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Protein Ontology report - L-lactate dehydrogenase, cytoplasmic
PR:000050332 - http://purl.obolibrary.org/obo/PR_000050332
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000050332   
  PRO nameL-lactate dehydrogenase, cytoplasmic 
  Synonyms
PRO-Short-label: EXACT:LDH-cyto
  Definition"A protein that is a translation product of the Schizosaccharomyces pombe SPAC186.08c gene, a 1:1 ortholog thereof, or pro-orthologs thereof." [PRO:DAN] 
  CommentPro-orthology refers to, in this case, after-speciation gene duplication in the non-yeast species (aka 1:many orthology). 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene6                                                  Organism-Gene 20                                        
         Sequence2                                                  Organism-Sequence 9                                        
         Modification3                                                  Organism-Modification 11                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000050332 L-lactate dehydrogenase, cytoplasmic
LDH-cyto

Yes
gene


PR:000009739 L-lactate dehydrogenase A chain
LDHA

Yes
organism-gene


PR:P00338 L-lactate dehydrogenase A chain (human)
hLDHA

organism-sequence


PR:P00338-1 L-lactate dehydrogenase A chain isoform h1 (human)
hLDHA/iso:h1

organism-sequence


PR:P00338-2 L-lactate dehydrogenase A chain isoform h2 (human)
hLDHA/iso:h2

organism-sequence


PR:P00338-3 L-lactate dehydrogenase A chain isoform h3 (human)
hLDHA/iso:h3

organism-sequence


PR:P00338-4 L-lactate dehydrogenase A chain isoform h4 (human)
hLDHA/iso:h4

organism-sequence


PR:P00338-5 L-lactate dehydrogenase A chain isoform h5 (human)
hLDHA/iso:h5

organism-modification


PR:000048179 L-lactate dehydrogenase A chain, initiator methionine removed form (human)
hLDHA/InitMet-

Yes
organism-modification


PR:000068524 L-lactate dehydrogenase A chain methylated 1 (human)
hLDHA/Me:1

organism-modification


PR:000072366 L-lactate dehydrogenase A chain glutathionylated 1 (human)
hLDHA/SGlt:1

organism-modification


PR:000074825 L-lactate dehydrogenase A chain deaminated 1 (human)
hLDHA/Deam:1

organism-modification


PR:000082679 L-lactate dehydrogenase A chain hydroxylated 1 (human)
hLDHA/Hy:1

organism-modification


PR:000082816 L-lactate dehydrogenase A chain methylated 2 (human)
hLDHA/Me:2

organism-modification


PR:000083019 L-lactate dehydrogenase A chain cysteinylated 1 (human)
hLDHA/Cyst:1

organism-gene


PR:P00340 L-lactate dehydrogenase A chain (chicken)
chick-LDHA

organism-gene


PR:P04642 L-lactate dehydrogenase A chain (rat)
rLDHA

organism-gene


PR:P06151 L-lactate dehydrogenase A chain (mouse)
mLDHA

organism-gene


PR:Q27888 L-lactate dehydrogenase (worm)
LDHA (worm)

organism-gene


PR:Q95028 L-lactate dehydrogenase (fruit fly)
fly-LDHA

organism-gene


PR:Q9P7P7 probable L-lactate dehydrogenase (Schizosaccharomyces pombe 972h-)
Spom972h-LDHA

organism-gene


PR:Q9PVK5 L-lactate dehydrogenase A chain (zebrafish)
z-ldha

modification


PR:000020451 L-lactate dehydrogenase A chain, initiator methionine removed form
LDHA/InitMet-

organism-modification


PR:000048179 L-lactate dehydrogenase A chain, initiator methionine removed form (human)
hLDHA/InitMet-

Yes
gene


PR:000009740 L-lactate dehydrogenase A-like 6A
LDHAL6A

organism-gene


PR:Q6ZMR3 L-lactate dehydrogenase A-like 6A (human)
hLDHAL6A

organism-modification


PR:000048180 L-lactate dehydrogenase A-like 6A, initiator methionine removed form (human)
hLDHAL6A/InitMet-

gene


PR:000009741 L-lactate dehydrogenase A-like 6B
LDHAL6B

organism-gene


PR:Q9BYZ2 L-lactate dehydrogenase A-like 6B (human)
hLDHAL6B

gene


PR:000009742 L-lactate dehydrogenase B chain
LDHB

Yes
organism-gene


PR:P00336 L-lactate dehydrogenase B chain (pig)
pig-LDHB

organism-gene


PR:P00337 L-lactate dehydrogenase B chain (chicken)
chick-LDHB

organism-gene


PR:P07195 L-lactate dehydrogenase B chain (human)
hLDHB

organism-sequence


PR:P07195-1 L-lactate dehydrogenase B chain isoform 1 (human)
hLDHB/iso:1

organism-modification


PR:000048181 L-lactate dehydrogenase B chain, initiator methionine removed form (human)
hLDHB/InitMet-

Yes
organism-modification


PR:000069763 L-lactate dehydrogenase B chain deaminated 1 (human)
hLDHB/Deam:1

organism-modification


PR:000078749 L-lactate dehydrogenase B chain cysteinylated 1 (human)
hLDHB/Cyst:1

organism-gene


PR:P16125 L-lactate dehydrogenase B chain (mouse)
mLDHB

organism-sequence


PR:P16125-1 L-lactate dehydrogenase B chain isoform 1 (mouse)
mLDHB/iso:1

organism-gene


PR:P42123 L-lactate dehydrogenase B chain (rat)
rLDHB

organism-sequence


PR:P42123-1 L-lactate dehydrogenase B chain isoform 1 (rat)
rLDHB/iso:1

organism-gene


PR:Q6DGK2 L-lactate dehydrogenase B-B chain (zebrafish)
z-ldhbb

organism-gene


PR:Q9PVK4 L-lactate dehydrogenase B-A chain (zebrafish)
z-ldhba

sequence


PR:000038703 L-lactate dehydrogenase B chain isoform 1
LDHB/iso:1

organism-sequence


PR:P07195-1 L-lactate dehydrogenase B chain isoform 1 (human)
hLDHB/iso:1

organism-sequence


PR:P16125-1 L-lactate dehydrogenase B chain isoform 1 (mouse)
mLDHB/iso:1

organism-sequence


PR:P42123-1 L-lactate dehydrogenase B chain isoform 1 (rat)
rLDHB/iso:1

modification


PR:000020452 L-lactate dehydrogenase B chain, initiator methionine removed form
LDHB/InitMet-

organism-modification


PR:000048181 L-lactate dehydrogenase B chain, initiator methionine removed form (human)
hLDHB/InitMet-

Yes
gene


PR:000009743 L-lactate dehydrogenase C chain
LDHC

organism-gene


PR:P00342 L-lactate dehydrogenase C chain (mouse)
mLDHC

organism-sequence


PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse)
mLDHC/iso:1
Yes
organism-gene


PR:P07864 L-lactate dehydrogenase C chain (human)
hLDHC

organism-gene


PR:P19629 L-lactate dehydrogenase C chain (rat)
rLDHC

sequence


PR:000028631 L-lactate dehydrogenase C chain isoform 1
LDHC/iso:1

organism-sequence


PR:P00342-1 L-lactate dehydrogenase C chain isoform 1 (mouse)
mLDHC/iso:1
Yes
modification


PR:000020453 L-lactate dehydrogenase C chain, initiator methionine removed form
LDHC/InitMet-

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LDH-cyto forms found in complexes   

LDH-cyto Component
 Complexes
PR:000009739 LDHA PR:000050327 lactate dehydrogenase complex 2
PR:000050328 lactate dehydrogenase complex 3
PR:000050329 lactate dehydrogenase complex 4
PR:000050330 lactate dehydrogenase complex 5
PR:000009742 LDHB PR:000050326 lactate dehydrogenase complex 1
PR:000050327 lactate dehydrogenase complex 2
PR:000050328 lactate dehydrogenase complex 3
PR:000050329 lactate dehydrogenase complex 4
PR:000048179 hLDHA/InitMet- PR:000050363 lactate dehydrogenase complex 2 (human)
PR:000050364 lactate dehydrogenase complex 3 (human)
PR:000050365 lactate dehydrogenase complex 4 (human)
PR:000050366 lactate dehydrogenase complex 5 (human)
PR:000048181 hLDHB/InitMet- PR:000050362 lactate dehydrogenase complex 1 (human)
PR:000050363 lactate dehydrogenase complex 2 (human)
PR:000050364 lactate dehydrogenase complex 3 (human)
PR:000050365 lactate dehydrogenase complex 4 (human)
PR:000050332 LDH-cyto PR:000050331 lactate dehydrogenase complex
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P00342-1 mLDHC/iso:1 acts_upstream_of_or_withinGO:0006089 lactate metabolic process PMID:18367675
GO:0006090 pyruvate metabolic process PMID:18367675
enablesGO:0004459 L-lactate dehydrogenase (NAD+) activity PMID:18367675
located_inGO:0005737 cytoplasm PMID:18367675
GO:0031514 motile cilium PMID:18367675