Protein Ontology

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Protein Ontology report - murine-type cathepsin L

PR:000040360 - http://purl.obolibrary.org/obo/PR_000040360

Protein Forms

Annotations

Ontology Information

Show OBO stanza

PRO ID

PR:000040360

PRO name

murine-type cathepsin L

Synonyms

PRO-Short-label:

EXACT:

murine-Ctsl

Definition

"A cathepsin-like protease that is a translation product of the mouse Ctsl gene or a 1:1 ortholog thereof." [PRO:DAN]

Comment

Note: Murine Ctsl genes are more closely related to the human CTSV gene than to the human CTSL gene.

PRO Category

gene

Parent

PR:000040662 cathepsin-like protease

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	1	Organism-Gene	2
Sequence	7	Organism-Sequence	7
Modification	1	Organism-Modification	1

Term Hierarchy
Visualization

DAG:

OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

gene

PR:000040360 murine-type cathepsin L

murine-Ctsl

organism-gene

PR:P06797 procathepsin L (mouse)

mCtsl

organism-seqgroup

PR:000037136 cathepsin L short form (mouse)

mCtsl/iso:[2/3/4/5/6/7]

Yes

organism-sequence

PR:000037114 procathepsin L isoform 2 (mouse)

mCtsl/iso:2

organism-sequence

PR:000037116 procathepsin L isoform 3 (mouse)

mCtsl/iso:3

organism-sequence

PR:000037118 procathepsin L isoform 4 (mouse)

mCtsl/iso:4

organism-sequence

PR:000037120 procathepsin L isoform 5 (mouse)

mCtsl/iso:5

organism-sequence

PR:000037122 procathepsin L isoform 6 (mouse)

mCtsl/iso:6

organism-sequence

PR:000037124 procathepsin L isoform 7 (mouse)

mCtsl/iso:7

organism-sequence

PR:000037114 procathepsin L isoform 2 (mouse)

mCtsl/iso:2

organism-sequence

PR:000037116 procathepsin L isoform 3 (mouse)

mCtsl/iso:3

organism-sequence

PR:000037118 procathepsin L isoform 4 (mouse)

mCtsl/iso:4

organism-sequence

PR:000037120 procathepsin L isoform 5 (mouse)

mCtsl/iso:5

organism-sequence

PR:000037122 procathepsin L isoform 6 (mouse)

mCtsl/iso:6

organism-sequence

PR:000037124 procathepsin L isoform 7 (mouse)

mCtsl/iso:7

organism-sequence

PR:P06797-1 procathepsin L isoform 1 (mouse)

mCtsl/iso:1

Yes

organism-modification

PR:000037126 procathepsin L isoform 1, signal peptide removed form (mouse)

mCtsl/iso:1/SigPep-

organism-gene

PR:P07154 procathepsin L (rat)

rCtsl

sequence

PR:000037111 murine-type cathepsin L isoform 1

murine-Ctsl/iso:1

organism-sequence

PR:P06797-1 procathepsin L isoform 1 (mouse)

mCtsl/iso:1

Yes

organism-modification

PR:000037126 procathepsin L isoform 1, signal peptide removed form (mouse)

mCtsl/iso:1/SigPep-

modification

PR:000037125 murine-type cathepsin L isoform 1, signal peptide removed form

murine-Ctsl/iso:1/SigPep-

organism-modification

PR:000037126 procathepsin L isoform 1, signal peptide removed form (mouse)

mCtsl/iso:1/SigPep-

sequence

PR:000037113 murine-type cathepsin L isoform 2

murine-Ctsl/iso:2

organism-sequence

PR:000037114 procathepsin L isoform 2 (mouse)

mCtsl/iso:2

sequence

PR:000037115 murine-type cathepsin L isoform 3

murine-Ctsl/iso:3

organism-sequence

PR:000037116 procathepsin L isoform 3 (mouse)

mCtsl/iso:3

sequence

PR:000037117 murine-type cathepsin L isoform 4

murine-Ctsl/iso:4

organism-sequence

PR:000037118 procathepsin L isoform 4 (mouse)

mCtsl/iso:4

sequence

PR:000037119 murine-type cathepsin L isoform 5

murine-Ctsl/iso:5

organism-sequence

PR:000037120 procathepsin L isoform 5 (mouse)

mCtsl/iso:5

sequence

PR:000037121 murine-type cathepsin L isoform 6

murine-Ctsl/iso:6

organism-sequence

PR:000037122 procathepsin L isoform 6 (mouse)

mCtsl/iso:6

sequence

PR:000037123 murine-type cathepsin L isoform 7

murine-Ctsl/iso:7

organism-sequence

PR:000037124 procathepsin L isoform 7 (mouse)

mCtsl/iso:7

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000037136 mCtsl/iso:[2/3/4/5/6/7]	acts_upstream_of_or_within	GO:0016485 protein processing	MGI_ref:3044037; PMID:15099520
		GO:0016485 protein processing	MGI_ref:3044037; PMID:15099520
		GO:0032956 regulation of actin cytoskeleton organization	MGI_ref:5297732; PMID:21911934
	located_in	GO:0005634 nucleus	MGI_ref:5297732; PMID:21911934
	located_in	GO:0005634 nucleus	MGI_ref:5297732; PMID:21911934
PR:P06797-1 mCtsl/iso:1	acts_upstream_of_or_within	GO:0016540 protein autoprocessing	MGI_ref:5513110; PMID:1482371