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Protein Ontology report - F-actin-capping protein subunit alpha
PR:000050027 - http://purl.obolibrary.org/obo/PR_000050027
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000050027   
  PRO nameF-actin-capping protein subunit alpha 
  Synonyms
PRO-Short-label: EXACT:fam:CAPZA
Other: EXACT:CapZ alpha
RELATED:Cappa
  Definition"A protein that is a translation product of the human CAPZA1, CAPZA2, or CAPZA3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN] 
  PRO Categoryfamily 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene3                                                  Organism-Gene 17                                        
         Sequence3                                                  Organism-Sequence 9                                        
         Modification2                                                  Organism-Modification 13                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
family



PR:000050027

F-actin-capping protein subunit alpha

fam:CAPZA


"A protein that is a translation product of the human CAPZA1, CAPZA2, or CAPZA3 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]


gene



PR:000005029

F-actin-capping protein subunit alpha-1

CAPZA1


"An F-actin-capping protein subunit alpha that is a translation product of the human CAPZA1 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:B2GUZ5

F-actin-capping protein subunit alpha-1 (rat)

rCAPZA1


"An F-actin-capping protein subunit alpha-1 that is encoded in the genome of rat." [OMA:B2GUZ5, PRO:DNx]


organism-gene



PR:P13127

F-actin-capping protein subunit alpha-1 (chicken)

chick-CAPZA1


"An F-actin-capping protein subunit alpha-1 that is encoded in the genome of chicken." [OMA:P13127, PRO:DNx]


organism-sequence



PR:P13127-1

F-actin-capping protein subunit alpha-1 isoform 1 (chicken)

chick-CAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-gene



PR:P47753

F-actin-capping protein subunit alpha-1 (mouse)

mCAPZA1


"An F-actin-capping protein subunit alpha-1 that is encoded in the genome of mouse." [OMA:P47753, PMID:9331217, PRO:KRC]


Yes
organism-sequence



PR:P47753-1

F-actin-capping protein subunit alpha-1 isoform 1 (mouse)

mCAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-modification



PR:000079195

F-actin-capping protein subunit alpha-1 cysteinylated 1 (mouse)

mCAPZA1/Cyst:1


"An F-actin-capping protein subunit alpha-1 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-141 of the amino acid sequence represented by UniProtKB:P47753. UniProtKB:P47753, Cys-141, MOD:00765." [IEDB_epitope:2096382, PRO:DNx]


organism-gene



PR:P52907

F-actin-capping protein subunit alpha-1 (human)

hCAPZA1


"An F-actin-capping protein subunit alpha-1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P52907]


organism-sequence



PR:P52907-1

F-actin-capping protein subunit alpha-1 isoform 1 (human)

hCAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-modification



PR:000046563

F-actin-capping protein subunit alpha-1, initiator methionine removed form (human)

hCAPZA1/InitMet-


"An F-actin-capping protein subunit alpha-1 (human) that has had the initiator methionine removed. UniProtKB:P52907, 2-286." [PRO:DNx, Reactome:R-HSA-879363]


organism-modification



PR:000066138

F-actin-capping protein subunit alpha-1 deaminated 1 (human)

hCAPZA1/Deam:1


"An F-actin-capping protein subunit alpha-1 (human) that has been deaminated on the residue at the position equivalent to Asn-92 of the amino acid sequence represented by UniProtKB:P52907. UniProtKB:P52907, Asn-92, MOD:00684." [IEDB_epitope:555565, PRO:DNx]


organism-modification



PR:000075984

F-actin-capping protein subunit alpha-1 methylated 1 (human)

hCAPZA1/Me:1


"An F-actin-capping protein subunit alpha-1 (human) that has been methylated on the residue at the position equivalent to Cys-141 of the amino acid sequence represented by UniProtKB:P52907. UniProtKB:P52907, Cys-141, MOD:00660." [IEDB_epitope:1062522, PRO:DNx]


organism-modification



PR:000079831

F-actin-capping protein subunit alpha-1 cysteinylated 1 (human)

hCAPZA1/Cyst:1


"An F-actin-capping protein subunit alpha-1 (human) that has been cysteinylated on the residue at the position equivalent to Cys-141 of the amino acid sequence represented by UniProtKB:P52907. UniProtKB:P52907, Cys-141, MOD:00765." [IEDB_epitope:1062521, PRO:DNx]


organism-modification



PR:000082391

F-actin-capping protein subunit alpha-1 deaminated 2 (human)

hCAPZA1/Deam:2


"An F-actin-capping protein subunit alpha-1 (human) that has been deaminated on the residue at the position equivalent to Gln-162 of the amino acid sequence represented by UniProtKB:P52907. UniProtKB:P52907, Gln-162, MOD:00685." [IEDB_epitope:1813499, PRO:DNx]


organism-modification



PR:000084751

F-actin-capping protein subunit alpha-1 deaminated 3 (human)

hCAPZA1/Deam:3


"An F-actin-capping protein subunit alpha-1 (human) that has been deaminated on the residue at the position equivalent to Gln-151 of the amino acid sequence represented by UniProtKB:P52907. UniProtKB:P52907, Gln-151, MOD:00685." [IEDB_epitope:1360243, PRO:DNx]


sequence



PR:000039719

F-actin-capping protein subunit alpha-1 isoform 1

CAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P52907-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P13127-1

F-actin-capping protein subunit alpha-1 isoform 1 (chicken)

chick-CAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 isoform 1 that is encoded in the genome of chicken." [PRO:DNx]


organism-sequence



PR:P47753-1

F-actin-capping protein subunit alpha-1 isoform 1 (mouse)

mCAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:P52907-1

F-actin-capping protein subunit alpha-1 isoform 1 (human)

hCAPZA1/iso:1


"An F-actin-capping protein subunit alpha-1 isoform 1 that is encoded in the genome of human." [PRO:DNx]


modification



PR:000019235

F-actin-capping protein subunit alpha-1, initiator methionine removed form

CAPZA1/InitMet-


"An F-actin-capping protein subunit alpha-1 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000046563

F-actin-capping protein subunit alpha-1, initiator methionine removed form (human)

hCAPZA1/InitMet-


"An F-actin-capping protein subunit alpha-1 (human) that has had the initiator methionine removed. UniProtKB:P52907, 2-286." [PRO:DNx, Reactome:R-HSA-879363]


gene



PR:000005030

F-actin-capping protein subunit alpha-2

CAPZA2


"An F-actin-capping protein subunit alpha that is a translation product of the human CAPZA2 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P28497

F-actin-capping protein subunit alpha-2 (chicken)

chick-CAPZA2


"An F-actin-capping protein subunit alpha-2 that is encoded in the genome of chicken." [OMA:P28497, PRO:DNx]


organism-gene



PR:P47754

F-actin-capping protein subunit alpha-2 (mouse)

mCAPZA2


"An F-actin-capping protein subunit alpha-2 that is encoded in the genome of mouse." [OMA:P47754, PMID:15850461, PMID:9331217, PRO:KRC]


Yes
organism-sequence



PR:P47754-1

F-actin-capping protein subunit alpha-2 isoform 1 (mouse)

mCAPZA2/iso:1


"An F-actin-capping protein subunit alpha-2 isoform 1 that is encoded in the genome of mouse." [PRO:KRC]


organism-modification



PR:000073027

F-actin-capping protein subunit alpha-2 cysteinylated 1 (mouse)

mCAPZA2/Cyst:1


"An F-actin-capping protein subunit alpha-2 (mouse) that has been cysteinylated on the residue at the position equivalent to Cys-95 of the amino acid sequence represented by UniProtKB:P47754. UniProtKB:P47754, Cys-95, MOD:00765." [IEDB_epitope:2096521, PRO:DNx]


organism-gene



PR:P47755

F-actin-capping protein subunit alpha-2 (human)

hCAPZA2


"An F-actin-capping protein subunit alpha-2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P47755]


organism-sequence



PR:P47755-1

F-actin-capping protein subunit alpha-2 isoform h1 (human)

hCAPZA2/iso:h1


"An F-actin-capping protein subunit alpha-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47755-1." [PRO:DNx, UniProtKB:P47755]


organism-sequence



PR:P47755-2

F-actin-capping protein subunit alpha-2 isoform h2 (human)

hCAPZA2/iso:h2


"An F-actin-capping protein subunit alpha-2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47755-2." [PRO:DNx, UniProtKB:P47755]


organism-modification



PR:000046564

F-actin-capping protein subunit alpha-2, initiator methionine removed form (human)

hCAPZA2/InitMet-


"An F-actin-capping protein subunit alpha-2 (human) that has had the initiator methionine removed. UniProtKB:P47755, 2-286." [PRO:DNx, Reactome:R-HSA-879448]


organism-modification



PR:000065359

F-actin-capping protein subunit alpha-2 methylated 1 (human)

hCAPZA2/Me:1


"An F-actin-capping protein subunit alpha-2 (human) that has been methylated on the residue at the position equivalent to Cys-111 of the amino acid sequence represented by UniProtKB:P47755-1. Example: UniProtKB:P47755-1, Cys-111, MOD:00660." [IEDB_epitope:1002755, PRO:DNx]


organism-modification



PR:000076838

F-actin-capping protein subunit alpha-2 phosphorylated 1 (human)

hCAPZA2/Phos:1


"An F-actin-capping protein subunit alpha-2 (human) that has been phosphorylated on the residue at the position equivalent to Thr-77 of the amino acid sequence represented by UniProtKB:P47755-1. Example: UniProtKB:P47755-1, Thr-77, MOD:00047." [IEDB_epitope:1357710, PRO:DNx]


organism-modification



PR:000080078

F-actin-capping protein subunit alpha-2 methylated 2 (human)

hCAPZA2/Me:2


"An F-actin-capping protein subunit alpha-2 (human) that has been methylated on the residue at the position equivalent to Cys-157 of the amino acid sequence represented by UniProtKB:P47755-1. Example: UniProtKB:P47755-1, Cys-157, MOD:00660." [IEDB_epitope:1016387, PRO:DNx]


organism-modification



PR:000084814

F-actin-capping protein subunit alpha-2 cysteinylated 1 (human)

hCAPZA2/Cyst:1


"An F-actin-capping protein subunit alpha-2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-141 of the amino acid sequence represented by UniProtKB:P47755-1. Example: UniProtKB:P47755-1, Cys-141, MOD:00765." [IEDB_epitope:1338182, PRO:DNx]


organism-gene



PR:Q3T1K5

F-actin-capping protein subunit alpha-2 (rat)

rCAPZA2


"An F-actin-capping protein subunit alpha-2 that is encoded in the genome of rat." [OMA:Q3T1K5, PRO:DNx]


sequence



PR:000035841

F-actin-capping protein subunit alpha-2 isoform 1

CAPZA2/iso:1


"An F-actin-capping protein subunit alpha-2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P47754-1 or a 1:1 ortholog thereof." [PRO:KRC]


organism-sequence



PR:P47754-1

F-actin-capping protein subunit alpha-2 isoform 1 (mouse)

mCAPZA2/iso:1


"An F-actin-capping protein subunit alpha-2 isoform 1 that is encoded in the genome of mouse." [PRO:KRC]


modification



PR:000019236

F-actin-capping protein subunit alpha-2, initiator methionine removed form

CAPZA2/InitMet-


"An F-actin-capping protein subunit alpha-2 that has had the initiator methionine removed." [PRO:DNx]


organism-modification



PR:000046564

F-actin-capping protein subunit alpha-2, initiator methionine removed form (human)

hCAPZA2/InitMet-


"An F-actin-capping protein subunit alpha-2 (human) that has had the initiator methionine removed. UniProtKB:P47755, 2-286." [PRO:DNx, Reactome:R-HSA-879448]


gene



PR:000005031

F-actin-capping protein subunit alpha-3

CAPZA3


"An F-actin-capping protein subunit alpha that is a translation product of the human CAPZA3 gene or a 1:1 ortholog thereof." [PRO:DNx]


organism-gene



PR:P70190

F-actin-capping protein subunit alpha-3 (mouse)

mCAPZA3


"An F-actin-capping protein subunit alpha-3 that is encoded in the genome of mouse." [OMA:P70190, PMID:19341723, PRO:KRC]

Yes

organism-sequence



PR:P70190-1

F-actin-capping protein subunit alpha-3 isoform 1 (mouse)

mCAPZA3/iso:1


"An F-actin-capping protein subunit alpha-3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-gene



PR:Q96KX2

F-actin-capping protein subunit alpha-3 (human)

hCAPZA3


"An F-actin-capping protein subunit alpha-3 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96KX2]


organism-sequence



PR:Q96KX2-1

F-actin-capping protein subunit alpha-3 isoform 1 (human)

hCAPZA3/iso:1


"An F-actin-capping protein subunit alpha-3 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-gene



PR:Q9WUV6

F-actin-capping protein subunit alpha-3 (rat)

rCAPZA3


"An F-actin-capping protein subunit alpha-3 that is encoded in the genome of rat." [OMA:Q9WUV6, PRO:DNx]


sequence



PR:000042591

F-actin-capping protein subunit alpha-3 isoform 1

CAPZA3/iso:1


"An F-actin-capping protein subunit alpha-3 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q96KX2-1 or a 1:1 ortholog thereof." [PRO:DNx]


organism-sequence



PR:P70190-1

F-actin-capping protein subunit alpha-3 isoform 1 (mouse)

mCAPZA3/iso:1


"An F-actin-capping protein subunit alpha-3 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]


organism-sequence



PR:Q96KX2-1

F-actin-capping protein subunit alpha-3 isoform 1 (human)

hCAPZA3/iso:1


"An F-actin-capping protein subunit alpha-3 isoform 1 that is encoded in the genome of human." [PRO:DNx]


organism-gene



PR:O82631

F-actin-capping protein subunit alpha (Arabidopsis thaliana)

At-CAPZA1


"An F-actin-capping protein subunit alpha that is a translation product of the At3g05520 gene in Arabidopsis thaliana." [PRO:DAN]


organism-sequence



PR:O82631-1

F-actin-capping protein subunit alpha isoform 1 (Arabidopsis thaliana)

At-CAPZA1/iso:1


"An F-actin-capping protein subunit alpha (Arabidopsis thaliana) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O82631-1." [PRO:DNx, UniProtKB:O82631]


organism-gene



PR:P13022

F-actin-capping protein subunit alpha (Dictyostelium discoideum)

Dicty-CAPZA1


"An F-actin-capping protein subunit alpha that is a translation product of the acpB gene in Dictyostelium discoideum." [PRO:DAN]


organism-gene



PR:P28495

F-actin-capping protein subunit alpha (yeast)

yCAPZA1


"An F-actin-capping protein subunit alpha that is a translation product of the CAP1 gene in yeast." [PRO:DAN]


organism-gene



PR:P34685

F-actin-capping protein subunit alpha (worm)

CAPZA1 (worm)


"An F-actin-capping protein subunit alpha that is a translation product of the cap-1 gene in worm." [PRO:DAN]


organism-gene



PR:Q10434

F-actin-capping protein subunit alpha (Schizosaccharomyces pombe 972h-)

Spom972h-CAPZA2


"An F-actin-capping protein subunit alpha that is encoded in the genome of Schizosaccharomyces pombe 972h-." [PRO:DNx]


organism-gene



PR:Q9W2N0

F-actin-capping protein subunit alpha (fruit fly)

fly-CAPZA1


"An F-actin-capping protein subunit alpha that is a translation product of the cpa gene in fruit fly." [PRO:DAN]


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fam:CAPZA forms found in complexes   

fam:CAPZA Component
Complexes
PR:P47753 mCAPZA1 PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)
PR:P47754 mCAPZA2 PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P70190 mCAPZA3 acts_upstream_of_or_withinGO:0007286 spermatid development MGI_ref:3848085; PMID:19341723
located_incolocalizes_with GO:0001669 acrosomal vesicle MGI_ref:3848085; PMID:19341723