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Protein Ontology report - CEACAM1a-2C1, signal peptide removed N-glycosylasparagine form (mouse)
PR:000044470 -
http://purl.obolibrary.org/obo/PR_000044470
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000044470
PRO name
CEACAM1a-2C1, signal peptide removed N-glycosylasparagine form (mouse)
Synonyms
PRO-Short-label
:
EXACT:
mCEACAM1a/iso:2C1/SigPep-/NGlycoAsn+
PRO-proteoform-std
:
EXACT:
UniProtKB:Q3LFS6
, 35-270,
MOD:00160
Definition
"A cell adhesion molecule CEACAM1, signal peptide removed form that is the signal cleavage product of isoform CEACAM1a-2C1 of allele CEACAM1a in mouse and includes at least one N-glycosylasparagine.
UniProtKB:Q3LFS6
, 35-270,
MOD:00160
." [
PMID:19358828
, PRO:KRC]
Comment
Evidence=(ECO:0000006, based on
PMID:19358828
). Note:
PMID:19358828
in figure 2B shows in vitro expression of Ceacam1a-2, Ceacam1a-2C1 and Ceacam1a-4C1 isoforms by BHK transfectants followed by immunoprecipitation and Western blotting detects these Ceacam1 isoforms at approximately 55, 45, and 120 kDa, respectively. While the authors do not explicitly mention glycosylation, these sizes are consistent with weights of glycosylated forms and not with predicted weights of unmodified isoforms.
PRO Category
organism-modification
Parent
PR:000018399
cell adhesion molecule CEACAM1, signal peptide removed form
PR:000037069
glycoprotein
PR:P31809
cell adhesion molecule CEACAM1 (mouse)
Taxon
NCBITaxon:10090
Mus musculus
Term Hierarchy
Visualization
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Functional Annotation (PRO-centric view)
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PRO Term
GO Annotation
Evidence
PR:000044470
mCEACAM1a/iso:2C1/SigPep-/NGlycoAsn+
UniProtKB:Q3LFS6, 35-270, MOD:00160
located_in
GO:0005615
extracellular space
MGI_ref:3848729;
PMID:19358828