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Protein Ontology report - severe acute respiratory syndrome coronavirus 2 protein
PR:000050262 - http://purl.obolibrary.org/obo/PR_000050262
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000050262   
  PRO namesevere acute respiratory syndrome coronavirus 2 protein 
  Synonyms
PRO-Short-label: EXACT:SARS2 protein
Other: EXACT:2019-nCoV protein | SARS-CoV-2 protein
  Definition"A protein that is encoded in the genome of Severe acute respiratory syndrome coronavirus 2." [PRO:DAN] 
  ParentPR:000036197 viral protein
  TaxonNCBITaxon:2697049 Severe acute respiratory syndrome coronavirus 2
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?




PR:000050262

severe acute respiratory syndrome coronavirus 2 protein

SARS2 protein


"A protein that is encoded in the genome of Severe acute respiratory syndrome coronavirus 2." [PRO:DAN]


organism-gene



PR:000050263

rep gene translation product (SARS-CoV-2)

ORF1ab (SARS2)


"A protein that is a translation product of the ORF1ab gene in SARS-CoV-2." [PRO:DAN]


organism-sequence



PR:P0DTC1-1

replicase polyprotein 1a (SARS-CoV-2)

rep/iso:ORF1a (SARS2)


"A rep gene translation product (SARS-CoV-2) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0DTC1-1." [GenPept:YP_009725295, PRO:DAN, UniProtKB:P0DTC1]


organism-modification



PR:000050282

ORF1a proteolytic cleavage product (SARS-CoV-2)

ORF1a/ClvPrd (SARS2)


"A replicase polyprotein 1a (SARS-CoV-2) that has been processed by proteolytic cleavage." [PRO:DAN]


organism-modification



PR:000050280

non-structural protein 11 (SARS-CoV-2)

rep/Clv:nsp11 (SARS2)


"An ORF1a proteolytic cleavage product (SARS-CoV-2) that is the C-terminal portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1a (SARS-CoV-2) between residues 4392-4393. UniProtKB:P0DTC1, 4393-4405." [GenPept:YP_009725312, PRO:DAN, UniProtKB:P0DTC1]


organism-sequence



PR:P0DTD1-1

replicase polyprotein 1ab (SARS-CoV-2)

rep/iso:ORF1ab (SARS2)


"A rep gene translation product (SARS-CoV-2) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0DTD1-1. Requires ribosomal frameshifting." [GenPept:YP_009724389, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050283

ORF1ab proteolytic cleavage product (SARS-CoV-2)

ORF1ab/ClvPrd (SARS2)


"A replicase polyprotein 1ab (SARS-CoV-2) that has been processed by proteolytic cleavage." [PRO:DAN]


organism-modification



PR:000050284

RNA-directed RNA polymerase nsp12 (SARS-CoV-2)

ORF1ab/Clv:nsp12 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 4392-4393 and 5324-5325. UniProtKB:P0DTD1, 4393-5324." [GenPept:YP_009725307, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050285

helicase nsp13 (SARS-CoV-2)

ORF1ab/Clv:nsp13 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 5324-5325 and 5925-5926. UniProtKB:P0DTD1, 4393-5324." [GenPept:YP_009725308, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050286

proofreading exoribonuclease nsp14 (SARS-CoV-2)

ORF1ab/Clv:nsp14 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 5925-5926 and 6452-6453. UniProtKB:P0DTD1, 4393-5324." [GenPept:YP_009725309, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050287

uridylate-specific endoribonuclease nsp15 (SARS-CoV-2)

ORF1ab/Clv:nsp15 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 6452-6453 and 6798-6799. UniProtKB:P0DTD1, 6453-6798." [GenPept:YP_009725310, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050288

2'-O-methyltransferase nsp16 (SARS-CoV-2)

ORF1ab/Clv:nsp16 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the C-terminal portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 6798-6799. UniProtKB:P0DTD1, 6453-6798." [GenPept:YP_009725311, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050281

rep gene proteolytic cleavage product (SARS-CoV-2)

rep/ClvPrd (SARS2)


"A rep gene translation product (SARS-CoV-2) that has been processed by proteolytic cleavage." [PRO:DAN]


organism-modification



PR:000050270

host translation inhibitor nsp1 (SARS-CoV-2)

rep/Clv:nsp1 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the N-terminal portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181." [GenPept:YP_009725297, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050271

non-structural protein 2 (SARS-CoV-2)

rep/Clv:nsp2 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181 and 818-819." [GenPept:YP_009725298, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050272

papain-like proteinase nsp3 (SARS-CoV-2)

rep/Clv:nsp3 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the autocatalytic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 818-819 and 2763-2764." [GenPept:YP_009725299, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050273

non-structural protein 4 (SARS-CoV-2)

rep/Clv:nsp4 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the combined actions of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 2763-2764, and 3CL-PRO (nsp5) when it cleaves the precursor between residues 3263-3264." [GenPept:YP_009725300, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050274

3C-like proteinase nsp5 (SARS-CoV-2)

rep/Clv:nsp5 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the autocatalytic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3263-3264 and 3569-3570." [GenPept:YP_009725301, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050275

non-structural protein 6 (SARS-CoV-2)

rep/Clv:nsp6 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3569-3570 and 3859-3860." [GenPept:YP_009725302, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050276

non-structural protein 7 (SARS-CoV-2)

rep/Clv:nsp7 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3859-3860 and 3942-3943." [GenPept:YP_009725303, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050277

non-structural protein 8 (SARS-CoV-2)

rep/Clv:nsp8 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 3942-3943 and 4140-4141." [GenPept:YP_009725304, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050278

non-structural protein 9 (SARS-CoV-2)

rep/Clv:nsp9 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 4140-4141 and 4253-4254." [GenPept:YP_009725305, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050279

non-structural protein 10 (SARS-CoV-2)

rep/Clv:nsp10 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 4253-4254 and 4392-4393." [GenPept:YP_009725306, PRO:DAN, UniProtKB:P0DTC1, UniProtKB:P0DTD1]


organism-modification



PR:000050282

ORF1a proteolytic cleavage product (SARS-CoV-2)

ORF1a/ClvPrd (SARS2)


"A replicase polyprotein 1a (SARS-CoV-2) that has been processed by proteolytic cleavage." [PRO:DAN]


organism-modification



PR:000050280

non-structural protein 11 (SARS-CoV-2)

rep/Clv:nsp11 (SARS2)


"An ORF1a proteolytic cleavage product (SARS-CoV-2) that is the C-terminal portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1a (SARS-CoV-2) between residues 4392-4393. UniProtKB:P0DTC1, 4393-4405." [GenPept:YP_009725312, PRO:DAN, UniProtKB:P0DTC1]


organism-modification



PR:000050283

ORF1ab proteolytic cleavage product (SARS-CoV-2)

ORF1ab/ClvPrd (SARS2)


"A replicase polyprotein 1ab (SARS-CoV-2) that has been processed by proteolytic cleavage." [PRO:DAN]


organism-modification



PR:000050284

RNA-directed RNA polymerase nsp12 (SARS-CoV-2)

ORF1ab/Clv:nsp12 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 4392-4393 and 5324-5325. UniProtKB:P0DTD1, 4393-5324." [GenPept:YP_009725307, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050285

helicase nsp13 (SARS-CoV-2)

ORF1ab/Clv:nsp13 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 5324-5325 and 5925-5926. UniProtKB:P0DTD1, 4393-5324." [GenPept:YP_009725308, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050286

proofreading exoribonuclease nsp14 (SARS-CoV-2)

ORF1ab/Clv:nsp14 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 5925-5926 and 6452-6453. UniProtKB:P0DTD1, 4393-5324." [GenPept:YP_009725309, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050287

uridylate-specific endoribonuclease nsp15 (SARS-CoV-2)

ORF1ab/Clv:nsp15 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 6452-6453 and 6798-6799. UniProtKB:P0DTD1, 6453-6798." [GenPept:YP_009725310, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050288

2'-O-methyltransferase nsp16 (SARS-CoV-2)

ORF1ab/Clv:nsp16 (SARS2)


"An ORF1ab proteolytic cleavage product (SARS-CoV-2) that is the C-terminal portion produced by the enzymatic action of 3CL-PRO proteinase (nsp5) when it cleaves the precursor replicase polyprotein 1ab (SARS-CoV-2) between residues 6798-6799. UniProtKB:P0DTD1, 6453-6798." [GenPept:YP_009725311, PRO:DAN, UniProtKB:P0DTD1]


organism-modification



PR:000050289

NSP2-3 intermediate (SARS-CoV-2)

rep/Clv:nsp2-3 (SARS2)


"A rep gene proteolytic cleavage product (SARS-CoV-2) that is the central portion produced by the enzymatic action of PL-PRO proteinase (nsp3) when it cleaves the precursor rep gene translation product (SARS-CoV-2) between residues 180-181 and 2763-2764." [PRO:DAN]


organism-gene



PR:A0A663DJA2

putative ORF10 protein (SARS-CoV-2)

ORF10 (SARS2)


"A protein that is a translation product of the ORF10 gene in SARS-CoV-2." [GenPept:YP_009725255, PRO:DAN, UniProtKB:A0A663DJA2]


organism-gene



PR:P0DTC2

spike glycoprotein (SARS-CoV-2)

S (SARS2)


"A protein that is a translation product of the S gene in SARS-CoV-2." [GenPept:YP_009724390, PRO:DAN, UniProtKB:P0DTC2]


organism-modification



PR:000050266

spike glycoprotein, signal peptide removed form (SARS-CoV-2)

S/SigPep- (SARS2)


"A spike glycoprotein (SARS-CoV-2) that has had the signal peptide removed. UniProtKB:P0DTC2, 14-1273." [PRO:DAN, UniProtKB:P0DTC2]


organism-modification



PR:000050267

spike protein S1 (SARS-CoV-2)

S1 (SARS2)


"A spike glycoprotein, signal peptide removed form (SARS-CoV-2) that has been processed by proteolytic cleavage to yield the N-terminal portion. UniProtKB:P0DTC2, 13-685." [PRO:DAN, UniProtKB:P0DTC2]


organism-modification



PR:000050268

spike protein S2 (SARS-CoV-2)

S2 (SARS2)


"A spike glycoprotein, signal peptide removed form (SARS-CoV-2) that has been processed by proteolytic cleavage to yield the C-terminal portion. UniProtKB:P0DTC2, 686-1273." [PRO:DAN, UniProtKB:P0DTC2]


organism-modification



PR:000050269

spike protein S2' (SARS-CoV-2)

S2' (SARS2)


"A spike protein S2 (SARS-CoV-2) that has been further processed by proteolytic cleavage to yield the C-terminal portion. UniProtKB:P0DTC2, 816-1273." [PRO:DAN, UniProtKB:P0DTC2]


organism-gene



PR:P0DTC3

ORF3a protein (SARS-CoV-2)

ORF3a (SARS2)


"A protein that is a translation product of the ORF3a gene in SARS-CoV-2." [GenPept:YP_009724391, PRO:DAN, UniProtKB:P0DTC3]


organism-gene



PR:P0DTC4

envelope small membrane protein (SARS-CoV-2)

E (SARS2)


"A protein that is a translation product of the E gene in SARS-CoV-2." [GenPept:YP_009724392, PRO:DAN, UniProtKB:P0DTC4]


organism-gene



PR:P0DTC5

membrane protein (SARS-CoV-2)

M (SARS2)


"A protein that is a translation product of the M gene in SARS-CoV-2." [GenPept:YP_009724393, PRO:DAN, UniProtKB:P0DTC5]


organism-gene



PR:P0DTC6

ORF6 protein (SARS-CoV-2)

ORF6 (SARS2)


"A protein that is a translation product of the ORF6 gene in SARS-CoV-2." [GenPept:YP_009724394, PRO:DAN, UniProtKB:P0DTC6]


organism-gene



PR:P0DTC7

ORF7a protein (SARS-CoV-2)

ORF7a (SARS2)


"A protein that is a translation product of the ORF7a gene in SARS-CoV-2." [GenPept:YP_009724395, PRO:DAN, UniProtKB:P0DTC7]


organism-modification



PR:000050265

ORF7a protein, signal peptide removed form (SARS-CoV-2)

7a/SigPep- (SARS2)


"An ORF7a protein (SARS-CoV-2) that has had the signal peptide removed. UniProtKB:P0DTC7, 16-121." [PRO:DAN, UniProtKB:P0DTC7]


organism-gene



PR:P0DTC8

ORF8 protein (SARS-CoV-2)

ORF8 (SARS2)


"A protein that is a translation product of the ORF8 gene in SARS-CoV-2." [GenPept:YP_009724396, PRO:DAN, UniProtKB:P0DTC8]


organism-modification



PR:000050264

ORF8 protein, signal peptide removed form (SARS-CoV-2)

ORF8/SigPep- (SARS2)


"An ORF8 protein (SARS-CoV-2) that has had the signal peptide removed. UniProtKB:P0DTC8, 16-121." [PRO:DAN, UniProtKB:P0DTC8]


organism-gene



PR:P0DTC9

nucleoprotein (SARS-CoV-2)

N (SARS2)


"A protein that is a translation product of the N gene in SARS-CoV-2." [GenPept:YP_009724397, PRO:DAN, UniProtKB:P0DTC9]


organism-gene



PR:P0DTD2

ORF9b protein (SARS-CoV-2)

ORF9b (SARS2)


"A protein that is a translation product of the ORF9b gene in SARS-CoV-2." [PRO:DAN, UniProtKB:P0DTD2]


organism-gene



PR:P0DTD3

putative ORF9c protein (SARS-CoV-2)

ORF9c (SARS2)


"A protein that is a translation product of the ORF9c gene in SARS-CoV-2." [PRO:DAN, UniProtKB:P0DTD3]


organism-gene



PR:P0DTD8

ORF7b protein (SARS-CoV-2)

ORF7b (SARS2)


"A protein that is a translation product of the ORF7b gene in SARS-CoV-2." [GenPept:YP_009725318, PRO:DAN, UniProtKB:P0DTD8]


organism-gene



PR:P0DTF1

putative ORF3b protein (SARS-CoV-2)

ORF3b (SARS2)


"A protein that is a translation product of the ORF3b gene in SARS-CoV-2." [PRO:DAN, UniProtKB:P0DTF1]


organism-gene



PR:P0DTG0

putative ORF3d protein (SARS-CoV-2)

ORF3d (SARS2)


"A protein that is a translation product of the ORF3d gene in SARS-CoV-2." [PRO:DAN, UniProtKB:P0DTG0]


organism-gene



PR:P0DTG1

ORF3c protein (SARS-CoV-2)

ORF3c (SARS2)


"A protein that is a translation product of the ORF3c gene in SARS-CoV-2." [PRO:DAN, UniProtKB:P0DTG1]