that is encoded in the genome of mouse. UniProtKB:Q61144-1, 298-448." [PMID:9353287, PRO:KRC]
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036858
mPSEN2/iso:PS2short
UniProtKB:Q61144-1, 298-448
acts_upstream_of_or_within
GO:1902042
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
MGI_ref:1099227;
PMID:9353287