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Protein Ontology report - IgG2 immunoglobulin complex (human)
PR:000050306 -
http://purl.obolibrary.org/obo/PR_000050306
Protein Forms
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:000050306
PRO name
IgG2 immunoglobulin complex (human)
Synonyms
PRO-Short-label
:
EXACT:
hIgG2
Other
:
EXACT:
IgG2 (human)
NARROW:
IgG2 antibody (human)
Definition
"An IgG immunoglobulin complex in human that is composed of two identical immunoglobulin heavy chains of an IgG2 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. An IgG2 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add,
PMID:25368619
, PRO:ADD]
Comment
Requested by=HIPC. Requested by=CL. Note: An IgG2 immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
PRO Category
organism-complex
Parent
G0071735
IgG immunoglobulin complex
PR:000050032
immunoglobulin complex (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
0
Organism-Complex
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
organism-complex
PR:000050306
IgG2 immunoglobulin complex (human)
hIgG2
"An IgG immunoglobulin complex in human that is composed of two identical immunoglobulin heavy chains of an IgG2 isotype and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds. An IgG2 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, PMID:25368619, PRO:ADD]
organism-complex
PR:000050310
IgG2 immunoglobulin complex, circulating (human)
hIgG2/circulating
"An IgG2 immunoglobulin complex (human) that is composed of two identical immunoglobulin heavy chains of an IgG2 isotype of the secretory isoform and two identical immunoglobulin light chains (kappa or lambda), held together by disulfide bonds and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph." [GOC:add, PMID:25368619, PRO:ADD]
organism-complex
PR:000050314
IgG2 B cell receptor complex (human)
hIgG2/B-cell-receptor
"An IgG2 immunoglobulin complex (human) that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the membrane-bound isoform of the IgG2 isotype, two identical immunoglobulin light chains (kappa or lambda), and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins." [GOC:add, ISBN:0781765196, PMID:17496345, PRO:ADD]
