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Protein Ontology report - store-operated ion channel protein
PR:000044627 - http://purl.obolibrary.org/obo/PR_000044627
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000044627   
  PRO namestore-operated ion channel protein 
  Synonyms
Other: EXACT:capacitative calcium channel protein | SOC channel protein | store-operated calcium channel protein
  Definition"An ion channel protein that has store-operated calcium channel activity. Store-operated calcium channels transport calcium in response to emptying of intracellular calcium stores." [GO:0015279, PRO:XQ] 
  PRO Categoryfamily 
  ParentPR:000049983 ion channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family2                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 11                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000044627

store-operated ion channel protein

fam:orai_chan


"An ion channel protein that has store-operated calcium channel activity. Store-operated calcium channels transport calcium in response to emptying of intracellular calcium stores." [GO:0015279, PRO:XQ]


family



PR:000044626

orai channel protein

fam:orai_chan


"A store-operated ion channel protein that is a translation product of the human ORAI1, ORAI2, or ORAI3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:XQ]


gene



PR:000012027

calcium release-activated calcium channel protein 1

ORAI1


"An orai channel protein that is a translation product of the human ORAI1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q5M848

calcium release-activated calcium channel protein 1 (rat)

rORAI1


"A calcium release-activated calcium channel protein 1 that is encoded in the genome of rat." [OMA:Q5M848, PRO:DNx]


organism-gene



PR:Q5ZL05

calcium release-activated calcium channel protein 1 (chicken)

chick-ORAI1


"A calcium release-activated calcium channel protein 1 that is encoded in the genome of chicken." [OMA:Q5ZL05, PRO:DNx]


organism-gene



PR:Q6TLE6

calcium release-activated calcium channel protein 1 (zebrafish)

z-ORAI1


"A calcium release-activated calcium channel protein 1 that is encoded in the genome of zebrafish." [PRO:DNx]


organism-gene



PR:Q8BWG9

calcium release-activated calcium channel protein 1 (mouse)

mORAI1


"A calcium release-activated calcium channel protein 1 that is encoded in the genome of mouse." [OMA:Q8BWG9, PRO:DNx]


organism-gene



PR:Q96D31

calcium release-activated calcium channel protein 1 (human)

hORAI1


"A calcium release-activated calcium channel protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96D31]


organism-sequence



PR:Q96D31-1

calcium release-activated calcium channel protein 1 isoform alpha (human)

hORAI1/iso:alpha


"A calcium release-activated calcium channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96D31-1." [PRO:DNx, UniProtKB:Q96D31]


organism-sequence



PR:Q96D31-2

calcium release-activated calcium channel protein 1 isoform beta (human)

hORAI1/iso:beta


"A calcium release-activated calcium channel protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96D31-2." [PRO:DNx, UniProtKB:Q96D31]


organism-modification



PR:000046023

calcium release-activated calcium channel protein 1 phosphorylated 1 (human)

hORAI1/Phos:1


"A calcium release-activated calcium channel protein 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-34 of the amino acid sequence represented by UniProtKB:Q96D31-1. Example: UniProtKB:Q96D31-1, Ser-34, MOD:00046." [iPTMnet:Q96D31, PMID:26269433]


organism-modification



PR:000071934

calcium release-activated calcium channel protein 1 cysteinylated 1 (human)

hORAI1/Cyst:1


"A calcium release-activated calcium channel protein 1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-143 of the amino acid sequence represented by UniProtKB:Q96D31-1. Example: UniProtKB:Q96D31-1, Cys-143, MOD:00765." [IEDB_epitope:1004053, PRO:DNx]


gene



PR:000012028

protein orai-3

ORAI3


"An orai channel protein that is a translation product of the human ORAI3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q6AXR8

protein orai-3 (rat)

rORAI3


"A protein orai-3 that is encoded in the genome of rat." [OMA:Q6AXR8, PRO:DNx]


organism-gene



PR:Q6P8G8

protein orai-3 (mouse)

mORAI3


"A protein orai-3 that is encoded in the genome of mouse." [OMA:Q6P8G8, PRO:DNx]


organism-gene



PR:Q9BRQ5

protein orai-3 (human)

hORAI3


"A protein orai-3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9BRQ5]


organism-modification



PR:000057988

protein orai-3 O-glycosylated 1 (human)

hORAI3/OGlyco:1


"A protein orai-3 (human) that has been O-glycosylated at the residue equivalent to Ser-205 of the amino acid sequence represented by UniProtKB:Q9BRQ5-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9BRQ5-1, Ser-205, MOD:00002~GNO:G43417UB." [GlyGen:Q9BRQ5-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000057989

protein orai-3 O-glycosylated 2 (human)

hORAI3/OGlyco:2


"A protein orai-3 (human) that has been O-glycosylated at the residue equivalent to Ser-216 of the amino acid sequence represented by UniProtKB:Q9BRQ5-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q9BRQ5-1, Ser-216, MOD:00002~GNO:G43417UB." [GlyGen:Q9BRQ5-1, PMID:30459171, PRO:DNx]


organism-modification



PR:000069250

protein orai-3 cysteinylated 1 (human)

hORAI3/Cyst:1


"A protein orai-3 (human) that has been cysteinylated on the residue at the position equivalent to Cys-118 of the amino acid sequence represented by UniProtKB:Q9BRQ5. UniProtKB:Q9BRQ5, Cys-118, MOD:00765." [IEDB_epitope:924912, PRO:DNx]


gene



PR:000031378

protein orai-2

ORAI2


"An orai channel protein that is a translation product of the human ORAI2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q5ZLW2

protein orai-2 (chicken)

chick-ORAI2


"A protein orai-2 that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:Q8BH10

protein orai-2 (mouse)

mORAI2


"A protein orai-2 that is encoded in the genome of mouse." [OMA:Q8BH10, PRO:DNx]


organism-gene



PR:Q96SN7

protein orai-2 (human)

hORAI2


"A protein orai-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96SN7]


organism-modification



PR:000077886

protein orai-2 deaminated 1 (human)

hORAI2/Deam:1


"A protein orai-2 (human) that has been deaminated on the residue at the position equivalent to Gln-46 of the amino acid sequence represented by UniProtKB:Q96SN7. UniProtKB:Q96SN7, Gln-46, MOD:00685." [IEDB_epitope:1800843, PRO:DNx]