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Protein Ontology report - CatSper and two-pore channel protein
PR:000044647 - http://purl.obolibrary.org/obo/PR_000044647
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000044647   
  PRO nameCatSper and two-pore channel protein 
  Synonyms
PRO-Short-label: EXACT:fam:CS+2pore_chan
  Definition"A voltage-gated ion channel protein that is either a CatSper or two-pore channel protein." [PRO:XQ] 
  PRO Categoryfamily 
  ParentPR:000044628 voltage-gated ion channel protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family3                                                  Organism-Family 0                                        
         Gene6                                                  Organism-Gene 15                                        
         Sequence8                                                  Organism-Sequence 21                                        
         Modification1                                                  Organism-Modification 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARfam:70
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?
family



PR:000044647 CatSper and two-pore channel protein

fam:CS+2pore_chan


family



PR:000044645 CatSper channel protein

fam:CatSper_chan


gene



PR:000000669 cation channel sperm-associated protein 1

CATSPER1


organism-gene



PR:Q8NEC5 cation channel sperm-associated protein 1 (human)

hCATSPER1


organism-sequence



PR:Q8NEC5-1 cation channel sperm-associated protein 1 isoform 1 (human)

hCATSPER1/iso:1

Yes

organism-gene



PR:Q91ZR5 cation channel sperm-associated protein 1 (mouse)

mCATSPER1

Yes

organism-sequence



PR:Q91ZR5-1 cation channel sperm-associated protein 1 isoform 1 (mouse)

mCATSPER1/iso:1

Yes

sequence



PR:000000688 cation channel sperm-associated protein 1 isoform 1

CATSPER1/iso:1


organism-sequence



PR:Q91ZR5-1 cation channel sperm-associated protein 1 isoform 1 (mouse)

mCATSPER1/iso:1

Yes

modification



PR:000002581 cation channel sperm-associated protein 1 isoform 1 unmodified form

CATSPER1/iso:1/UnMod


gene



PR:000000670 cation channel sperm-associated protein 2

CATSPER2


organism-gene



PR:Q96P56 cation channel sperm-associated protein 2 (human)

hCATSPER2


organism-sequence



PR:Q96P56-1 cation channel sperm-associated protein 2 isoform 1 (human)

hCATSPER2/iso:1

Yes

organism-sequence



PR:Q96P56-2 cation channel sperm-associated protein 2 isoform 2 (human)

hCATSPER2/iso:2


organism-sequence



PR:Q96P56-3 cation channel sperm-associated protein 2 isoform 3 (human)

hCATSPER2/iso:3


organism-sequence



PR:Q96P56-4 cation channel sperm-associated protein 2 isoform h4 (human)

hCATSPER2/iso:h4


organism-gene



PR:A2ARP9 cation channel sperm-associated protein 2 (mouse)

mCATSPER2

Yes

organism-sequence



PR:A2ARP9-1 cation channel sperm-associated protein 2 isoform m1 (mouse)

mCATSPER2/iso:m1

Yes

organism-gene



PR:Q6AXP6 cation channel sperm-associated protein 2 (rat)

rCATSPER2


sequence



PR:000000689 cation channel sperm-associated protein 2 isoform 1

CATSPER2/iso:1


organism-sequence



PR:Q96P56-1 cation channel sperm-associated protein 2 isoform 1 (human)

hCATSPER2/iso:1

Yes

sequence



PR:000000690 cation channel sperm-associated protein 2 isoform 2

CATSPER2/iso:2


organism-sequence



PR:Q96P56-2 cation channel sperm-associated protein 2 isoform 2 (human)

hCATSPER2/iso:2


sequence



PR:000000691 cation channel sperm-associated protein 2 isoform 3

CATSPER2/iso:3


organism-sequence



PR:Q96P56-3 cation channel sperm-associated protein 2 isoform 3 (human)

hCATSPER2/iso:3


sequence



PR:000000692 cation channel sperm-associated protein 2 isoform m1

CATSPER2/iso:m1


organism-sequence



PR:A2ARP9-1 cation channel sperm-associated protein 2 isoform m1 (mouse)

mCATSPER2/iso:m1

Yes

gene



PR:000000671 cation channel sperm-associated protein 3

CATSPER3


organism-gene



PR:Q86XQ3 cation channel sperm-associated protein 3 (human)

hCATSPER3


organism-sequence



PR:Q86XQ3-1 cation channel sperm-associated protein 3 isoform 1 (human)

hCATSPER3/iso:1


organism-gene



PR:Q80W99 cation channel sperm-associated protein 3 (mouse)

mCATSPER3

Yes

organism-sequence



PR:Q80W99-1 cation channel sperm-associated protein 3 isoform 1 (mouse)

mCATSPER3/iso:1

Yes

organism-sequence



PR:Q80W99-2 cation channel sperm-associated protein 3 isoform 2 (mouse)

mCATSPER3/iso:2


sequence



PR:000000693 cation channel sperm-associated protein 3 isoform 1

CATSPER3/iso:1


organism-sequence



PR:Q86XQ3-1 cation channel sperm-associated protein 3 isoform 1 (human)

hCATSPER3/iso:1


organism-sequence



PR:Q80W99-1 cation channel sperm-associated protein 3 isoform 1 (mouse)

mCATSPER3/iso:1

Yes

sequence



PR:000000694 cation channel sperm-associated protein 3 isoform 2

CATSPER3/iso:2


organism-sequence



PR:Q80W99-2 cation channel sperm-associated protein 3 isoform 2 (mouse)

mCATSPER3/iso:2


gene



PR:000005063 cation channel sperm-associated protein 4

CATSPER4


organism-gene



PR:Q7RTX7 cation channel sperm-associated protein 4 (human)

hCATSPER4


organism-sequence



PR:Q7RTX7-1 cation channel sperm-associated protein 4 isoform h1 (human)

hCATSPER4/iso:h1


organism-sequence



PR:Q7RTX7-2 cation channel sperm-associated protein 4 isoform h2 (human)

hCATSPER4/iso:h2


organism-gene



PR:Q8BVN3 cation channel sperm-associated protein 4 (mouse)

mCATSPER4


family



PR:000044646 two-pore channel protein

fam:2pore_chan


gene



PR:000016570 two pore channel protein 1

TPCN1


organism-gene



PR:Q9EQJ0 two pore calcium channel protein 1 (mouse)

mTPCN1


organism-sequence



PR:Q9EQJ0-1 two pore calcium channel protein 1 isoform 1 (mouse)

mTPCN1/iso:1


organism-sequence



PR:Q9EQJ0-2 two pore calcium channel protein 1 isoform m2 (mouse)

mTPCN1/iso:m2


organism-gene



PR:Q9WTN5 two pore calcium channel protein 1 (rat)

rTPCN1


organism-sequence



PR:Q9WTN5-1 two pore channel protein 1 isoform 1 (rat)

rTPCN1/iso:1


organism-gene



PR:Q9ULQ1 two pore channel protein 1 (human)

hTPCN1


organism-modification



PR:000074015 two pore channel protein 1 deaminated 1 (human)

hTPCN1/Deam:1


organism-sequence



PR:Q9ULQ1-1 two pore channel protein 1 isoform h1 (human)

hTPCN1/iso:h1


organism-sequence



PR:Q9ULQ1-2 two pore channel protein 1 isoform h2 (human)

hTPCN1/iso:h2


organism-sequence



PR:Q9ULQ1-3 two pore channel protein 1 isoform h3 (human)

hTPCN1/iso:h3


sequence



PR:000043154 two pore channel protein 1 isoform 1

TPCN1/iso:1


organism-sequence



PR:Q9EQJ0-1 two pore calcium channel protein 1 isoform 1 (mouse)

mTPCN1/iso:1


organism-sequence



PR:Q9WTN5-1 two pore channel protein 1 isoform 1 (rat)

rTPCN1/iso:1


gene



PR:000001966 two pore channel protein 2

TPCN2


organism-gene



PR:Q8NHX9 two pore channel protein 2 (human)

hTPCN2


organism-modification



PR:000070661 two pore channel protein 2 cysteinylated 1 (human)

hTPCN2/Cyst:1


organism-gene



PR:Q8BWC0 two pore channel protein 2 (mouse)

mTPCN2


organism-sequence



PR:Q8BWC0-1 two pore channel protein 2 isoform m1 (mouse)

mTPCN2/iso:m1


organism-sequence



PR:Q8BWC0-2 two pore channel protein 2 isoform m2 (mouse)

mTPCN2/iso:m2


organism-sequence



PR:Q8BWC0-3 two pore channel protein 2 isoform m3 (mouse)

mTPCN2/iso:m3


organism-gene



PR:A0JMD4 two pore channel protein 2 (zebrafish)

z-TPCN2


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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:A2ARP9 mCATSPER2 acts_upstream_of_or_withinGO:0001539 cilium or flagellum-dependent cell motility PMID:14657366
GO:0030317 flagellated sperm motility PMID:14657366; PMID:17174296; PMID:17227845
PR:A2ARP9-1 mCATSPER2/iso:m1 located_inGO:0031514 motile cilium PMID:11675491; PMID:14657366
PR:Q80W99 mCATSPER3 acts_upstream_of_or_withinGO:0001539 cilium or flagellum-dependent cell motility PMID:17227845
GO:0030317 flagellated sperm motility PMID:17227845
located_inGO:0001669 acrosomal vesicle PMID:16107607
PR:Q80W99-1 mCATSPER3/iso:1 enablesGO:0005515 protein binding with PR:Q91ZR5-1 PMID:17227845
PR:Q8NEC5-1 hCATSPER1/iso:1 enablesGO:0005515 protein binding with PR:Q9P0X4 Ca(v)3.3 (human) PMID:16740636
PR:Q91ZR5 mCATSPER1 acts_upstream_of_or_withinGO:0006816 calcium ion transport PMID:11595941
GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization PMID:11595941
GO:0030317 flagellated sperm motility PMID:11595941
PR:Q91ZR5-1 mCATSPER1/iso:1 enablesGO:0005515 protein binding with PR:Q80W99-1 PMID:17227845
located_inGO:0005886 plasma membrane PMID:11595941
GO:0032991 protein-containing complex PMID:17478420
PR:Q96P56-1 hCATSPER2/iso:1 enablesGO:0005515 protein binding with PR:Q9P0X4 Ca(v)3.3 (human) PMID:16740636