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family
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PR:000044645 |
CatSper channel protein
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fam:CatSper_chan
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"A voltage-gated ion channel protein that is a translation product of the human CATSPER1, CATSPER2, CATSPER3, CATSPER4, CATSPERB, CATSPERD, CATSPERE, CATSPERG, or CATSPERZ genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:XQ]
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gene
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PR:000000669 |
cation channel sperm-associated protein 1
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CATSPER1
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"A CatSper channel protein that is a translation product of the human CATSPER1 gene or a 1:1 ortholog thereof. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel. CatSper channels seem to require auxiliary subunits, such as CatSperB (PR:000000672). In common with other channels, CatSper1 proteins have an architecture consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane. Unique to this class is the His-rich N terminus that seems to be involved the pH sensitivity of the channel calcium currents." [PRO:CNA]
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organism-gene
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PR:Q8NEC5 |
cation channel sperm-associated protein 1 (human)
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hCATSPER1
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"A cation channel sperm-associated protein 1 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q8NEC5]
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organism-sequence
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PR:Q8NEC5-1 |
cation channel sperm-associated protein 1 isoform 1 (human)
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hCATSPER1/iso:1
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"A cation channel sperm-associated protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8NEC5-1." [PRO:DNx, UniProtKB:Q8NEC5]
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Yes |
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organism-gene
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PR:Q91ZR5 |
cation channel sperm-associated protein 1 (mouse)
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mCATSPER1
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"A cation channel sperm-associated protein 1 that is encoded in the genome of mouse." [OMA:Q91ZR5, PRO:DNx]
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Yes |
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organism-sequence
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PR:Q91ZR5-1 |
cation channel sperm-associated protein 1 isoform 1 (mouse)
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mCATSPER1/iso:1
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"A cation channel sperm-associated protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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sequence
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PR:000000688 |
cation channel sperm-associated protein 1 isoform 1
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CATSPER1/iso:1
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"A cation channel sperm-associated protein 1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91ZR5-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q91ZR5-1 |
cation channel sperm-associated protein 1 isoform 1 (mouse)
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mCATSPER1/iso:1
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"A cation channel sperm-associated protein 1 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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modification
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PR:000002581 |
cation channel sperm-associated protein 1 isoform 1 unmodified form
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CATSPER1/iso:1/UnMod
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"A cation channel sperm-associated protein 1 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
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gene
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PR:000000670 |
cation channel sperm-associated protein 2
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CATSPER2
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"A CatSper channel protein that is a translation product of the human CATSPER2 gene or a 1:1 ortholog thereof. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel. CatSper channels seem to require auxiliary subunits, such as CatSperB (PR:000000672). In common with other channels, CatSper2 proteins have an architecture consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane." [PRO:CNA]
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organism-gene
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PR:A2ARP9 |
cation channel sperm-associated protein 2 (mouse)
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mCATSPER2
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"A cation channel sperm-associated protein 2 that is encoded in the genome of mouse." [OMA:A2ARP9, PRO:DNx]
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Yes |
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organism-sequence
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PR:A2ARP9-1 |
cation channel sperm-associated protein 2 isoform m1 (mouse)
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mCATSPER2/iso:m1
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"A cation channel sperm-associated protein 2 isoform m1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-gene
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PR:Q6AXP6 |
cation channel sperm-associated protein 2 (rat)
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rCATSPER2
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"A cation channel sperm-associated protein 2 that is encoded in the genome of rat." [OMA:Q6AXP6, PRO:DNx]
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organism-gene
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PR:Q96P56 |
cation channel sperm-associated protein 2 (human)
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hCATSPER2
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"A cation channel sperm-associated protein 2 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q96P56]
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organism-sequence
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PR:Q96P56-1 |
cation channel sperm-associated protein 2 isoform 1 (human)
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hCATSPER2/iso:1
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"A cation channel sperm-associated protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q96P56-2 |
cation channel sperm-associated protein 2 isoform 2 (human)
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hCATSPER2/iso:2
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"A cation channel sperm-associated protein 2 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q96P56-3 |
cation channel sperm-associated protein 2 isoform 3 (human)
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hCATSPER2/iso:3
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"A cation channel sperm-associated protein 2 isoform 3 that is encoded in the genome of human." [PRO:CNA]
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organism-sequence
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PR:Q96P56-4 |
cation channel sperm-associated protein 2 isoform h4 (human)
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hCATSPER2/iso:h4
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"A cation channel sperm-associated protein 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96P56-4." [PRO:DNx, UniProtKB:Q96P56]
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sequence
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PR:000000689 |
cation channel sperm-associated protein 2 isoform 1
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CATSPER2/iso:1
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"A cation channel sperm-associated protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96P56-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q96P56-1 |
cation channel sperm-associated protein 2 isoform 1 (human)
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hCATSPER2/iso:1
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"A cation channel sperm-associated protein 2 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
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sequence
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PR:000000690 |
cation channel sperm-associated protein 2 isoform 2
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CATSPER2/iso:2
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"A cation channel sperm-associated protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96P56-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q96P56-2 |
cation channel sperm-associated protein 2 isoform 2 (human)
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hCATSPER2/iso:2
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"A cation channel sperm-associated protein 2 isoform 2 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000000691 |
cation channel sperm-associated protein 2 isoform 3
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CATSPER2/iso:3
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"A cation channel sperm-associated protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96P56-3 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q96P56-3 |
cation channel sperm-associated protein 2 isoform 3 (human)
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hCATSPER2/iso:3
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"A cation channel sperm-associated protein 2 isoform 3 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000000692 |
cation channel sperm-associated protein 2 isoform m1
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CATSPER2/iso:m1
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"A cation channel sperm-associated protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:A2ARP9-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:A2ARP9-1 |
cation channel sperm-associated protein 2 isoform m1 (mouse)
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mCATSPER2/iso:m1
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"A cation channel sperm-associated protein 2 isoform m1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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gene
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PR:000000671 |
cation channel sperm-associated protein 3
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CATSPER3
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"A CatSper channel protein that is a translation product of the human CATSPER3 gene or a 1:1 ortholog thereof. In mammals, four CatSper ion channel subunit genes (CatSpers 1-4) are required for sperm cell hyperactivation and male fertility. The four proteins assemble (presumably as a tetramer) to form a sperm-specific, alkalinization-activated Ca(2+)-selective channel. CatSper channels seem to require auxiliary subunits, such as CatSperB (PR:000000672). In common with other channels, CatSper3 proteins have an architecture consisting of six transmembrane domains (S1-S6), arranged in a voltage sensor (S1-S4) and pore modules (S5-P-S6), and with both N and C termini on the intracellular side of the membrane." [PRO:CNA]
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organism-gene
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PR:Q80W99 |
cation channel sperm-associated protein 3 (mouse)
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mCATSPER3
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"A cation channel sperm-associated protein 3 that is encoded in the genome of mouse." [OMA:Q80W99, PRO:DNx]
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Yes |
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organism-sequence
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PR:Q80W99-1 |
cation channel sperm-associated protein 3 isoform 1 (mouse)
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mCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q80W99-2 |
cation channel sperm-associated protein 3 isoform 2 (mouse)
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mCATSPER3/iso:2
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"A cation channel sperm-associated protein 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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organism-gene
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PR:Q86XQ3 |
cation channel sperm-associated protein 3 (human)
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hCATSPER3
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"A cation channel sperm-associated protein 3 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q86XQ3]
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organism-sequence
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PR:Q86XQ3-1 |
cation channel sperm-associated protein 3 isoform 1 (human)
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hCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000000693 |
cation channel sperm-associated protein 3 isoform 1
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CATSPER3/iso:1
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"A cation channel sperm-associated protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80W99-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q80W99-1 |
cation channel sperm-associated protein 3 isoform 1 (mouse)
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mCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
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organism-sequence
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PR:Q86XQ3-1 |
cation channel sperm-associated protein 3 isoform 1 (human)
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hCATSPER3/iso:1
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"A cation channel sperm-associated protein 3 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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sequence
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PR:000000694 |
cation channel sperm-associated protein 3 isoform 2
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CATSPER3/iso:2
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"A cation channel sperm-associated protein 3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q80W99-2 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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organism-sequence
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PR:Q80W99-2 |
cation channel sperm-associated protein 3 isoform 2 (mouse)
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mCATSPER3/iso:2
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"A cation channel sperm-associated protein 3 isoform 2 that is encoded in the genome of mouse." [PRO:CNA]
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gene
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PR:000005063 |
cation channel sperm-associated protein 4
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CATSPER4
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"A CatSper channel protein that is a translation product of the human CATSPER4 gene or a 1:1 ortholog thereof." [PRO:DNx]
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organism-gene
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PR:Q7RTX7 |
cation channel sperm-associated protein 4 (human)
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hCATSPER4
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"A cation channel sperm-associated protein 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q7RTX7]
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organism-sequence
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PR:Q7RTX7-1 |
cation channel sperm-associated protein 4 isoform h1 (human)
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hCATSPER4/iso:h1
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"A cation channel sperm-associated protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7RTX7-1." [PRO:DNx, UniProtKB:Q7RTX7]
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organism-sequence
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PR:Q7RTX7-2 |
cation channel sperm-associated protein 4 isoform h2 (human)
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hCATSPER4/iso:h2
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"A cation channel sperm-associated protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q7RTX7-2." [PRO:DNx, UniProtKB:Q7RTX7]
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organism-gene
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PR:Q8BVN3 |
cation channel sperm-associated protein 4 (mouse)
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mCATSPER4
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"A cation channel sperm-associated protein 4 that is encoded in the genome of mouse." [OMA:Q8BVN3, PRO:DNx]
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