|
PRO ID
 |
|
| PRO name | interferon regulatory factor 3 isoform 1 phosphorylated 2 (human) |
| Synonyms | | PRO-Short-label: | EXACT: | hIRF3/iso:1/Phos:2 | | PRO-proteoform-std: | EXACT: | UniProtKB:Q14653-1, Ser-339/Ser-396/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047 | | Other: | RELATED: | p-5S,T404-IRF3 (human) |
|
| Definition | "An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-339 and on Ser and Thr residues within the 5ST site (Ser-396, Ser-398, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-396/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047." [PRO:CNA, Reactome:R-HSA-936418] |
| Comment | Note: Reactome does not specify the precise isoform. However, it mentions that this proteoform is involved in dimerization. Based on the positions of the modified residues, and based on the position of the dimerization domain (203-385), only isoform 1 is eligible. [PRO:DAN, PMID:23824805]. |
| PRO Category | organism-modification |
| Parent | PR:000003259 interferon regulatory factor 3 isoform 1 phosphorylated form
PR:Q14653 interferon regulatory factor 3 (human)
|
| Taxon | NCBITaxon:9606 Homo sapiens |
Term Hierarchy
Visualization |
|
