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RACE-PRO
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Documentation
Protein Ontology report - smad2 isoform Long unphosphorylated 1 (human)
PR:000045371 -
http://purl.obolibrary.org/obo/PR_000045371
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:000045371
PRO name
smad2 isoform Long unphosphorylated 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hSMAD2/iso:Long/UnPhos:1
PRO-proteoform-std
:
EXACT:
UniProtKB:Q15796-1
, Ser-465/Ser-467,
PR:000026291
Definition
"A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human.
UniProtKB:Q15796-1
, Ser-465/Ser-467,
PR:000026291
." [PRO:CNA]
PRO Category
organism-modification
Parent
PR:Q15796
mothers against decapentaplegic homolog 2 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Term Hierarchy
Visualization
DAG:
OLS:
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hSMAD2/iso:Long/UnPhos:1
forms found in complexes
hSMAD2/iso:Long/UnPhos:1
Component
Complexes
PR:000045371
hSMAD2/iso:Long/UnPhos:1
PR:000025952
smad2-smad4-ski protein complex 2 (human)
PR:000025965
TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)
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Functional Annotation (GO-centric view)
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PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179
transforming growth factor beta receptor signaling pathway
PR:000045371
hSMAD2/iso:Long/UnPhos:1
PMID:8752209
Molecular Function GO Term
Protein Forms & Complexes
Evidence
GO:0005515
protein binding
PR:000045371
hSMAD2/iso:Long/UnPhos:1
PMID:8980228
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005737
cytoplasm
PR:000045371
hSMAD2/iso:Long/UnPhos:1
PMID:15280432
;
PMID:17074053
GO:0005769
early endosome
PR:000045371
hSMAD2/iso:Long/UnPhos:1
PMID:12356868