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PRO ID
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| PRO name | secretory polymeric IgA1 immunoglobulin complex (human) |
| Synonyms | | PRO-Short-label: | EXACT: | h(IgA1/secretory)polymeric | | Other: | EXACT: | secretory IgA1 antibody (human) | sIgA1 antibody (human) | | | |
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| Definition | "A polymeric IgA1 immunoglobulin complex (human) that is complexed with one chain of secretory component (SC). Polymeric IgA1 is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component." [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD] |
| Comment | Requested by=HIPC. Requested by=CL. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA. |
| PRO Category | organism-complex |
| Parent | PR:000050165 polymeric IgA1 immunoglobulin complex (human)
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| Taxon | NCBITaxon:9606 Homo sapiens |
Term Hierarchy
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