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Documentation
Protein Ontology report - vascular endothelial growth factor A, long form isoform 2
PR:000037370 -
http://purl.obolibrary.org/obo/PR_000037370
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000037370
PRO name
vascular endothelial growth factor A, long form isoform 2
Synonyms
PRO-Short-label
:
EXACT:
VEGFA/iso:2
Other
:
RELATED:
VEGF164
Definition
"A vascular endothelial growth factor A, long form that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q00731-2
or a 1:1 ortholog thereof." [
PMID:8614412
, PRO:KRC]
PRO Category
sequence
Parent
PR:000017284
vascular endothelial growth factor A, long form
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
0
Organism-Modification
0
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000037370
vascular endothelial growth factor A, long form isoform 2
VEGFA/iso:2
organism-sequence
PR:P16612-2
vascular endothelial growth factor A isoform 2 (rat)
rVEGFA/iso:2
organism-sequence
PR:Q00731-2
vascular endothelial growth factor A, long form isoform 2 (mouse)
mVEGFA/iso:2
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:Q00731-2
mVEGFA/iso:2
acts_upstream_of_or_within
GO:0001525
angiogenesis
MGI_ref:3758404;
PMID:17626017
GO:0001569
branching involved in blood vessel morphogenesis
MGI_ref:3710026;
PMID:17428830
GO:0001938
positive regulation of endothelial cell proliferation
MGI_ref:74931;
PMID:1592003
GO:0002053
positive regulation of mesenchymal cell proliferation
MGI_ref:3613102;
PMID:16375885
GO:0030324
lung development
MGI_ref:3613102;
PMID:16375885
GO:0048010
vascular endothelial growth factor receptor signaling pathway
MGI_ref:74931;
PMID:1592003
GO:0048754
branching morphogenesis of an epithelial tube
MGI_ref:3613102;
PMID:16375885
GO:0060426
lung vasculature development
MGI_ref:1927039;
PMID:11066091
enables
GO:0005102
signaling receptor binding
MGI_ref:3758404;
PMID:17626017
GO:0005515
protein binding
MGI_ref:1860784;
PMID:10705382
GO:0008201
heparin binding
MGI_ref:77585;
PMID:8614412
GO:0008201
heparin binding
MGI_ref:77585;
PMID:8614412
GO:0043183
vascular endothelial growth factor receptor 1 binding
MGI_ref:3758404;
PMID:17626017
GO:0043184
vascular endothelial growth factor receptor 2 binding
MGI_ref:1860784;
PMID:10705382
GO:0043184
vascular endothelial growth factor receptor 2 binding
MGI_ref:1860784;
PMID:10705382
GO:0050840
extracellular matrix binding
MGI_ref:3758404;
PMID:17626017
located_in
GO:0005576
extracellular region
MGI_ref:77585;
PMID:8614412