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Protein Ontology report - IgG heavy chain protein
PR:000050252 - http://purl.obolibrary.org/obo/PR_000050252
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000050252   
  PRO nameIgG heavy chain protein 
  Synonyms
PRO-Short-label: EXACT:IgHG
Other: EXACT:immunoglobulin G heavy chain | immunoglobulin gamma heavy chain | immunoglobulin heavy chain gamma
  Definition"An immunoglobulin heavy chain protein in which the constant region is encoded by some IgG gene segment." [PRO:DAN] 
  CommentRequested by=IEDB. Note: In human, IgG constant gene segments are IgG1, IgG2, IgG3, and IgG4. 
  PRO Categoryfamily 
  ParentPR:000050174 immunoglobulin heavy chain protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Family1                                                  Organism-Family 0                                        
         Gene0                                                  Organism-Gene 0                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
family


PR:000050252
IgG heavy chain protein
IgHG
"An immunoglobulin heavy chain protein in which the constant region is encoded by some IgG gene segment." [PRO:DAN]

seqgroup


PR:000050253
IgG1 heavy chain protein
IgHG1
"An IgG heavy chain protein in which the constant region is encoded by the IgG1 gene segment." [PRO:DAN]

organism-seqgroup


PR:000050291
IgG1 heavy chain protein (human)
hIgHG1
"An IgG1 heavy chain protein that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050297
IgG1 heavy chain protein, secretory isoform (human)
hIgHG1/iso:secretory
"An IgG1 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050301
IgG1 heavy chain protein, membrane-bound isoform (human)
hIgHG1/iso:membrane-bound
"An IgG1 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
seqgroup


PR:000050254
IgG2 heavy chain protein
IgHG2
"An IgG heavy chain protein in which the constant region is encoded by the IgG2 gene segment." [PRO:DAN]

organism-seqgroup


PR:000050292
IgG2 heavy chain protein (human)
hIgHG2
"An IgG2 heavy chain protein that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050298
IgG2 heavy chain protein, secretory isoform (human)
hIgHG2/iso:secretory
"An IgG2 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050302
IgG2 heavy chain protein, membrane-bound isoform (human)
hIgHG2/iso:membrane-bound
"An IgG2 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
seqgroup


PR:000050255
IgG3 heavy chain protein
IgHG3
"An IgG heavy chain protein in which the constant region is encoded by the IgG3 gene segment." [PRO:DAN]

organism-seqgroup


PR:000050293
IgG3 heavy chain protein (human)
hIgHG3
"An IgG3 heavy chain protein that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050299
IgG3 heavy chain protein, secretory isoform (human)
hIgHG3/iso:secretory
"An IgG3 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050303
IgG3 heavy chain protein, membrane-bound isoform (human)
hIgHG3/iso:membrane-bound
"An IgG3 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
seqgroup


PR:000050256
IgG4 heavy chain protein
IgHG4
"An IgG heavy chain protein in which the constant region is encoded by the IgG4 gene segment." [PRO:DAN]

organism-seqgroup


PR:000050294
IgG4 heavy chain protein (human)
hIgHG4
"An IgG4 heavy chain protein that is encoded in the genome of human." [GOC:add, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050300
IgG4 heavy chain protein, secretory isoform (human)
hIgHG4/iso:secretory
"An IgG4 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
organism-seqgroup


PR:000050304
IgG4 heavy chain protein, membrane-bound isoform (human)
hIgHG4/iso:membrane-bound
"An IgG4 heavy chain protein (human) that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

Yes
seqgroup


PR:000050259
IgG2a heavy chain protein
IgHG2a
"An IgG heavy chain protein in which the constant region is encoded by the IgG2a gene segment." [PRO:DAN]

seqgroup


PR:000050260
IgG2b heavy chain protein
IgHG2b
"An IgG heavy chain protein in which the constant region is encoded by the IgG2b gene segment." [PRO:DAN]

seqgroup


PR:000050261
IgG2c heavy chain protein
IgHG2c
"An IgG heavy chain protein in which the constant region is encoded by the IgG2c gene segment." [PRO:DAN]

seqgroup


PR:000050295
IgG heavy chain protein, secretory isoform
IgHG/iso:secretory
"An IgG heavy chain protein that is a translation product of some mRNA polyadenylated at a site 5' to the membrane exons, thus preventing their incorporation the final spliced mRNA." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

seqgroup


PR:000050296
IgG heavy chain protein, membrane-bound isoform
IgHG/iso:membrane-bound
"An IgG heavy chain protein that is a translation product of some mRNA polyadenylated at a site 3' to the membrane exons." [GOC:add, PMID:17496345, PMID:9185563, PRO:ADD, PRO:DAN]

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IgHG forms found in complexes   

IgHG Component
 Complexes
PR:000050291 hIgHG1 PR:000050305 IgG1 immunoglobulin complex (human)
PR:000050292 hIgHG2 PR:000050306 IgG2 immunoglobulin complex (human)
PR:000050293 hIgHG3 PR:000050307 IgG3 immunoglobulin complex (human)
PR:000050294 hIgHG4 PR:000050308 IgG4 immunoglobulin complex (human)
PR:000050297 hIgHG1/iso:secretory PR:000050309 IgG1 immunoglobulin complex, circulating (human)
PR:000050298 hIgHG2/iso:secretory PR:000050310 IgG2 immunoglobulin complex, circulating (human)
PR:000050299 hIgHG3/iso:secretory PR:000050311 IgG3 immunoglobulin complex, circulating (human)
PR:000050300 hIgHG4/iso:secretory PR:000050312 IgG4 immunoglobulin complex, circulating (human)
PR:000050301 hIgHG1/iso:membrane-bound PR:000050313 IgG1 B cell receptor complex (human)
PR:000050302 hIgHG2/iso:membrane-bound PR:000050314 IgG2 B cell receptor complex (human)
PR:000050303 hIgHG3/iso:membrane-bound PR:000050315 IgG3 B cell receptor complex (human)
PR:000050304 hIgHG4/iso:membrane-bound PR:000050316 IgG4 B cell receptor complex (human)