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Protein Ontology report - epidermal growth factor receptor sequence variant T790M/L858R, signal peptide removed phosphorylated 1 (human)
PR:000062650 - http://purl.obolibrary.org/obo/PR_000062650
 
     
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:000062650   
  PRO nameepidermal growth factor receptor sequence variant T790M/L858R, signal peptide removed phosphorylated 1 (human) 
  Synonyms
PRO-Short-label: EXACT:hEGFR/var:(T790M/L858R)/SigPep-/Phos:1
PRO-proteoform-std: EXACT:UniProtKB:P00533, 25-1210, Thr-790, CHEBI:16044|Leu-858, CHEBI:29952|Tyr-1016/Tyr-1069/Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048
NARROW:UniProtKB:P00533-1, 25-1210, Thr-790, CHEBI:16044|Leu-858, CHEBI:29952|Tyr-1016/Tyr-1069/Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048
Reactome-displayName: RELATED:p-6Y-EGFR L858R;T790M
  Definition"An epidermal growth factor receptor (human) that has a Met residue at the position equivalent to Thr-790 and an Arg residue at the position equivalent to Leu-858 of the amino acid sequence represented by UniProtKB:P00533-1, that has had the signal peptide removed, and that has been phosphorylated on the residues at the positions equivalent to Tyr-1016, Tyr-1069, Tyr-1092, Tyr-1110, Tyr-1172, and Tyr-1197. Example: UniProtKB:P00533-1, 25-1210, Thr-790, CHEBI:16044|Leu-858, CHEBI:29952|Tyr-1016/Tyr-1069/Tyr-1092/Tyr-1110/Tyr-1172/Tyr-1197, MOD:00048." [PRO:DNx, Reactome:R-HSA-1182984
  PRO Categoryorganism-modification 
  ParentPR:000028422 epidermal growth factor receptor, signal peptide removed form (human)
PR:000037070 phosphoprotein
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
  Visualization
DAG: OLS: