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Protein Ontology report - smad2 isoform Long unphosphorylated 1 (human)
PR:000045371 - http://purl.obolibrary.org/obo/PR_000045371
 
    Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:000045371   
  PRO namesmad2 isoform Long unphosphorylated 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hSMAD2/iso:Long/UnPhos:1
PRO-proteoform-std: EXACT:UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291
  Definition"A mothers against decapentaplegic homolog 2 isoform Long (human) that lacks phosphorylation on the two last Ser of the C-terminal SSxS motif in human. UniProtKB:Q15796-1, Ser-465/Ser-467, PR:000026291." [PRO:CNA] 
  PRO Categoryorganism-modification 
  ParentPR:Q15796 mothers against decapentaplegic homolog 2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS:
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hSMAD2/iso:Long/UnPhos:1 forms found in complexes   

hSMAD2/iso:Long/UnPhos:1 Component
Complexes
PR:000045371 hSMAD2/iso:Long/UnPhos:1 PR:000025952 smad2-smad4-ski protein complex 2 (human)
PR:000025965 TGF-beta 1:type II receptor:Phospho-type I receptor:SARA:SMAD2 complex (human)
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Functional Annotation (GO-centric view) Switch to PRO Centric View     

Biological Process GO Term

Protein Forms & Complexes

Evidence
GO:0007179 transforming growth factor beta receptor signaling pathwayPR:000045371 hSMAD2/iso:Long/UnPhos:1 PMID:8752209

Molecular Function GO Term

Protein Forms & Complexes

Evidence
GO:0005515 protein bindingPR:000045371 hSMAD2/iso:Long/UnPhos:1 PMID:8980228

Cellular Location GO Term

Protein Forms & Complexes

Evidence
GO:0005737 cytoplasmPR:000045371 hSMAD2/iso:Long/UnPhos:1 PMID:15280432; PMID:17074053
GO:0005769 early endosomePR:000045371 hSMAD2/iso:Long/UnPhos:1 PMID:12356868