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Protein Ontology report - CEACAM1a-4 N-glycosylasparagine form (mouse)

PR:000044489 - http://purl.obolibrary.org/obo/PR_000044489

Protein Forms

Annotations

Ontology Information

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PAF

GPI

PRO ID

PR:000044489

PRO name

CEACAM1a-4 N-glycosylasparagine form (mouse)

Synonyms

PRO-Short-label:

EXACT:

mCEACAM1a/iso:4/NGlycoAsp+

Definition

"A cell adhesion molecule CEACAM1, signal peptide removed form that is the signal cleavage product of allele CEACAM1a in mouse with four copies of the Ig domain and includes at least one N-glycosylasparagine." [PRO:KRC]

PRO Category

union

Parent

PR:000018399 cell adhesion molecule CEACAM1, signal peptide removed form
PR:000037069 glycoprotein
PR:P31809 cell adhesion molecule CEACAM1 (mouse)

Taxon

NCBITaxon:10090 Mus musculus

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms

Term Hierarchy
Visualization

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OLS:

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Protein Forms

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Category

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?

union

PR:000044489 CEACAM1a-4 N-glycosylasparagine form (mouse)

mCEACAM1a/iso:4/NGlycoAsp+

Yes

organism-modification

PR:000044463 CEACAM1a-4L, signal peptide removed N-glycosylasparagine form (mouse)

mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+

organism-modification

PR:000044465 CEACAM1a-4S, signal peptide removed N-glycosylasparagine form (mouse)

mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000044463 mCEACAM1a/iso:4L/SigPep-/NGlycoAsn+ UniProtKB:P31809-1, 35-521, MOD:00160	acts_upstream_of_or_within	GO:0032703 negative regulation of interleukin-2 production	MGI_ref:3693042; PMID:17081782
		GO:0042130 negative regulation of T cell proliferation	MGI_ref:5451119; PMID:23123061
		GO:0042130 negative regulation of T cell proliferation	MGI_ref:5451119; PMID:23123061
	located_in	GO:0009897 external side of plasma membrane	MGI_ref:3693042; PMID:17081782
PR:000044465 mCEACAM1a/iso:4S/SigPep-/NGlycoAsn+ UniProtKB:P31809-2, 35-458, MOD:00160	acts_upstream_of_or_within	GO:0002639 positive regulation of immunoglobulin production	MGI_ref:5451119; PMID:23123061
		GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	MGI_ref:5608586; PMID:1633107
		GO:0042102 positive regulation of T cell proliferation	MGI_ref:5451119; PMID:23123061
		GO:0046718 symbiont entry into host cell	MGI_ref:49235; PMID:1719235
		GO:0048541 Peyer's patch development	MGI_ref:5451119; PMID:23123061
		GO:0070237 positive regulation of activation-induced cell death of T cells	MGI_ref:5451119; PMID:23123061
		GO:0070886 positive regulation of calcineurin-NFAT signaling cascade	MGI_ref:5451119; PMID:23123061
		GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation	MGI_ref:5451119; PMID:23123061
		GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation	MGI_ref:5451119; PMID:23123061
		GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation	MGI_ref:5451119; PMID:23123061
	enables	GO:0001618 virus receptor activity	MGI_ref:49235; PMID:1719235
	enables	GO:0046790 virion binding	MGI_ref:3053174; PMID:8380065
	located_in	GO:0009897 external side of plasma membrane	MGI_ref:81180; PMID:8896983
	located_in	GO:0009897 external side of plasma membrane	MGI_ref:81180; PMID:8896983
PR:000044489 mCEACAM1a/iso:4/NGlycoAsp+	acts_upstream_of_or_within	GO:0044794 host-mediated activation of viral process	MGI_ref:2148352; PMID:11483763
	enables	NOT GO:0001618 virus receptor activity	MGI_ref:5608587; PMID:2164599
	located_in	GO:0016020 membrane	MGI_ref:73162; PMID:1648219
		GO:0016020 membrane	MGI_ref:73162; PMID:1648219
		GO:0016020 membrane	MGI_ref:73162; PMID:1648219
		GO:0031526 brush border membrane	MGI_ref:73162; PMID:1648219