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Protein Ontology report - myristoylated protein

PR:000037075 - http://purl.obolibrary.org/obo/PR_000037075

Protein Forms

Complex

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000037075

PRO name

myristoylated protein

Synonyms

PRO-Short-label:

EXACT:

Prot/MyrRes+

Definition

"A protein that includes at least one myristoylated residue." [PRO:DAN]

PRO Category

modification

Parent

PR:000000001 protein

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Modification	12	Organism-Modification	35

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

modification

PR:000037075 myristoylated protein

Prot/MyrRes+

modification

PR:000000496 tumor necrosis factor isoform 1 myristoylated form

TNF/iso:1/MyrRes+

modification

PR:000000606 tumor necrosis factor isoform 1 myristoylated 1

TNF/iso:1/Myr:1

organism-modification

PR:000036507 tumor necrosis factor isoform 1 myristoylated 1 (human)

hTNF/iso:1/Myr:1

Yes

modification

PR:000001259 interleukin-1 alpha isoform 1 myristoylated form

IL1A/iso:1/MyrRes+

modification

PR:000001268 interleukin-1 alpha isoform 1 myristoylated 1

IL1A/iso:1/Myr:1

organism-modification

PR:000036598 interleukin-1 alpha isoform 1 myristoylated 1 (human)

hIL1A/iso:1/Myr:1

Yes

modification

PR:000001269 interleukin-1 alpha isoform 1 myristoylated 2

IL1A/iso:1/Myr:2

organism-modification

PR:000036599 interleukin-1 alpha isoform 1 myristoylated 2 (human)

hIL1A/iso:1/Myr:2

Yes

modification

PR:000027200 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated form

TICAM2/iso:1/InitMet-/MyrRes+

organism-modification

PR:000027201 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated 1 (human)

hTICAM2/iso:1/InitMet-/Myr:1

organism-modification

PR:000040891 TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated and phosphorylated 1 (human)

hTICAM2/iso:1/InitMet-/MyrPhos:1

Yes

modification

PR:000028844 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 myristoylated 1

SH3TC2/iso:1/Myr:1

organism-modification

PR:000028845 SH3 domain and tetratricopeptide repeat-containing protein 2 isoform 1 myristoylated 1 (mouse)

mSH3TC2/iso:1/Myr:1

Yes

modification

PR:000035651 cystin-1 isoform 1, N-terminal myristoylated form

CYS1/iso:1/MyrRes+

organism-modification

PR:000035652 cystin-1 isoform 1, N-terminal myristoylated form (mouse)

mCYS1/iso:1/MyrRes+

Yes

modification

PR:000036377 protein phosphatase 1A isoform 1 myristoylated 1

PPM1A/iso:1/Myr:1

organism-modification

PR:000036378 protein phosphatase 1A isoform 1 myristoylated 1 (mouse)

mPPM1A/iso:1/Myr:1

modification

PR:000036379 protein phosphatase 1B, initiator methionine removed myristoylated 1

PPM1B/InitMet-/Myr:1

organism-modification

PR:000036380 protein phosphatase 1B, initiator methionine removed myristoylated 1 (mouse)

mPPM1B/InitMet-/Myr:1

modification

PR:000036788 mitochondrial peptide methionine sulfoxide reductase isoform 2, initiator methionine removed myristoylated 1

MSRA/iso:2/InitMet-/Myr:1

organism-modification

PR:000036789 mitochondrial peptide methionine sulfoxide reductase isoform 2, initiator methionine removed myristoylated 1 (mouse)

mMSRA/iso:2/InitMet-/Myr:1

organism-modification

PR:000037110 protein XRP2 myristoylated 1 (human)

hRP2/Myr:1

organism-modification

PR:000044864 nephrocystin-3 isoform m1, initiator methionine removed myristoylated 1 (mouse)

mNPHP3/iso:m1/InitMet-/Myr:1

organism-modification

PR:000060301 tyrosine-protein kinase Fyn, initiator methionine removed myristoylated and phosphorylated 1 (human)

hFYN/InitMet-/MyrPhos:1

organism-modification

PR:000060310 proto-oncogene tyrosine-protein kinase Src, initiator methionine removed myristoylated and phosphorylated 1 (human)

hSRC/InitMet-/MyrPhos:1

organism-modification

PR:000060424 tyrosine-protein kinase Yes, initiator methionine removed myristoylated and phosphorylated 1 (human)

hYES1/InitMet-/MyrPhos:1

organism-modification

PR:000060696 NADH-cytochrome b5 reductase 3, initiator methionine removed myristoylated 1 (human)

hCYB5R3/InitMet-/Myr:1

organism-modification

PR:000060707 tyrosine-protein kinase Fyn, initiator methionine removed myristoylated and palmitoylated 1 (human)

hFYN/InitMet-/MyrPalm:1

organism-modification

PR:000060868 cystin-1, initiator methionine removed myristoylated 1 (human)

hCYS1/InitMet-/Myr:1

organism-modification

PR:000061191 tyrosine-protein kinase Fyn isoform 1, initiator methionine removed myristoylated and phosphorylated 1 (human)

hFYN/iso:1/InitMet-/MyrPhos:1

organism-modification

PR:000061276 tyrosine-protein kinase Fyn isoform 1, initiator methionine removed myristoylated 1 (human)

hFYN/iso:1/InitMet-/Myr:1

organism-modification

PR:000061483 nitric oxide synthase 3, initiator methionine removed myristoylated 1 (human)

hNOS3/InitMet-/Myr:1

organism-modification

PR:000061586 nitric oxide synthase 3, initiator methionine removed myristoylated and palmitoylated 1 (human)

hNOS3/InitMet-/MyrPalm:1

organism-modification

PR:000061886 ADP-ribosylation factor-like protein 1, initiator methionine removed myristoylated 1 (human)

hARL1/InitMet-/Myr:1

organism-modification

PR:000062632 nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 1 (human)

hNOS3/InitMet-/MyrPalmPhos:1

organism-modification

PR:000062759 DCN1-like protein 3, initiator methionine removed myristoylated 1 (human)

hDCUN1D3/InitMet-/Myr:1

organism-modification

PR:000063296 proto-oncogene tyrosine-protein kinase Src, initiator methionine removed myristoylated 1 (human)

hSRC/InitMet-/Myr:1

organism-modification

PR:000063476 tyrosine-protein kinase Lyn, initiator methionine removed myristoylated and palmitoylated 1 (human)

hLYN/InitMet-/MyrPalm:1

organism-modification

PR:000063550 proto-oncogene tyrosine-protein kinase Src, initiator methionine removed myristoylated and phosphorylated 2 (human)

hSRC/InitMet-/MyrPhos:2

organism-modification

PR:000063555 ADP-ribosylation factor 4, initiator methionine removed myristoylated 1 (human)

hARF4/InitMet-/Myr:1

organism-modification

PR:000063633 tyrosine-protein kinase Blk, initiator methionine removed myristoylated 1 (human)

hBLK/InitMet-/Myr:1

organism-modification

PR:000063665 TIR domain-containing adapter molecule 2, initiator methionine removed myristoylated and phosphorylated 1 (human)

hTICAM2/InitMet-/MyrPhos:1

organism-modification

PR:000063993 nephrocystin-3, initiator methionine removed myristoylated 1 (human)

hNPHP3/InitMet-/Myr:1

organism-modification

PR:000064499 cyclin-dependent kinase 5 activator 1, initiator methionine removed myristoylated 1 (human)

hCDK5R1/InitMet-/Myr:1

organism-modification

PR:000085916 nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 2 (human)

hNOS3/InitMet-/MyrPalmPhos:2

organism-modification

PR:000085948 nitric oxide synthase 3, initiator methionine removed myristoylated, palmitoylated, and phosphorylated 3 (human)

hNOS3/InitMet-/MyrPalmPhos:3

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Prot/MyrRes+ forms found in complexes

Prot/MyrRes+ Component	Complexes
PR:000040891 hTICAM2/iso:1/InitMet-/MyrPhos:1	PR:000027208 ticam1:ticam2:activated TLR4 complex (human)
	PR:000028678 ticam2:activated TLR4 complex (human)
	PR:000028680 traf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035715 pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035734 free K63-linked pUb:TAK1complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000035738 free K63-linked pUb:activated TAK1 complex:pUbtraf6:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036022 traf3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036024 rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036027 sarm:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036041 K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036049 K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036053 IKK complex:K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036056 rip3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036058 rip1:rip3:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
	PR:000036123 p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)
	PR:000036124 p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex complex (human)

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000028845 mSH3TC2/iso:1/Myr:1 UniProtKB:Q80VA5-1, 2-1289, Gly-2, MOD:00068	located_in	GO:0005886 plasma membrane	MGI_ref:4366127; PMID:19805030
	located_in	GO:0055037 recycling endosome	PMID:19805030
PR:000035652 mCYS1/iso:1/MyrRes+ UniProtKB:Q8R4T1-1, 2-145, Gly-2, MOD:00068	located_in	GO:0005930 axoneme	MGI_ref:4461844; PMID:19850956
	located_in	GO:0045121 membrane raft	MGI_ref:4461844; PMID:19850956
PR:000036507 hTNF/iso:1/Myr:1 UniProtKB:P01375-1, Lys-19/Lys-20, MOD:00087	located_in	GO:0016020 membrane	PMID:1402651
PR:000036598 hIL1A/iso:1/Myr:1 UniProtKB:P01583-1, Lys-83, MOD:00087	located_in	GO:0016020 membrane	PMID:8346241
PR:000036599 hIL1A/iso:1/Myr:2 UniProtKB:P01583-1, Lys-82, MOD:00087	located_in	GO:0016020 membrane	PMID:8346241