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Protein Ontology report - vascular endothelial growth factor A, long form isoform 2
PR:000037370 - http://purl.obolibrary.org/obo/PR_000037370
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037370   
  PRO namevascular endothelial growth factor A, long form isoform 2 
  Synonyms
PRO-Short-label: EXACT:VEGFA/iso:2
Other: RELATED:VEGF164
  Definition"A vascular endothelial growth factor A, long form that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q00731-2 or a 1:1 ortholog thereof." [PMID:8614412, PRO:KRC] 
  PRO Categorysequence 
  ParentPR:000017284 vascular endothelial growth factor A, long form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?
sequence



PR:000037370 vascular endothelial growth factor A, long form isoform 2

VEGFA/iso:2


organism-sequence



PR:P16612-2 vascular endothelial growth factor A isoform 2 (rat)

rVEGFA/iso:2


organism-sequence



PR:Q00731-2 vascular endothelial growth factor A, long form isoform 2 (mouse)

mVEGFA/iso:2

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:Q00731-2 mVEGFA/iso:2 acts_upstream_of_or_withinGO:0001525 angiogenesis MGI_ref:3758404; PMID:17626017
GO:0001569 branching involved in blood vessel morphogenesis MGI_ref:3710026; PMID:17428830
GO:0001938 positive regulation of endothelial cell proliferation MGI_ref:74931; PMID:1592003
GO:0002053 positive regulation of mesenchymal cell proliferation MGI_ref:3613102; PMID:16375885
GO:0030324 lung development MGI_ref:3613102; PMID:16375885
GO:0048010 vascular endothelial growth factor receptor signaling pathway MGI_ref:74931; PMID:1592003
GO:0048754 branching morphogenesis of an epithelial tube MGI_ref:3613102; PMID:16375885
GO:0060426 lung vasculature development MGI_ref:1927039; PMID:11066091
enablesGO:0005102 signaling receptor binding MGI_ref:3758404; PMID:17626017
GO:0005515 protein binding MGI_ref:1860784; PMID:10705382
GO:0008201 heparin binding MGI_ref:77585; PMID:8614412
GO:0008201 heparin binding MGI_ref:77585; PMID:8614412
GO:0043183 vascular endothelial growth factor receptor 1 binding MGI_ref:3758404; PMID:17626017
GO:0043184 vascular endothelial growth factor receptor 2 binding MGI_ref:1860784; PMID:10705382
GO:0043184 vascular endothelial growth factor receptor 2 binding MGI_ref:1860784; PMID:10705382
GO:0050840 extracellular matrix binding MGI_ref:3758404; PMID:17626017
located_inGO:0005576 extracellular region MGI_ref:77585; PMID:8614412