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Protein Ontology report - platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human) PR:000049847 - http://purl.obolibrary.org/obo/PR_000049847        Annotations       Ontology Information Show OBO stanza / PAF / GPI   PRO ID PR:000049847      PRO name platelet-derived growth factor receptor beta, signal peptide removed phosphorylated 3 (human)    Synonyms PRO-Short-label: EXACT: hPDGFRB/SigPep-/Phos:3 PRO-proteoform-std: EXACT: UniProtKB:P09619, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 NARROW: UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046   Definition "A platelet-derived growth factor receptor beta (human) that has had the signal peptide removed and that has been phosphorylated on residues at positions equivalent to Tyr-857 and Ser-1104 of the amino acid sequence represented by UniProtKB:P09619-1. Example: UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046." [PMID:15271984, PMID:15994317, PRO:KER]    Comment Evidence=(ECO:0000006, based on PMID:15994317). Evidence=(ECO:0000006, based on PMID:15271984). Kinase=("PDGFRB"; PR:P09619; Tyr-857). Kinase=("GRK2"; PR:000003791; Ser-1104).    PRO Category organism-modification    Parent PR:000037070 phosphoprotein PR:000048725 platelet-derived growth factor receptor beta, signal peptide removed form (human)   Taxon NCBITaxon:9606 Homo sapiens   Term Hierarchy   Visualization DAG: OLS: Back to top Functional Annotation (PRO-centric view) Switch to GO Centric View    PRO Term GO Annotation Evidence PR:000049847 hPDGFRB/SigPep-/Phos:3 Example: UniProtKB:P09619-1, 33-1106, Tyr-857, MOD:00048|Ser-1104, MOD:00046 acts_upstream_of_or_within decreased GO:0051897 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984 enables decreased GO:0004713 protein tyrosine kinase activity relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984 decreased GO:0005515 protein binding relative to PR:000049846 hPDGFRB/SigPep-/Phos:2 PMID:15271984