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Protein Ontology report - E2F protein
PR:000050007 - http://purl.obolibrary.org/obo/PR_000050007
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000050007   
  PRO nameE2F protein 
  Synonyms
PRO-Short-label: EXACT:fam:E2F
  Definition"A protein that is a translation product of the human E2F1, E2F2, E2F3, E2F4, E2F5, E2F6, E2F7, or E2F8 genes, or 1:1 orthologs thereof." [PRO:DAN] 
  CommentRequested by=CRAFT. 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene8                                                  Organism-Gene 22                                        
         Sequence3                                                  Organism-Sequence 17                                        
         Modification4                                                  Organism-Modification 14                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000050007

E2F protein

fam:E2F


"A protein that is a translation product of the human E2F1, E2F2, E2F3, E2F4, E2F5, E2F6, E2F7, or E2F8 genes, or 1:1 orthologs thereof." [PRO:DAN]


gene



PR:000006852

transcription factor E2F1

E2F1


"An E2F protein that is a translation product of the human E2F1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O09139

transcription factor E2F1 (rat)

rE2F1


"A transcription factor E2F1 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q01094

transcription factor E2F1 (human)

hE2F1


"A transcription factor E2F1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q01094]


organism-sequence



PR:Q01094-1

transcription factor E2F1 isoform 1 (human)

hE2F1/iso:1


"A transcription factor E2F1 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028770

transcription factor E2F1 isoform 1 acetylated 1 (human)

hE2F1/iso:1/Ac:1


"A transcription factor E2F1 isoform 1 acetylated 1 in human. Acetylation increases DNA binding and transcriptional activation. UniProtKB:Q01094-1, Lys-117/Lys-120/Lys-125, MOD:00064." [PMID:10753885, PRO:PD]


organism-modification



PR:000047232

transcription factor E2F1 phosphorylated form (human)

hE2F1/PhosRes+


"A transcription factor E2F1 (human) that includes at least one phosphorylated residue. UniProtKB:Q01094, MOD:00696." [PRO:DNx, Reactome:R-HSA-187911]


organism-modification



PR:000045867

transcription factor E2F1 phosphorylated 1 (human)

hE2F1/Phos:1


"A transcription factor E2F1 (human) that has been phosphorylated at Ser-403. UniProtKB:Q01094, Ser-403, MOD:00046." [iPTMnet:Q01094, PMID:20447425]


organism-gene



PR:Q61501

transcription factor E2F1 (mouse)

mE2F1


"A transcription factor E2F1 that is encoded in the genome of mouse." [OMA:Q61501, PRO:DNx]


organism-gene



PR:Q90977

transcription factor E2F1 (chicken)

chick-E2F1


"A transcription factor E2F1 that is encoded in the genome of chicken." [PRO:DNx]


sequence



PR:000028767

transcription factor E2F1 isoform 1

E2F1/iso:1


"A transcription factor E2F1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q01094-1 or a 1:1 ortholog thereof." [PMID:10753885, PRO:PD]


organism-sequence



PR:Q01094-1

transcription factor E2F1 isoform 1 (human)

hE2F1/iso:1


"A transcription factor E2F1 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028770

transcription factor E2F1 isoform 1 acetylated 1 (human)

hE2F1/iso:1/Ac:1


"A transcription factor E2F1 isoform 1 acetylated 1 in human. Acetylation increases DNA binding and transcriptional activation. UniProtKB:Q01094-1, Lys-117/Lys-120/Lys-125, MOD:00064." [PMID:10753885, PRO:PD]


modification



PR:000028769

transcription factor E2F1 isoform 1 acetylated 1

E2F1/iso:1/Ac:1


"A transcription factor E2F1 isoform 1 that has been acetylated at three conserved Lys residues located at the N-terminal boundary of their DNA binding domains. Example: UniProtKB:Q01094-1, Lys-117/Lys-120/Lys-125, MOD:00064." [PMID:10753885, PRO:PD]


organism-modification



PR:000028770

transcription factor E2F1 isoform 1 acetylated 1 (human)

hE2F1/iso:1/Ac:1


"A transcription factor E2F1 isoform 1 acetylated 1 in human. Acetylation increases DNA binding and transcriptional activation. UniProtKB:Q01094-1, Lys-117/Lys-120/Lys-125, MOD:00064." [PMID:10753885, PRO:PD]


gene



PR:000006853

transcription factor E2F2

E2F2


"An E2F protein that is a translation product of the human E2F2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P56931

transcription factor E2F2 (mouse)

mE2F2


"A transcription factor E2F2 that is encoded in the genome of mouse." [OMA:P56931, PRO:DNx]


organism-gene



PR:Q14209

transcription factor E2F2 (human)

hE2F2


"A transcription factor E2F2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q14209]


organism-sequence



PR:Q14209-1

transcription factor E2F2 isoform 1 (human)

hE2F2/iso:1


"A transcription factor E2F2 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028774

transcription factor E2F2 isoform 1 acetylated 1 (human)

hE2F2/iso:1/Ac:1


"A transcription factor E2F2 isoform 1 acetylated 1 in human. Acetylation increases DNA binding and transcriptional activation. UniProtKB:Q14209-1, Lys-119/Lys-122/Lys-127, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


organism-modification



PR:000077892

transcription factor E2F2 deaminated 1 (human)

hE2F2/Deam:1


"A transcription factor E2F2 (human) that has been deaminated on the residue at the position equivalent to Gln-288 of the amino acid sequence represented by UniProtKB:Q14209. UniProtKB:Q14209, Gln-288, MOD:00685." [IEDB_epitope:1991869, PRO:DNx]


sequence



PR:000028771

transcription factor E2F2 isoform 1

E2F2/iso:1


"A transcription factor E2F2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14209-1 or a 1:1 ortholog thereof." [PMID:10753885, PRO:PD]


organism-sequence



PR:Q14209-1

transcription factor E2F2 isoform 1 (human)

hE2F2/iso:1


"A transcription factor E2F2 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028774

transcription factor E2F2 isoform 1 acetylated 1 (human)

hE2F2/iso:1/Ac:1


"A transcription factor E2F2 isoform 1 acetylated 1 in human. Acetylation increases DNA binding and transcriptional activation. UniProtKB:Q14209-1, Lys-119/Lys-122/Lys-127, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


modification



PR:000028773

transcription factor E2F2 isoform 1 acetylated 1

E2F2/iso:1/Ac:1


"A transcription factor E2F2 isoform 1 that has been acetylated at three conserved Lys residues located at the N-terminal boundary of their DNA binding domains. Example: UniProtKB:Q14209-1, Lys-119/Lys-122/Lys-127, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


organism-modification



PR:000028774

transcription factor E2F2 isoform 1 acetylated 1 (human)

hE2F2/iso:1/Ac:1


"A transcription factor E2F2 isoform 1 acetylated 1 in human. Acetylation increases DNA binding and transcriptional activation. UniProtKB:Q14209-1, Lys-119/Lys-122/Lys-127, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


gene



PR:000006854

transcription factor E2F3

E2F3


"An E2F protein that is a translation product of the human E2F3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O00716

transcription factor E2F3 (human)

hE2F3


"A transcription factor E2F3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00716]


organism-sequence



PR:O00716-1

transcription factor E2F3 isoform 1 (human)

hE2F3/iso:1


"A transcription factor E2F3 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028778

transcription factor E2F3 isoform 1 acetylated 1 (human)

hE2F3/iso:1/Ac:1


"A transcription factor E2F3 isoform 1 acetylated 1 in human. UniProtKB:O00716-1, Lys-168/Lys-171/Lys-176, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


organism-sequence



PR:O00716-2

transcription factor E2F3 isoform h2 (human)

hE2F3/iso:h2


"A transcription factor E2F3 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00716-2." [PRO:DNx, UniProtKB:O00716]


organism-modification



PR:000047233

transcription factor E2F3 phosphorylated form (human)

hE2F3/PhosRes+


"A transcription factor E2F3 (human) that includes at least one phosphorylated residue. UniProtKB:O00716, MOD:00696." [PRO:DNx, Reactome:R-HSA-187933]


organism-gene



PR:O35261

transcription factor E2F3 (mouse)

mE2F3


"A transcription factor E2F3 that is encoded in the genome of mouse." [OMA:O35261, PRO:DNx]


sequence



PR:000028775

transcription factor E2F3 isoform 1

E2F3/iso:1


"A transcription factor E2F3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00716-1 or a 1:1 ortholog thereof." [PMID:10753885, PRO:PD]


organism-sequence



PR:O00716-1

transcription factor E2F3 isoform 1 (human)

hE2F3/iso:1


"A transcription factor E2F3 isoform 1 that is encoded in the genome of human." [PRO:PD]


organism-modification



PR:000028778

transcription factor E2F3 isoform 1 acetylated 1 (human)

hE2F3/iso:1/Ac:1


"A transcription factor E2F3 isoform 1 acetylated 1 in human. UniProtKB:O00716-1, Lys-168/Lys-171/Lys-176, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


modification



PR:000028777

transcription factor E2F3 isoform 1 acetylated 1

E2F3/iso:1/Ac:1


"A transcription factor E2F3 isoform 1 that has been acetylated at three conserved Lys residues located at the N-terminal boundary of their DNA binding domains. Example: UniProtKB:O00716-1, Lys-168/Lys-171/Lys-176, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


organism-modification



PR:000028778

transcription factor E2F3 isoform 1 acetylated 1 (human)

hE2F3/iso:1/Ac:1


"A transcription factor E2F3 isoform 1 acetylated 1 in human. UniProtKB:O00716-1, Lys-168/Lys-171/Lys-176, MOD:00064." [PMID:10753885, PRO:CNA, PRO:PD]


gene



PR:000006855

transcription factor E2F4

E2F4


"An E2F protein that is a translation product of the human E2F4 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q16254

transcription factor E2F4 (human)

hE2F4


"A transcription factor E2F4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16254]


organism-modification



PR:000047234

transcription factor E2F4, initiator methionine removed form (human)

hE2F4/InitMet-


"A transcription factor E2F4 (human) that has had the initiator methionine removed. UniProtKB:Q16254, 2-413." [PRO:DNx, Reactome:R-HSA-68664]


organism-modification



PR:000067421

transcription factor E2F4 methylated 1 (human)

hE2F4/Me:1


"A transcription factor E2F4 (human) that has been methylated on the residue at the position equivalent to Cys-362 of the amino acid sequence represented by UniProtKB:Q16254. UniProtKB:Q16254, Cys-362, MOD:00660." [IEDB_epitope:1020435, PRO:DNx]


organism-modification



PR:000071637

transcription factor E2F4 cysteinylated 1 (human)

hE2F4/Cyst:1


"A transcription factor E2F4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-136 of the amino acid sequence represented by UniProtKB:Q16254. UniProtKB:Q16254, Cys-136, MOD:00765." [IEDB_epitope:1566562, PRO:DNx]


organism-modification



PR:000078427

transcription factor E2F4 cysteinylated 2 (human)

hE2F4/Cyst:2


"A transcription factor E2F4 (human) that has been cysteinylated on the residue at the position equivalent to Cys-362 of the amino acid sequence represented by UniProtKB:Q16254. UniProtKB:Q16254, Cys-362, MOD:00765." [IEDB_epitope:1020434, PRO:DNx]


organism-gene



PR:Q8R0K9

transcription factor E2F4 (mouse)

mE2F4


"A transcription factor E2F4 that is encoded in the genome of mouse." [OMA:Q8R0K9, PRO:DNx]


modification



PR:000019720

transcription factor E2F4, initiator methionine removed form

E2F4/InitMet-


"A transcription factor E2F4 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000047234

transcription factor E2F4, initiator methionine removed form (human)

hE2F4/InitMet-


"A transcription factor E2F4 (human) that has had the initiator methionine removed. UniProtKB:Q16254, 2-413." [PRO:DNx, Reactome:R-HSA-68664]


gene



PR:000006856

transcription factor E2F5

E2F5


"An E2F protein that is a translation product of the human E2F5 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:Q15329

transcription factor E2F5 (human)

hE2F5


"A transcription factor E2F5 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q15329]


organism-sequence



PR:Q15329-1

transcription factor E2F5 isoform h1 (human)

hE2F5/iso:h1


"A transcription factor E2F5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15329-1." [PRO:DNx, UniProtKB:Q15329]


organism-sequence



PR:Q15329-2

transcription factor E2F5 isoform h2 (human)

hE2F5/iso:h2


"A transcription factor E2F5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15329-2." [PRO:DNx, UniProtKB:Q15329]


organism-sequence



PR:Q15329-3

transcription factor E2F5 isoform h3 (human)

hE2F5/iso:h3


"A transcription factor E2F5 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q15329-3." [PRO:DNx, UniProtKB:Q15329]


organism-gene



PR:Q61502

transcription factor E2F5 (mouse)

mE2F5


"A transcription factor E2F5 that is encoded in the genome of mouse." [PRO:DNx]


gene



PR:000006857

transcription factor E2F6

E2F6


"An E2F protein that is a translation product of the human E2F6 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:O54917

transcription factor E2F6 (mouse)

mE2F6


"A transcription factor E2F6 that is encoded in the genome of mouse." [OMA:O54917, PRO:DNx]


organism-gene



PR:O75461

transcription factor E2F6 (human)

hE2F6


"A transcription factor E2F6 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O75461]


organism-sequence



PR:O75461-1

transcription factor E2F6 isoform h1 (human)

hE2F6/iso:h1


"A transcription factor E2F6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75461-1." [PRO:DNx, UniProtKB:O75461]


organism-sequence



PR:O75461-2

transcription factor E2F6 isoform h2 (human)

hE2F6/iso:h2


"A transcription factor E2F6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75461-2." [PRO:DNx, UniProtKB:O75461]


organism-sequence



PR:O75461-3

transcription factor E2F6 isoform h3 (human)

hE2F6/iso:h3


"A transcription factor E2F6 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O75461-3." [PRO:DNx, UniProtKB:O75461]


organism-modification



PR:000064519

transcription factor E2F6 phosphorylated 1 (human)

hE2F6/Phos:1


"A transcription factor E2F6 (human) that has been phosphorylated on the residue at the position equivalent to Ser-12 of the amino acid sequence represented by UniProtKB:O75461-1. Example: UniProtKB:O75461-1, Ser-12, MOD:00046." [PRO:DNx, Reactome:R-HSA-9007536]


organism-modification



PR:000077378

transcription factor E2F6 phosphorylated 2 (human)

hE2F6/Phos:2


"A transcription factor E2F6 (human) that has been phosphorylated on the residue at the position equivalent to Thr-184 of the amino acid sequence represented by UniProtKB:O75461-1. Example: UniProtKB:O75461-1, Thr-184, MOD:00047." [IEDB_epitope:2145997, PRO:DNx]


gene



PR:000006858

transcription factor E2F7

E2F7


"An E2F protein that is a translation product of the human E2F7 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:D4A4D7

transcription factor E2F7 (rat)

rE2F7


"A transcription factor E2F7 that is encoded in the genome of rat." [PRO:DNx]


organism-gene



PR:Q5RIX9

transcription factor E2F7 (zebrafish)

z-E2F7


"A transcription factor E2F7 that is encoded in the genome of zebrafish." [PANTHER:PTHR12081:SF25, PRO:DNx]


organism-gene



PR:Q6S7F2

transcription factor E2F7 (mouse)

mE2F7


"A transcription factor E2F7 that is encoded in the genome of mouse." [OMA:Q6S7F2, PRO:DNx]


organism-sequence



PR:Q6S7F2-1

transcription factor E2F7 isoform m1 (mouse)

mE2F7/iso:m1


"A transcription factor E2F7 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6S7F2-1." [PRO:DNx, UniProtKB:Q6S7F2]


organism-sequence



PR:Q6S7F2-2

transcription factor E2F7 isoform m2 (mouse)

mE2F7/iso:m2


"A transcription factor E2F7 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6S7F2-2." [PRO:DNx, UniProtKB:Q6S7F2]


organism-gene



PR:Q96AV8

transcription factor E2F7 (human)

hE2F7


"A transcription factor E2F7 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96AV8]


organism-sequence



PR:Q96AV8-1

transcription factor E2F7 isoform h1 (human)

hE2F7/iso:h1


"A transcription factor E2F7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96AV8-1." [PRO:DNx, UniProtKB:Q96AV8]


organism-sequence



PR:Q96AV8-2

transcription factor E2F7 isoform h2 (human)

hE2F7/iso:h2


"A transcription factor E2F7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96AV8-2." [PRO:DNx, UniProtKB:Q96AV8]


organism-sequence



PR:Q96AV8-3

transcription factor E2F7 isoform h3 (human)

hE2F7/iso:h3


"A transcription factor E2F7 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96AV8-3." [PRO:DNx, UniProtKB:Q96AV8]


gene



PR:000006859

transcription factor E2F8

E2F8


"An E2F protein that is a translation product of the human E2F8 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:A0AVK6

transcription factor E2F8 (human)

hE2F8


"A transcription factor E2F8 that is encoded in the genome of human." [PRO:DNx, UniProtKB:A0AVK6]


organism-modification



PR:000083847

transcription factor E2F8 methylated 1 (human)

hE2F8/Me:1


"A transcription factor E2F8 (human) that has been methylated on the residue at the position equivalent to Cys-96 of the amino acid sequence represented by UniProtKB:A0AVK6. UniProtKB:A0AVK6, Cys-96, MOD:00660." [IEDB_epitope:1023208, PRO:DNx]


organism-gene



PR:F1LMN3

transcription factor E2F8 (rat)

rE2F8


"A transcription factor E2F8 that is encoded in the genome of rat." [OMA:F1LMN3, PRO:DNx]


organism-sequence



PR:F1LMN3-1

transcription factor E2F8 isoform r1 (rat)

rE2F8/iso:r1


"A transcription factor E2F8 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F1LMN3-1." [PRO:DNx, UniProtKB:F1LMN3]


organism-sequence



PR:F1LMN3-2

transcription factor E2F8 isoform r2 (rat)

rE2F8/iso:r2


"A transcription factor E2F8 (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:F1LMN3-2." [PRO:DNx, UniProtKB:F1LMN3]


organism-gene



PR:F1QZ88

transcription factor E2F8 (zebrafish)

z-E2F8


"A transcription factor E2F8 that is encoded in the genome of zebrafish." [OMA:F1QZ88, PRO:DNx]


organism-gene



PR:Q58FA4

transcription factor E2F8 (mouse)

mE2F8


"A transcription factor E2F8 that is encoded in the genome of mouse." [OMA:Q58FA4, PRO:DNx]